Paulson Laboratory

Sampat Ingale, Ph.D.
 
The Scripps Research Institute
10550 North Torrey Pines Road, MEM-L71
La Jolla, CA 92037
858-784-9636(phone)
858-784-9690 (FAX)
singale@scripps.edu

EDUCATION:

August 2007 - Ph.D. Chemistry, The University of Georgia (USA)

1999 - B.S. Pharmaceutical and Fine Chemicals, Institute of Chemical Technology [aka, UDCT] (India)

1996 - B.S. Chemistry, University of Mumbai (India)



PROFESSIONAL EXPERIENCES:

March 2013 to Present: Research Associate @ The Scripps Research Institute, La Jolla, CA, USA (Advisor: Prof. James C. Paulson)

April 2011 to December 2012: Senior Research Scientist - Global Discovery @ Nycomed Pharma Private Limited (Nycomed: a Takeda company), Andheri, MH, India (Vice-President: Dr. Sham Nikam)

August 2007 to April 2011: Postdoctoral Fellow, Department of Chemistry and Cell Biology @ The Scripps Research Institute, La Jolla, CA, USA (Advisor: Prof. Philip E. Dawson)

August 2002 to August 2007: Doctoral Candidate, Department of Chemistry @ The University of Georgia, Athens, GA, USA (Advisor: Prof. Geert-Jan Boons)

July 1999 to July 2002: Research and Development officer @ The Hindustan Unilever Limited (HUL), Andheri, MH, INDIA



ACADEMIC AND PROFESSIONAL ASSOCIATIONS:

2007-present: American Chemical Society

2002 to present: Mumbai University Institute of Chemical Technology- Alumni Association



PATENTS:

Three Component Carbohydrate Vaccines
Boons, G.J.; Buskas, T.; Ingale, S.; Wolfert, M.
PCT Intl. Appl. (2007, WO2007079448)

Liposome mediated chemical ligation
Ingale, S.; Buskas, T.; Boons, G.J.
PCT Intl Appl. (2007, WO2007146070)



PUBLICATIONS:

Ingale, S., and Dawson, P. E. (2011) On resin side-chain cyclization of complex peptides using CuAAC, Org Lett 13, 2822-2825.

Ingale, S., Gach, J. S., Zwick, M. B., and Dawson, P. E. (2010) Synthesis and analysis of the membrane proximal external region epitopes of HIV-1, J Pept Sci 16, 716-722.

Teo, C. F., Ingale, S., Wolfert, M. A., Elsayed, G. A., Not, L. G., Chatham, J. C., Wells, L., and Boons, G. J. (2010) Glycopeptide-specific monoclonal antibodies suggest new roles for O-GlcNAc, Nat Chem Biol 6, 338-343.

Ingale, S., Wolfert, M. A., Buskas, T., and Boons, G. J. (2009) Increasing the antigenicity of synthetic tumor-associated carbohydrate antigens by targeting Toll-like receptors, Chembiochem 10, 455-463.

Ferrand, Y., Klein, E., Barwell, N. P., Crump, M. P., Jimenez-Barbero, J., Vicent, C., Boons, G. J., Ingale, S., and Davis, A. P. (2009) A synthetic lectin for O-linked beta-N-acetylglucosamine, Angew Chem Int Ed Engl 48, 1775-1779.

Ingale, S., Wolfert, M. A., Gaekwad, J., Buskas, T., and Boons, G. J. (2007) Robust immune responses elicited by a fully synthetic three-component vaccine, Nat Chem Biol 3, 663-667.

Ingale, S., Buskas, T., and Boons, G. J. (2006) Synthesis of glyco(lipo)peptides by liposome-mediated native chemical ligation, Org Lett 8, 5785-5788.

Buskas, T., Ingale, S., and Boons, G. J. (2006) Glycopeptides as versatile tools for glycobiology, Glycobiology 16, 113R-136R.

Buskas, T., Ingale, S., and Boons, G. J. (2005) Towards a fully synthetic carbohydrate-based anticancer vaccine: synthesis and immunological evaluation of a lipidated glycopeptide containing the tumor-associated tn antigen, Angew Chem Int Ed Engl 44, 5985-5988.


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