Selected research articles:

1. Coste B, Xiao B, Santos JS, Syeda R, Grandl J, Spencer KS, Kim SE, Schmidt M, Mathur J, Dubin AE, Montal M, Patapoutian A. (2012) Piezos are pore-forming subunits of mechanically activated channels. Nature, Feb 19. doi: 10.1038/nature10812.

2. Kim SE, Coste B, Chadha A, Cook B, Patapoutian A. (2012) The role of Drosophila Piezo in mechanical nociception. Nature, Feb 19. doi: 10.1038/nature10801.

3. Xiao B, Coste B, Mathur J, Patapoutian A. (2011) Temperature-dependent STIM1 activation induces Ca(2+) influx and modulates gene expression. Nature Chemical Biology, 7:351-8

4. Coste B, Mathur J, Schmidt M, Earley TJ, Ranade S, Petrus MJ, Dubin AE, Patapoutian A. (2010) Piezo1 and Piezo2 are essential components of distinct mechanically-activated cation channels. Science, 330: 55-6

5. Grandl J, Kim SE, Uzzell V, Bursulaya B, Petrus M, Bandell M, Patapoutian A. (2010) Temperature-induced opening of TRPV1 ion channel is stabilized by the pore domain. Nature Neuroscience, 13: 708-14

6. Schmidt M, Dubin A, Petrus M, Earley T, Patapoutian A. (2009) Nociceptive signals induce trafficking of TRPA1 to the plasma membrane. Neuron, 64:498-509

7. Hu H, Bandell M, Petrus MJ, Zhu MX, Patapoutian A. (2009) Zinc activates damage-sensing TRPA1 ion channels. Nature Chemical Biology 5:183-90

8. Grandl J, Hu H, Bandell M, Bursulaya B, Schmidt M, Petrus M, Patapoutian A. (2008) Pore region of TRPV3 ion channel is specifically required for heat-activation. Nature Neuroscience, 11: 1007-13

9. Dhaka A, Murray AN, Mathur J, Earley TJ, Petrus MJ, Patapoutian A. (2007) TRPM8 is Required for Cold Sensation in Mice. Neuron, 54: 371-8

10. Macpherson LJ, Dubin AE, Evans MJ, Marr F, Schultz PG, Cravatt BF, Patapoutian A. (2007) Noxious compounds activate TRPA1 ion channels through covalent modification of cysteines. Nature 445:541-5

11. Bandell M, Dubin AE, Petrus MJ, Orth A, Mathur J, Hwang SW, Patapoutian A. (2006) High-throughput random mutagenesis screen reveals TRPM8 residues specifically required for activation by menthol. Nature Neuroscience, 9:493-500

12. Moqrich A, Hwang SW, Earley TJ, Petrus MJ, Murray AN, Spencer KSR, Andahazy M, Story G, Patapoutian A. (2005) Impaired thermosensation in Mice Lacking TRPV3, a Heat-Sensing channel in skin. Science, 307: 1468-72

13. Bandell M, Story GM, Hwang SW, Viswanath V, Eid SR, Petrus MJ, Earley TJ, Patapoutian A. (2004) Noxious Cold Ion Channel TRPA1 Is Activated by Pungent Compounds and Bradykinin. Neuron, 41:849-57

14. Viswanath V, Story GM, Peier AM, Petrus MJ, Lee VL, Hwang SW, Patapoutian A,* and Jegla T.* (2003) Opposite thermosensor in fruitfly and mouse. Nature, 423: 822-3 (co-corresponding authors)

15. Story GM, Peier AM, Reeve AJ, Eid SR, Mosbacher J, Hricik TR, Earley TJ, Hergarden AC, Andersson DA, Hwang SW, McIntyre P, Bevan S, Patapoutian A. (2003) ANKTM1, a TRP-like channel expressed in nociceptive neurons, is activated by cold temperatures. Cell, 112: 819-829

16. Peier AM, Reeve AJ, Andersson DA, Moqrich A, Earley TJ, Hergarden AC, Story GM, Colley S, Hogenesch JB, McIntyre P, Bevan S, Patapoutian A. (2002) A novel heat-sensitive TRP channel expressed in keratinocytes. Science, 296: 2046-9

17. Peier AM, Moqrich A, Hergarden AC, Reeve AJ, Andersson DA, Story GM, Earley TJ, Dragoni I, McIntyre P, Bevan S, Patapoutian A. (2002) A Trp Channel that Senses Cold Stimuli and Menthol. Cell, 108: 705-715