paegel Lab @ TSRI 130 Scripps Way 1B2 Jupiter, FL



MacConnell AB, Paegel BM (2017) Poisson Statistics of Combinatorial Library Sampling Predict False Discovery Rates of Screening. ACS Combi Sci (in press).

MacConnell AB, Price AK, Paegel BM (2017) An Integrated Microfluidic Processor for DNA-Encoded Combinatorial Library Functional Screening. ACS Combi Sci 19:181.

Mendes K, Malone ML, Ndungu JM, Suponitsky-Kroyer I, Cavett VJ, McEnaney PJ, MacConnell AB, Ronacher K, Stanley K, Utset O, Walzl G, Paegel BM, Kodadek T (2017) High-throughput Identification of DNA-Encoded IgG Ligands that Distinguish Active and Latent Mycobacterium Tuberculosis Infections. ACS Chem Biol 12: 234.

Malone ML, Cavett VJ, Paegel BM (2017) Chemoselective Coupling Preserves the Substrate Integrity of Surface-Immobilized Oligonucleotides for Emulsion PCR-Based Gene Li- brary Construction. ACS Combi Sci 19:9.

Tran DT, Cavett VJ, Dang VQ, Torres, HL, Paegel BM (2016) Evolution of a MS-Grade Protease with PTM-Directed Specificity. Proc Natl Acad Sci USA 113:14686.

Malone ML, Paegel BM (2016) What is a ‘DNA-Compatible Reaction?’ ACS Combi Sci 18: 182.

Price AK, MacConnell AB, Paegel BM (2016) hvSABR: Photochemical Dose-Response Bead Screening in Droplets. Anal Chem 88: 2904.

Price AK & Paegel BM (2016) Discovery in Droplets. Anal Chem 88: 339.

MacConnell AB, McEnaney PJ, Cavett VJ, Paegel BM (2015) DNA-Encoded Solid-Phase Synthesis: Encoding Language Design and Complex Oligomer Library Synthesis. ACS Combi Sci 17: 518.

Price AK, MacConnell AB, Paegel BM (2014) Microfluidic Bead Suspension Hopper. Anal Chem 86: 5039.

Matosevic S, Paegel BM (2013) Layer-by-layer cell membrane assembly. Nat Chem 5: 958.

Matosevic S, Paegel BM (2011) Stepwise synthesis of giant unilamellar vesicles on a microfluidic assembly line. J Am Chem Soc 133:2798.

Paegel BM (2010) Microfluidic landscapes for evolution. Curr Opin Chem Biol 14:568.

Paegel BM, Joyce GF (2010) Microfluidic compartmentalized directed evolution. Chem Biol 17:717.

Paegel BM, Joyce GF (2008) Darwinian evolution on a chip. PLoS Biol 6:900.

Paegel BM, Grover WH, Skelley AM, Mathies RA, Joyce GF (2006) Microfluidic serial dilution circuit. Anal Chem 78:7522.


Paegel BM, Blazej RG, Mathies RA (2003) Microfluidic devices for DNA sequencing: sample preparation and electrophoretic analysis. Curr Opin Biotechnol 14:42.

Paegel BM, Yeung SHI, Mathies RA (2002) Microchip bioprocessor for integrated nanovolume sample purification and DNA sequencing. Anal Chem 74:5092.

Paegel BM, Emrich CA, Wedemayer GJ, Scherer JR, Mathies RA (2002) High throughput DNA sequencing with a microfabricated 96-lane capillary array electrophoresis bioprocessor. Proc Natl Acad Sci USA 99:574.

Paegel BM, Hutt LD, Simpson PC, Mathies RA (2000) Turn geometry for minimizing band broadening in microfabricated capillary electrophoresis channels. Anal Chem 72:3030.