The Graduating Students

Here are the individuals who make up The Scripps Research Institute’s (TSRI) graduating class of 2001, their thesis titles, and their advisors.

 


Danuta Balicki, M.D.

Gene Transfer Mediated by Histone H2A

Advisor: Ernest Beutler, professor and chairman,
Department of Molecular and Experimental Medicine


Christopher N. C. Boddy

Synthesis of the Diaryl Ethers of Vancomycin: Controlling Sterogenic Axes

Advisor: K. C. Nicolaou, professor and chairman,
Department of Chemistry


Dennis T.Y. Bong

Part I. Mechanistic Insights into Nodaviral Transfection
Part II. Directing Peptide Self-Assembly

Advisor: M. Reza Ghadiri, professor, Department of Chemistry and Molecular Biology

 


Steven L. Castle

Total Synthesis of the Vancomycin Aglycon and Related Compounds

Advisor: Dale L. Boger, professor,
Department of Chemistry

 

 


Phyllis Frosst

Localization and Function of Tpr, a Component of the Nuclear Pore Complex

Advisor: Larry Gerace, professor,
Department of Cell Biology

 


Joel Goldberg

Part I. Solvolysis Regioselectivity and X-Ra Structure of the Duocarmycin SA Alkylation Subunit
Part II. Solution Phase Synthesis of Compound Libraries Targeting the Erythropoietin Receptor
Part III. Identification of a New Class of Angiogenesis Inhibitors which Function by Blocking the Interaction of Proteinase MMP2 and Integrin avb3

Advisor: Dale L. Boger, professor,
Department of Chemistry


David J. Hosfield

Structural Studies of Two Archetypical DNA Repair Enzymes and their DNA Complexes

Advisor: John A. Tainer, professor,
Department of Molecular Biology


Kinya Hotta

Structural Insight into a Decarboxylase Antibody

Advisor:Ian A. Wilson, professor,
Department of Molecular Biology


Kathryn M. Koeller

Chemical and Enzymatic Synthesis of Oligovalent Carbohydrate, Glycopeptide, and Aminoglycoside Recognition Elements: Multivalency in Natural and Synthetic Glycoconjugate Structure

Advisor: Chi-Huey Wong, professor,
Department of Chemistry


Nicole Kresge

Sex at the Molecular Level: The Crystal Structures of Abalone Fertilization Proteins

Advisor:C. David Stout, associate professor,
Department of Molecular Biology


Ryan S. Littlefield

Regulation of Thin Filament Length in Striated Muscle

Advisor: Velia M. Fowler, professor,
Department of Cell Biology

 


Satchidananda Panda

TEJ Defines a Role for Poly (ADP-Ribosyl)ation in Establishing Period Length of the Arabidopsis Circadian Oscillator

Advisor: Steve A. Kay, professor,
Department of Cell Biology


Matthew P. Patricelli

Biochemical and Physiological Investigations of Fatty Acid Amide Hydrolase

Advisor: Benjamin F. Cravatt, assistant professor,
Departments of Cell Biology and Chemistry


H. Michael Petrassi

Design and Synthesis of Inhibitors of Transthyretin Amyloid Fibril Formation

Advisor: Jeffery W. Kelly, professor,
Department of Chemistry

 


Christopher D. Putnam

Structural Basis for Four Pardigmatic Defenses Preventing DNA Damage in the Cell

Advisor: John A. Tainer, professor,
Department of Molecular Biology

 


Erica Ollmann Saphire

Crystal Structure of an Intact Human IgG: Implications for HIV-1 Neutralization and Effector Function

Advisor: Ian A. Wilson, professor,
Department of Molecular Biology

 


Allen A. Thomas

I. Aminohydroxylation of Unsaturated Phosphonates: A Template for Molecular Diversity
II. Rapid Discoveries in 0smium (VIII) Catalysis Using Automation and Mass Spectrometry

Advisor: K. Barry Sharpless, professor,
Department of Chemistry


Jonathan D. Toker

Discovery and Exploration of an Antibody- Catalyzed Asymmetric 1, 3-Dipolar

Advisor: Kim D. Janda, professor,
Departments of Chemistry and Molecular Biology


Vickie Tsui

NMR Restraints and Solvent Models in Molecular Dynamics Simulations: Effects on Biomolecular Structure and Intermolecular Interactions

Advisor: David A. Case, professor,
Department of Molecular Biology

 


Jacques T. Weissman

Regulation of Mammalian Cargo ER Export

Advisor: William E. Balch, professor,
Department of Cell Biology

 


Yohei Yokobayashi

Catalytic and Autocatalytic Peptide Networks

Advisor: M. Reza Ghadiri, professor,
Department of Chemistry and Molecular Biology


 

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