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Scientific Report 2008


Chemistry





Chairman's Overview

Staff

K.C. Nicolaou, Ph.D.*
Chairman
Aline W. and L.S. Skaggs Professor of Chemical Biology
Darlene Shiley Chair in Chemistry

Dariush Ajami, Ph.D.
Assistant Professor of Molecular Assembly

Phil S. Baran, Ph.D.
Professor

Dale L. Boger, Ph.D.*
Richard and Alice Cramer Professor of Chemistry

Tobin J. Dickerson, Ph.D.
Assistant Professor

Sheng Ding, Ph.D.
Associate Professor

Albert Eschenmoser, Ph.D.*
Professor

M.G. Finn, Ph.D.*
Professor

Valery Fokin, Ph.D.
Associate Professor

M. Reza Ghadiri, Ph.D.*
Professor

William A. Greenberg, Ph.D.
Assistant Professor of Chemistry

Inkyu Hwang, Ph.D.
Assistant Professor

Kim D. Janda, Ph.D.**
Professor
Ely R. Callaway, Jr., Chair in Chemistry
Director, Worm Institute of Research and Medicine

Gunnar Kaufmann, Ph.D.
Assistant Professor of Chemistry

Jeffery W. Kelly, Ph.D.*
Lita Annenberg Hazen Professor of Chemistry

Ramanarayanan Krishnamurthy, Ph.D.
Associate Professor

Lucas J. Leman, Ph.D.
Assistant Professor of Chemistry

Richard A. Lerner, M.D.***
President, The Scripps Research Institute
Lita Annenberg HazenProfessor of Immunochemistry
Cecil H. and Ida M. Green Chair in Chemistry

Roy Periana, Ph.D.*****
Professor

Evan T. Powers, Ph.D.
Associate Professor of Chemistry

Julius Rebek, Jr., Ph.D.*
Professor
Director, The Skaggs Institute for Chemical Biology

Edward Roberts, Ph.D.
Professor

Floyd E. Romesberg, Ph.D.
Associate Professor

William Roush, Ph.D.*****
Professor

Peter G. Schultz, Ph.D.*
Professor
Scripps Family Chair

K. Barry Sharpless, Ph.D.*
W.M. Keck Professor of Chemistry

Anita D. Wentworth, Ph.D.
Assistant Professor

Paul Wentworth, Jr., Ph.D.
Professor

Chi-Huey Wong, Ph.D.*
Professor of Chemistry

Jin-Quan Yu, Ph.D.
Associate Professor

(Andrew) Bin Zhou, Ph.D.
Assistant Professor of Immunochemistry



SENIOR SCIENTIST

Luis Martinez, Ph.D.*****

Staff Scientists


Lisa Eubanks, Ph.D.

Rajesh Grover, Ph.D.

Sarah Hanson, Ph.D.

Lubica Supekova, Ph.D.

Wen Xiong, Ph.D.

Instrumentation/service Facilities

Raj K. Chadha, Ph.D.
Director, X-ray Crystallography Facility

Dee H. Huang, Ph.D.
Director, Nuclear Magnetic Resonance Facility

Gary E. Siuzdak, Ph.D.
Senior Director, Mass Spectrometry Facility



Senior Research Associate

Suresh Pitram, Ph.D.

Research Associates

Ramzey Abujarour, Ph.D.

Rajesh Ambasudhan, Ph.D.

Manuel Amorin Lopez, Ph.D.

Mark Ams, Ph.D.

Yoshio Ando, Ph.D.

Deepshikha Angrish, Ph.D.

Shinji Ashida, Ph.D.

Micahel Baksh, Ph.D.

Deboshri Banerjee, Ph.D.

Elizabeth Barrett, Ph.D.****

Roland Barth, Ph.D.*****

Clay Bennett, Ph.D.

Moritz Biskup, Ph.D.
Universität Karlsruhe
Karlsruhe, Germany

Anthony Boitano, Ph.D.
Genomics Institute of the Novartis Foundation
San Diego, California

Laure Bouchez, Ph.D.

Kristopher Boyle, Ph.D.

Christopher Burke, Ph.D

Antonio Burtoloso, Ph.D.
University of Sao Paulo
Sao Paulo, Brazil

Mark Bushey, Ph.D.
Exxon, Inc.
Union City, New Jersey

Darren Bykowski, Ph.D.*****

Petr Capek, Ph.D.

Katerina Capkova, Ph.D.

Arani Chanda, Ph.D.

Ke Chen, Ph.D.

Peng Chen, Ph.D.

Govardhan Cherukupalli, Ph.D.
Epix Pharmaceuticals
Lexington, Massachusetts

Jodie Chin, Ph.D.

Srinivas Reddy Chirapu, Ph.D.

Chandramouli Chiruta, Ph.D.

