Faculty

Bridget Carragher 
Associate Professor of Cell Biology
Department of Cell Biology
TSRI - 2001

Joint Appointments 
Center for Integrative Molecular Biosciences

Education 
Ph.D., University of Chicago, 1987

Awards & Activities 
Member, American Society of Cell Biology
Editorial Board, Journal of Structural Biology

Research Focus 
Automated Molecular Microscopy

The focus of our group is the development of automated imaging techniques for solving the three-dimensional structure of macromolecular complexes using cryoTEM. Our current goal is to develop new methods to improve the throughput of the entire process, from specimen preparation to the generation of the final three-dimensional map.

Selected References 
Mouche, Fabrice, Yuanxin Zhu, James Pulokas, Clinton S. Potter, and Bridget Carragher "Automated three-dimensional reconstruction of keyhole limpet hemocyanin type 1". JSB, 144, 301-312. 2003

Zhu, Yuanxin, Bridget Carragher, Robert M. Glaeser, Denis Fellmann, Chandrajit Bajaj, Marshall Bern, Fabrice Mouche, Felix de Haas, Richard J. Hall, Steven C. Ludtke, Pawel A. Penczek, Alan M. Roseman, Fred J. Sigworth, Niels Volkmann, and Clinton S. Potter, "Automatic Particle Selection: Results of A "Bakeoff"", JSB, 145, 3-14. 2003

Ward, Andrew, Michael F. Moody, Brian Sheehan, Ronald A. Milligan and Bridget Carragher, "Windex: a toolset for indexing helices", JSB, 144, 172-183. 2003

Potter, Clinton S., James Pulokas, Paul Smith, Christian Suloway and Bridget Carragher. "Robotic Grid Loading System for a Transmission Electron Microscope", JSB, 146, 431-440. 2004