Funded by: The National Heart, Lung, and Blood Institute (NHLBI); Grant #: P01HL107151

Shared Resources Core - Carbohydrate Synthesis
Specific Aims:
  • Produce large scale quantities of advanced intermediates required for the production of targeted sialoside ligands.
  • Produce sialoside ligands of siglecs to support projects of the Lung Inflammatory Disease (LID-PEG) program.

Compounds also available to the scientific community for nominal charge to cover costs associated with producing the compounds and shipping.

For more information, please contact the Core Director, Dr. Corwin Nycholat (email: nycholat@scripps.edu).


Sialoside ligands
intermediates in stock (green) or available upon request ( yellow)
Glycan No. Structure Azide Amine Biotinylated PAA (1 MDa) (PEG)-Lipid Lipid
1 1 mg 1 mg 50 ug 50 ug 50 ug 1 mg
2 1 mg 1 mg 50 ug 50 ug 50 ug 1 mg
3 1 mg 1 mg 50 ug 50 ug 50 ug 1 mg
4 1 mg 1 mg 50 ug 50 ug 50 ug 1 mg
5 1 mg 1 mg 50 ug 50 ug 50 ug 1 mg
6 1 mg 1 mg 50 ug 50 ug 50 ug 1 mg
7 1 mg 1 mg 50 ug 50 ug 50 ug 1 mg
8 1 mg 1 mg 50 ug 50 ug 50 ug 1 mg
9 1 mg 1 mg 50 ug 50 ug 50 ug 1 mg
10 1 mg 1 mg 50 ug 50 ug 50 ug 1 mg
11 NA 1 mg 50 ug 50 ug 50 ug 1 mg
12 1 mg 1 mg 50 ug 50 ug 50 ug 1 mg
13 1 mg 1 mg 50 ug 50 ug 50 ug 1 mg
14 1 mg 1 mg 50 ug 50 ug 50 ug 1 mg
15 NA 1 mg 50 ug 50 ug 50 ug 1 mg
16 NA 1 mg 50 ug 50 ug 50 ug 1 mg
17 NA 1 mg 50 ug 50 ug 50 ug 1 mg
18 NA NA 50 ug 50 ug 50 ug 1 mg
20 1 mg 1 mg 50 ug 50 ug 50 ug 1 mg
21 1 mg 1 mg 50 ug 50 ug 50 ug 1 mg
22a NA NA NA NA NA NA
23a NA NA NA NA NA NA
24b NA NA NA NA NA NA

a 50 ug (Reducing sugar)
b Contact for details (CMP-Neu5Gc)

Paulson Laboratory      Created by: Anna