Dong-Gyu Cho, Ph.D.

So-Hye Cho, Ph.D.

Sungwook Choi, Ph.D.

Joyanta Choudhury, Ph.D.

Sarwat Chowdhury, Ph.D.

Stepan Chuprakov, Ph.D.

Petr Cigler, Ph.D.

T. Ryan Cirz
Achaogen
South San Francisco, California

Scott Cockroft, Ph.D.
University of Edinburgh
Edinburgh, Scotland

David Colby, Ph.D.
Purdue University
West Lafayette, Indiana

Kevin Cole, Ph.D.
Eli Lilly and Company
Indianapolis, Indiana

Christine Crane, Ph.D.

Matthew Cremeens, Ph.D.
Gonzaga University
Redmond, Washington

Fernando Rodrigo Pinacho Crisostomo, Ph.D.
Burnham Institute for Medical Research
La Jolla, California

Jeffrey Culhane, Ph.D.

Stephen Dalby, Ph.D.

Etzer Darout, Ph.D.
Pfizer Inc.
Groton, Connecticut

Amy DeBaillie, Ph.D.
Eli Lilly and Company
Indianapolis, Indiana

Judith Denery, Ph.D.

Ross Denton, Ph.D.
University of Cambridge
Cambridge, England

Caroline Desponts, Ph.D.

Antonia Di Mola, Ph.D.

Deguo Du, Ph.D.

Anna Dubrovska, Ph.D.

Viktoriya Dubrovskaya, Ph.D.

Joshua Dunetz, Ph.D.
Pfizer Inc.
Groton, Connecticut

Kyle Eastman, Ph.D.

David Edmonds, Ph.D.

Jem Efe, Ph.D.

Jan Elsner, Ph.D.
Celgene Pharmaceuticals
San Diego, California

Daniel Ess, Ph.D.

Cyrine Ezzili, Ph.D.

Xingang Fang, Ph.D.

Simon Ficht, Ph.D.
Sanofi-Aventis Deutschland GmbH
Frankfurt, Germany

Joseph Rodolph Fotsing, Ph.D.
Senomyx, Inc.
San Diego, California

Bozena Frackowiak, Ph.D.
Politechnika Opolska
Opole, Poland

Graeme Freestone, Ph.D.
Metabasis Therapeutics, Inc.
San Diego, California

Yu Fu, Ph.D.

Amelia Fuller, Ph.D.
Santa Clara University
Santa Clara, California

Jianmin Gao, Ph.D.
Boston College
Chestnut Hill, Massachusetts

Haibo Ge, Ph.D.

Savvas Georgiades, Ph.D.****

Ola Ghoneim, Ph.D.
Qatar University
Doha, Qatar

Nathan Gianneschi, Ph.D.
University of California
San Diego, California

Cristina Gil-Lamaignere, Ph.D.
University Hospital Nuestra Señora de la Candelaria
Santa Cruz de Tenerife, Spain

Rodolfo Gonzalez, Ph.D.

Scott Grecian, Ph.D.

Neil Grimster, Ph.D.

Rajesh K. Grover, Ph.D.

Jan Grunewald, Ph.D.

Tanja Gulder, Ph.D.

Richard Guy, Ph.D.****

Masaki Handa, Ph.D.
Sagami Chemical Research Center
Ayase, Kanagawa, Japan

Yuanjun He, Ph.D.

Jason Hein, Ph.D.

Dube Henry, Ph.D.

Marcos Hernandez, Ph.D.

Par Holmberg, Ph.D.
Memorial Sloan Kettering Cancer Center
New York, New York

Wen-Xu Hong, Ph.D.

Zhangyong Hong, Ph.D.

Richard J. Hooley, Ph.D.
University of California
Riverside, California

Tamara Hopkins, Ph.D.
Boehringer Ingelheim Pharmaceuticals, Inc.
Ridgefield, Connecticut

Allen Horhota, Ph.D.

Tony Horneff, Ph.D.

Jun-Li Hou, Ph.D.

Claas Hovelmann, Ph.D.

Fang Hu, Ph.D.
Department of Molecular Biology, Scripps Research

Xiaoyi Hu, Ph.D.

Zheng-Zheng Huang, Ph.D.
DuPont Central Research and Development
Wilmington, Delaware

Ben Hutchins, Ph.D.

Der-ren Hwang, Ph.D.
Academia Sinica
Taipei, Taiwan

Giltae Hwang, Ph.D.

Michael Jahnz, Ph.D.
NOXXON Pharma AG
Berlin, Germany

Rong Jiang, Ph.D.*****

Guo Jiantoa, Ph.D.

Hiroyuki Kakei, Ph.D.
Takeda Pharmaceutical Company Limited
Osaka, Japan

Jaroslaw Kalisiak, Ph.D.

Seiji Kamioka, Ph.D.

