Vol 6. Issue 18 / May 22, 2006

The Graduating Students

The 31 individuals who are graduating from The Scripps Research Institute's Kellogg School of Science and Technology this week are listed below, with the names of their advisors and thesis titles.

 

Shannon Marie Biros

Part I. Design and Synthesis of Alpha-Helix Peptidomimetics using Inverse Electron Demand Diels-Alder Reactions
Part II. Structure and Binding Properties of a Deep, Water-soluble Cavitand

Advisor: Julius Rebek, Jr., Ph.D., Professor, Department of Chemistry


Daniel A. Calarese

Structural Studies of HIV-1 Neutralizing Antibody 2G12

Advisor: Ian A. Wilson, D.Phil., Professor, Department of Molecular Biology


Kevin John Capps

Part I.  Synthesis and Application of Solution-Phase Combinatorial Libraries 
Part II. Synthesis of GAR Tfase Inhibitors

Advisor: Dale L. Boger, Ph.D., Professor, Department of Chemistry


M. Rocio A. Carrera

Immunopharmacotherapy: Vaccines for the Treatment of the Health and Social Hazards of Drug Abuse

Advisor:  Kim D. Janda, Ph.D., Professor, Department of Chemistry


Cheng-yuen Huang

The Development of Carbohydrate Based Vaccine

Advisor: Chi-Huey Wong, Ph.D., Professor, Department of Chemistry


Brendan M. Crowley

I. Total Synthesis of the Ristocetin Aglycon 
II. Total and Semisynthetic Analogs of the Vancomycin Aglycon Effective against Vancomycin Resistant Bacteria

Advisor:  Dale L. Boger, Ph.D., Professor, Department of Chemistry


Theodore R. Foss

Studies on the Quaternary Structure, Dissociation Pathway and Ligand Binding Propeiries of the Amyloidogenic Transthyretin

Advisor: Jeffery W. Kelly, Ph.D., Professor, Department of Chemistry


Lu Gan

Conformational and Covalent Control of Bacteriophage HK97 Capsid Expansion

Advisor:  John R. Johnson, Ph.D., Professor, Department of Molecular Biology


Peter Jesse Gaskill

A Study in the Role of Virus Based Changes in HIV on the Development of Neuro AIDS

Advisor:  Howard S. Fox, M. D., Ph.D., Associate Professor, Department of Molecular & Integrative Neurosciences


James J. Graziano

A Novel System for the Creation and Screening of de novo Proteins from Libraries of Randomly Shuffled Secondary Structure Fragments   

Advisor: Peter Schultz, Ph.D., Professor, Department of Chemistry


Stephanie L. Gupton

The Segregation of the Actin Cytoskeleton into Functional Modules in Migrating Epithelial Cells

Advisor:  Clare M. Waterman-Storer, Ph.D., Associate Professor, Department of Cell Biology


Olgun Guvench

Theoretical Studies of Proteins and Protein-Ligand Complexes

Advisor:  Charles L. Brooks, III, Ph.D., Professor, Department of Molecular Biology


William Seth Horne

Structure and Function in Peptide-Based Supramolecular Designs

Advisor:  M. Reza Ghadiri, Ph.D., Professor, Department of Chemistry


Steven M. Johnson

The Design, Synthesis, and Biophysical Evaluation of Small Molecules to Study and Selectively Inhibit Transthyretin Amyloidosis

Advisor: Jeffery W. Kelly, Ph.D., Professor, Department of Chemistry


David B. Kastrinsky

Asymmetric Synthesis of CBI and the Total Synthesis and Structure Revision of (+)-Yatakemycin

Advisor: Dale L. Boger, Ph.D., Professor, Department of Chemistry


Jamie Michelle Keck

The Effects of Cyclin E Deregulation on Mitosis

Advisor: Steven I. Reed, Ph.D., Professor, Department of Molecular Biology


Lucas J. Leman

Accelerating Aminoacyl Transfer in Water Using Simple Prebiotic Molecules and Rationally Designed Peptides

Advisor:  M. Reza Ghadiri, Ph.D., Professor, Department of Chemistry


Warren G. Lewis

Bio/Click Catalysis: Azide-Aklyne [3+2] Cycloaddition and Cholinergic Chemistry

Advisor: M. G. Finn, Ph.D., Professor, Department of Chemistry


Fu-Sen Liang

Targeting Biomacromolecules by Aminoglycosides

Advisor: Chi-Huey Wong, Ph.D., Professor, Department of Chemistry


Fei Liu

CD8+ T cell Response to Lymphocytic Choriomeningitis Virus Infection

Advisor:  J. Lindsay Whitton, M.D., Ph.D., Professor, Department of Molecular & Integrative Neurosciences


Jonathan Scott Melnick

Chemistry and Biology of the Tyrosine Kinome

Advisor: Peter Schultz, Ph.D., Professor, Department of Chemistry


Jason A. Moss

Peptide Synthesis Methodology and Application Toward the Study of Naturally-Occurring Biomacromolecules

Advisor:  Kim D. Janda, Ph.D., Professor, Department of Chemistry


Byron Willis Purse

Structure and Reactivity in the Inner Space of Host Molecules

Advisor: Julius Rebek, Jr., Ph.D., Professor, Department of Chemistry


Jason M. Rohde

Synthetic Approaches to Aplydactone and Chartellamide A Inspired by Biosynthetic Hypotheses

Advisor: Erik J. Sorensen, Ph.D.


Anupama R. Sawkar

Chemical Chaperones Increase the Cellular Activity of Glucocerebrosidase Variants: A Therapeutic Strategy for Gaucher Disease

Advisor: Jeffery W. Kelly, Ph.D., Professor, Department of Chemistry


Desiree A. Thayer

Effects of Glycans on Peptide Antibiotics and Analytical Methods for Carbohydrate Sequencing and Binding Interactions

Advisor: Chi-Huey Wong, Ph.D., Professor, Department of Chemistry


Ian F. Thorpe

Probing the Relationship between Structure, Function and Dynamics in Proteins

Advisor:  Charles L. Brooks, III, Ph.D., Professor, Department of Molecular Biology


Douglass Wu

The Design and Synthesis of Glycolipids for CD1d-mediated Natural Killer T-cell Activation

Advisor: Chi-Huey Wong, Ph.D., Professor, Department of Chemistry


Peng Wu

Metal Mediated Synthesis of Heterocycles and Dendrimers

Advisor: K. Barry Sharpless, Ph.D., Professor, Department of Chemistry


Jianming Xie

Adding Unnatural Amino Acids to the Genetic Repertoire

Advisor: Peter Schultz, Ph.D., Professor, Department of Chemistry


Mark Edward Zak

The Total Synthesis of Thiostrepton

Advisor: K. C. Nicolaou, Ph.D., Professor and Chair, Department of Chemistry


     

Send comments to: mikaono[at]scripps.edu