Paulson Laboratory

Shrawan Ratan Chavan, Ph.D.
 
The Scripps Research Institute
10550 North Torrey Pines Road, MB-214
La Jolla, CA 92037
858-784-9691 (phone)
schavan@scripps.edu

EDUCATIONS:

2018 - Ph.D. Chemistry, Savitribai Phule Pune University (Formerly University of Pune), Pune (India)

2010 - M.S. Organic Chemistry, University of Pune (India)

2008 - B.S. Chemistry, University of Pune (India)



PROFESSIONAL EXPERIENCES:

November 2022 to Present: Postdoctoral Associate @ The Scripps Research Institute, La Jolla, CA, USA (Advisor: Prof. James C. Paulson)

October 2019 to October 2022: Research Scientist @ Jubilant Biosys Limited, Noida, India

January 2019 to May 2019: Postdoctoral Fellow @ Shanghai Jiao-Tong University, Shanghai, China (Advisor: Prof. Wenjie Peng)

April 2012 to January 2018: PhD Candidate @ Garware research centre, Department of Chemistry, Savitribai Phule Pune University (Formerly University of Pune), Pune India (Advisor: Prof. Dilip D. Dhavale)

Sept 2010 to June 2011: Trainee Executive @ Megafine Pharmaceuticals, Nasik, India



AWARDS:

2014–2017: CSIR, New Delhi, India (Senior Research Fellow)

2012–2014: CSIR-Research Grants, India (Junior Research Fellow)

2010: University of Pune, India (Second Prize for Inter collegiate 'CHEMQUIZE' competition in chemistry)



PUBLICATIONS:

Dandekar PD, Kotmale AS, Chavan SR, Kadlag PP, Sawant SV, Dhavale DD, RaviKumar A. (2021) Insights into the Inhibition Mechanism of Human Pancreatic α-Amylase, a Type 2 Diabetes Target, by Dehydrodieugenol B Isolated from Ocimum tenuiflorum. ACS Omega 6: 1780-6

Gavale KS, Chavan SR, Kumbhar N, Kawade S, Doshi P, Khan A, Dhavale DD. (2017) α-Geminal disubstituted pyrrolidine iminosugars and their C-4-fluoro analogues: Synthesis, glycosidase inhibition and molecular docking studies. Bioorganic & Medicinal Chemistry 25: 5148-59

Chavan SR, Gavale KS, Khan A, Joshi R, Kumbhar N, Chakravarty D, Dhavale DD. (2017) Iminosugars Spiro-Linked with Morpholine-Fused 1,2,3-Triazole: Synthesis, Conformational Analysis, Glycosidase Inhibitory Activity, Antifungal Assay, and Docking Studies. ACS Omega 2: 7203-18

Chavan SR, Gavale KS, Kamble KM, Pingale SS, Dhavale DD. (2017) gem-Disubstituent Effect in Rate Acceleration of Intramolecular Alkyne-Azide Cycloaddition Reaction. Tetrahedron 73: 365-72

Gavale KS, Chavan SR, Khan A, Joshi R, Dhavale DD. (2015) Azetidine- and N-carboxylic azetidine-iminosugars as amyloglucosidase inhibitors: synthesis, glycosidase inhibitory activity and molecular docking studies. Organic & Biomolecular Chemistry 13: 6634-46


PATENT:

Vijayvitthal Thippannachar Mathad, Pavankumar Vrajlal Solanki, Sekhar Babu Uppelli, Shrawan Ratan Chavan.
A process for the preparation of asenapine and novel salts thereof; 2012; WO2013024492A2


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