Moumita Kar, Ph.D.

Kwang Mi Kim, Ph.D.

F. Scott Kimball, Ph.D.

Jeremy Kister, Ph.D.

Keith Korthals, Ph.D.

Larisa Krasnova, Ph.D.

Arkady Krasovskiy, Ph.D.

Luke Lairson, Ph.D.

Jae Wook Lee, Ph.D.

Jinq-Chyi Lee, Ph.D.
National Health Research Institutes
Miaoli County, Taiwan

Jong Seok Lee, Ph.D.

Ki-Bum Lee, Ph.D.
Rutgers University
Piscataway, New Jersey

Sejin Lee, Ph.D.
SK Drug Development Center
Daejong, Korea

Alexandre Lemire, Ph.D.****

Edward Lemke, Ph.D.

Christophe Letondor, Ph.D.****

Chuang-Chuang Li, Ph.D.
Peking University
Peking, China

Fangzheng Li, Ph.D.*****

Hongming Li, Ph.D.
Schering-Plough
Kenilworth, New Jersey

Ke Li, Ph.D.
DuPont Central Research and Development
Wilmington, Delaware

Pi-Hui Liang, Ph.D.
Academia Sinica
Taipei, Taiwan

Yeon-Hee Lim, Ph.D.
Schering-Plough
Kenilworth, New Jersey

Tongxiang Lin, Ph.D.

Troy Lister, Ph.D.
Novartis
Cambridge, Massachusetts

Christopher Liu, Ph.D.
Cubix Pharmaceuticals
Lexington, Massachusetts

Wenshe Liu, Ph.D.
Texas A&M University
College Station, Texas

Michael Luzung, Ph.D.

Utpal Majumder, Ph.D.

Sreeman Mamidyala, Ph.D.

Takeshi Masuda, Ph.D.

Michael Maue, Ph.D.
Bayer CropScience AG
Monheim, Germany

Alexander Mayorov, Ph.D.

Charles Melancon, Ph.D.

Lionel Moisan, Ph.D.
CEA
Gif-Sur-Yvette, France

Ana Montero, Ph.D.****

Miguel Morales, Ph.D.

Adam Morgan, Ph.D.
Concert Pharmaceuticals, Inc.
Lexington, Massachusetts

Ting-Wei Mu, Ph.D.

S. Vasudeva Naidu, Ph.D.

Yuya Nakai, Ph.D.

Joonwoo Nam, Ph.D.
CytRx Corporation
San Diego, California

Tae-Gyu Nam, Ph.D.

Andrew Nguyen, M.D., Ph.D.

Romain Noel, Ph.D.

George Nora, Ph.D.*****

Severin Odermatt, Ph.D.****

Christian Olsen, Ph.D.

Yazmin Osornio, Ph.D.****

Junguk Park, Ph.D.

Nitin Patil, Ph.D.

Johan Paulsson, Ph.D.

Richard Payne, Ph.D.
University of Sydney
Sydney, Australia

Xuemei Peng, Ph.D.****

Murali Peram Surakattula, Ph.D.
CytRx Corporation
San Diego, California

Roshan Perera, Ph.D.
University of Texas
Austin, Texas

Ramulu Poddutoori, Ph.D.

Jonathan Pokorski, Ph.D.

Agustì Lledó Ponsati, Ph.D.

Daniela Radu, Ph.D.
DuPont Central Research and Development
Wilmington, Delaware

Ronald Rahaim, Ph.D.*****

Praveen Rao, Ph.D.
University of Waterloo
Waterloo, Ontario, Canada

Per Restorp, Ph.D.

Kimberly Reynolds, Ph.D.

Jin-Kyu Rhee, Ph.D.

Fatima Rivas, Ph.D.

Joshua Roth, Ph.D.*****

Troy Ryba, Ph.D.
Broad Institute of MIT and Harvard
Cambridge, Massachusetts

Youngha Ryu, Ph.D.
Texas Christian University
Fort Worth, Texas

Catherine Saccavini, Ph.D.

Nicholas Salzameda, Ph.D.

Antonio Sanchez-Ruiz, Ph.D.

Yoshikazu Sasaki, Ph.D.

Stefan Schiller, Ph.D.

Niklas Schone, Ph.D.

Michael Schramm, Ph.D.
California State University
Long Beach, California

Young Jun Seo, Ph.D.

Edward Sessions, Jr., Ph.D.

Shigeki Seto, Ph.D.

Mary Jo Sever, Ph.D.

Alex Shaginian, Ph.D.
Ardea Biosciences
San Diego, California

David Shaw, Ph.D.

Weijun Shen, Ph.D.

Xiao Shengxiong, Ph.D.

Bingfeng Shi, Ph.D.

Yan Shi, Ph.D.

Hiroki Shigehisa, Ph.D.

