Antigen-Binding Site of Anti-HIV Antibody 4E10

The footprint (purple) of the peptide epitope (yellow) is shown on the molecular surface of the antibody. Image by Rosa Cardoso generated with Grasp and Molscript.

Overall View of the Fab 4E10-Peptide Epitope Complex.

The antibody light (green) and heavy (purple) chains and the peptide (orange) are illustrated with the ribbon representation. CDRs L1, L3, H1, H2, and H3 contact the epitope. Image by Rosa Cardoso generated with Molscript.