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Faculty
Nicholas Schork
Professor
Department of Molecular and Experimental Medicine
TSRI - 2007
Joint Appointments
Director of Research, Scripps Health, Scripps Genomic Medicine
Education
1982–1985 University of Michigan, B.A. (Philosophy)
1986–1992 University of Michigan, M.A. (Philosophy)
1988–1991 University of Michigan, M.A. (Applied Statistics)
1991–1994 University of Michigan, Ph.D. (Epidemiology)
Previous Appointments
University of California at San Diego
Faculty
2004-2007: Professor of Biostatistics, Department of Family & Preventive Medicine
2001-2007: Professor of Psychiatry (with tenure), Department of Psychiatry
2001: Visiting Professor, Department of Psychiatry
Academic
2006-Prsnt : Executive Committee Member, the San Diego Supercomputer Center
2004-Prsnt: Co-Director, Center for Human Genetics and Genomics
2004-Prsnt: Professor, Biomedical Sciences Graduate Program
2001-Prsnt: Founding Professor, Bioinformatics Graduate Program
2006-2007: Deputy Director of Research, Stein Institute for Research on Aging
2005-2007: Director, Scientific Advisory Board, Stein Institute for Research on Aging
2006-2007: Director, Biomedical Informatics, UCSD Moores Cancer Center
2006-2007: Co-director, Cancer Genetics Program, UCSD Moores Cancer Center
San Diego State University
2004 – 2006: Adjunct Clinical Professor in the Graduate School of Public Health
Case Western Reserve University
1997–2001: Associate Professor, Department of Epidemiology & Biostatistics
1995–1997: Assistant Professor, Department of Epidemiology & Biostatistics
1995–1998: Assistant Professor (secondary faculty), Department of Genetics
1994–1995: Assistant Professor, Department of Genetics
Harvard University School of Public Health
1998–2001: Associate Professor (adjunct), Department of Biostatistics
1995–1997: Assistant Professor (adjunct), Department of Biostatistics
Cleveland Clinic Foundation
1996–2001: Assistant Scientist (adjunct staff), Department of Biostatistics and Epidemiology
The Genset Corporation
1999–2000: Vice President, Statistical Genomics, La Jolla, California
Awards & Activities
Singapore
2007-Present: Member, NUS-GIS Center for Molecular Epidemiology, International Advisory Panel
2007-Present: Member, The Singapore Consortium of Cohort Studies, International Advisory Panel
National
2003-2007: Member, National Academy of Sciences Food and Nutrition Board
2002-2006: Member, National Academy of Sciences Twin Analysis Subcommittee
Editorial Boards
2007-Present: Associate Editor, Public Library of Science (PLoS): Genetics
2000-Present: Associate Editor, American Journal of Pharmacogenetics
2002-Present: Associate Editor, (Statistical Genetics), American Journal of Psychiatry
2000-2003: Scientific Advisor, Encyclopedia of Human Genetics
2002-Present: Scientific Advisor, Encyclopedia of Diagnostic Genomics and Proteomics
2000-2003: Associate Editor, Physiological Genomics
1999-2001: Associate Editor, American Journal of Human Genetics
1998-2002: Section Editor, Current Hypertension Reports
1995-1999: Associate Editor, Gene-COMBIS
Research Focus
Genetic Analysis of Complex Human Phenotypes
Dr. Schork and his laboratory focus on the development and implementation of analysis methods for understanding the genetic determinants of complex human traits and diseases such as cancer, neuropsychiatric disease, and cardiovascular disease. These methods focus on both the design of studies making use of contemporary high-throughput, high-dimensional genomic technologies such as DNA sequencing technologies, multilocus genotyping technologies, and DNA microarrays, as well the interpretation of the results obtained from studies making use of these technologies. Dr. Schork and his laboratory also consider the integration of studies making use of different technologies. In addition, Dr. Schork has a long history of collaborative research in which he has contributed data analysis methodology and data analysis expertise. For example, Dr. Schork is the Director of the Bioinformatics and Biostatistics Core of the NIA-sponsored Longevity Consortium (http://www.longevityconsortium.org/), the Director of statistical genetics for the NIMH-sponsored Consortium on the Genetics of Schizophrenia (http://www.npistat.com/cogs/), the Director of Data Analysis for the GAIN funded Bipolar Consortium and a statistical geneticist for the NHLBI-sponsored Family Blood Pressure Program (http://www.sph.uth.tmc.edu/hgc/fbpp/).
Selected References
Nievergelt CM, Libiger O, Schork NJ. Generalized analysis of molecular variance. PLoS Genet. 2007 Apr 6;3(4):e51. Epub 2007 Feb 22.
Torkamani A, Schork NJ. Accurate prediction of deleterious protein kinase polymorphisms. Bioinformatics. 2007 Nov 1;23(21):2918-25. Epub 2007 Sep 12.
Wessel J, Schork NJ. Generalized genomic distance-based regression methodology for multilocus association analysis. Am J Hum Genet. 2006 Nov;79(5):792-806. Epub 2006 Sep 21.
Zapala MA, Schork NJ. Multivariate regression analysis of distance matrices for testing associations between gene expression patterns and related variables. Proc Natl Acad Sci U S A. 2006 Dec 19;103(51):19430-5. Epub 2006 Dec 4.
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