Hiroyuki Shimamura, Ph.D.

Siddhartha Shenoy, Ph.D.

Ryan Simkovsky, Ph.D.

Chinnappan Sivasankar, Ph.D.****

Michael Smolinski, Ph.D.
Kinex Pharmaceuticals
Buffalo, New York

Xinyi Song, Ph.D.

Simon Stamm, Ph.D.

Sebastian Steiniger, Ph.D.

Antonia Stepan, Ph.D.

James Stover, Ph.D.

Bernhard Stump, Ph.D.

Shun Su, Ph.D.

Hui Kai Sun, Ph.D.*****

Shinobu Takizawa, Ph.D.

Adam Talbot, Ph.D.
Institute of Chemical and Engineering Sciences
Jurong Island, Singapore

Annie Tam, Ph.D.

Yefeng Tang, Ph.D.

Mariola Tortosa, Ph.D.
Instituto de Quimica Organica, CSIC
Madrid, Spain

Craig Turner, Ph.D.****

Matthew Tremblay, Ph.D.

Vincent Trepanier, Ph.D.
Institute of Chemical and Engineering Sciences
Jurong Island, Singapore

Jonathan Tripp, Ph.D.

Meng-Lin Tsao, Ph.D.
University of California
Merced, California

Andrew Udit, Ph.D.

Taiki Umezawa, Ph.D.
Hokkaido University
Sapporo, Japan

Kenji Usui, Ph.D.
Tokyo Institute of Technology
Tokyo, Japan

Carlos Valdez, Ph.D.
Rigel Pharmaceuticals, Inc.
South San Francisco, California

Punna Venkateshwarlu, Ph.D.

Feng Wang, Ph.D.

Jian Wang, Ph.D.

Jiangyun Wang, Ph.D.
Institute of Biophysics
Beijing, China

Lin Wang, Ph.D.

Sheng-Kai Wang, Ph.D.

Weidong Wang, Ph.D.

Xisheng Wang, Ph.D.

Yajuan Wang, Ph.D.

Yuanhua Wang, Ph.D.

Timo Weide, Ph.D.

Albert Willis, Ph.D.
Pharmagra Labs, Inc.
Brevard, North Carolina

Tao Wu, Ph.D.
Institute of Chemical and Engineering Sciences
Jurong Island, Singapore

Heiko Wurdak, Ph.D.

Jian Xie, Ph.D.

Wen Xiong, Ph.D.

Yue Xu, Ph.D.

Junichiro Yamaguchi, Ph.D.

Ryu Yamasaki, Ph.D.
Tokyo University of Science
Tokyo, Japan

Ura Yasuyuki, Ph.D.
Nara Women's University
Nara, Japan

Yan Yin, Ph.D.

Ian Young, Ph.D.

Zhanqian Yu, Ph.D.

Xu Yuan, Ph.D.

Weiqiang Zhan, Ph.D.

Hongjun Zhang, Ph.D.

Xuejun Zhang, Ph.D.

Yanghui Zhang, Ph.D.

Yingchao Zhang, Ph.D.
Hoffmann-La Roche, Inc.
Nutley, New Jersey

Heyue Zhou, Ph.D.

Hongyan Zhou, Ph.D.

Shoutian Zhu, Ph.D.

Joerg Zimmermann, Ph.D.

Visiting Investigators

Keisuke Fukuchi, Ph.D.
Sankyo Co., Ltd.
Tokyo, Japan

Christine Hernandez, Ph.D.
University of Philippines
Diliman, Philippines

(Edmond) Shie-Liang Hsieh, Ph.D.
National Yang-Ming University
Taipei, Taiwan

Masakazu Imamura, Ph.D.
Astellas Pharma Inc.
Tsukuba, Ibaraki, Japan

Kuniyuki Kishikawa, Ph.D.
Kyowa Hakko Kogyo Co., Ltd.
Sunto-gun, Shizuoka, Japan

Michael Meijler, Ph.D.
Ben-Gurion University of the Negev
Be'er Sheva, Israel

Takayoshi Suzuki, Ph.D.
Nagoya City University
Nagoya, Japan

Yoshiyuki Yoneda, Ph.D.
Daiichi Pharmaceutical Co., Ltd.
Tokyo, Japan

 

Scientific Associate


Jon Ashley

* Joint appointment in The Skaggs Institute for Chemical Biology
** Joint appointments in The Skaggs Institute for Chemical Biology and the Department of Immunology and Microbial Science
*** Joint appointments in The Skaggs Institute for Chemical Biology and the Department of Molecular Biology
**** Appointment completed
***** Scripps Florida
Appointment completed; new location shown

 


A chiral catalyst for enantioselective carbon-hydrogen activation. Work done in the laboratory of Jin-Quan Yu, Ph.D., associate professor. To see a larger image, click here.



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