Scientific Report 2007

Molecular Biology

Chairman's Overview

Staff

Peter E. Wright, Ph.D.*
Professor and Chairman
Cecil H. and Ida M. Green Investigator in Medical Research

Ruben Abagyan, Ph.D.
Professor

Carlos F. Barbas III, Ph.D.**
Professor
Janet and W. Keith Kellogg II Chair, Molecular Biology

Rajesh Belani, Ph.D.
Adjunct Assistant Professor
Scripps Mercy Hospital
San Diego, California

Ola Blixt, Ph.D.
Assistant Professor of Molecular Biology

Michael N. Boddy, Ph.D.
Assistant Professor

Charles L. Brooks III, Ph.D.
Professor

David A. Case, Ph.D.
Professor

Geoffrey Chang, Ph.D.*
Associate Professor

Eli Chapman, Ph.D.
Assistant Professor of Molecular Biology

Jerold Chun, M.D., Ph.D.
Professor

Aymeric Pierre De Parseval, Ph.D.***
Assistant Professor of Molecular Biology
Public Health Research Institute
Newark, New Jersey

Lluis Ribas De Pouplana, Ph.D.
Adjunct Assistant Professor
Barcelona Science Park
Barcelona, Spain

Ashok Deniz, Ph.D.
Associate Professor

H. Jane Dyson, Ph.D.
Professor

John H. Elder, Ph.D.****
Professor

Martha J. Fedor, Ph.D.*
Associate Professor

James A. Fee, Ph.D.
Professor of Research

Elizabeth D. Getzoff, Ph.D.*****
Professor

David B. Goodin, Ph.D.
Associate Professor

David S. Goodsell Jr., Ph.D.
Associate Professor of Molecular Biology

Joel M. Gottesfeld, Ph.D.
Professor

Jennifer Harris, Ph.D.
Assistant Professor of Biochemistry

Christian A. Hassig, Ph.D.
Adjunct Assistant Professor
Kalypsis, Inc.
San Diego, California

Peter B. Hedlund, M.D., Ph.D.
Assistant Professor of Molecular Biology

John E. Johnson, Ph.D.
Professor

Gerald F. Joyce, M.D., Ph.D.**
Professor
Dean, Faculty

Ehud Keinan, Ph.D.
Adjunct Professor
Technion-Israel Institute of Technology
Haifa, Israel

Richard A. Lerner, M.D., Ph.D.**
President, Scripps Research
Lita Annenberg Hazen Professor of Immunochemistry
Cecil H. and Ida M. Green Chair in Chemistry

Scott Lesley, Ph.D.
Assistant Professor of Biochemistry

Tianwei Lin, Ph.D.
Assistant Professor

Ian MacRae, Ph.D.
Assistant Professor

Clare McGowan, Ph.D.^†
Associate Professor

Duncan E. McRee, Ph.D.
Adjunct Associate Professor
ActiveSight
San Diego, California

David P. Millar, Ph.D.
Associate Professor

Louis Noodleman, Ph.D.
Associate Professor

Arthur J. Olson, Ph.D.
Professor

James C. Paulson, Ph.D.^††
Professor

Vijay Reddy, Ph.D.
Associate Professor

Steven I. Reed, Ph.D.^†
Professor

Paul Russell, Ph.D.^†
Professor

Michel Sanner, Ph.D.
Associate Professor

Harold Scheraga, Ph.D.
Adjunct Professor
George W. and Grace L. Todd Professor of Chemistry, Emeritus
Cornell University
Ithaca, New York

Paul R. Schimmel, Ph.D.**
Ernest and Jean Hahn Professor of Molecular Biology and Chemistry

Anette Schneemann, Ph.D.
Associate Professor

Subhash C. Sinha, Ph.D.*
Associate Professor of Medicinal Chemistry

Gary Siuzdak, Ph.D.
Adjunct Associate Professor
Director, Center for Mass Spectrometry

Vaughn V. Smider, Ph.D.
Assistant Professor of Molecular Biology

Robyn L. Stanfield, Ph.D.
Assistant Professor

James Stevens, Ph.D.***
Assistant Professor
Centers for Disease Control and Prevention
Atlanta, Georgia

Raymond C. Stevens, Ph.D.^†††
Professor

Charles D. Stout, Ph.D.
Associate Professor

Peiqing Sun, Ph.D.
Associate Professor

J. Gregor Sutcliffe, Ph.D.
Professor

John A. Tainer, Ph.D.*
Professor

Fujie Tanaka, Ph.D.
Associate Professor

Elizabeth A. Thomas, Ph.D.
Assistant Professor

James R. Williamson, Ph.D.*****
Professor
Associate Dean, Kellogg School of Science and Technology

Ian A. Wilson, D.Phil.*
Professor

Curt Wittenberg, Ph.D.^†
Professor

Kurt Wüthrich, Ph.D.
Cecil H. and Ida M. Green Professor of Structural Biology

Xiang-Lei Yang, Ph.D.
Assistant Professor of Molecular Biology

Todd O. Yeates, Ph.D.
Adjunct Professor
University of California
Los Angeles, California

Qinghai Zhang, Ph.D.
Assistant Professor

Service Facilities

John Chung, Ph.D.***
Manager, Nuclear Magnetic Resonance Facilities
Juniper Networks, Inc.
Sunnyvale, California

Gerard Kroon
Manager, Nuclear Magnetic Resonance Facilities

Bo Ma, Ph.D.
Core Manager, Consortium for Functional Glycomics

Michael E. Pique
Director, Computer Graphics Development

Nahid Razi, Ph.D.
Assistant Core Manager, Consortium for Functional Glycomics

Peter Sobieszcsuk, Ph.D.^††††
Core Manager, Consortium for Functional Glycomics

Senior Staff Scientist

Quansheng Zhou, Ph.D.

Staff Scientists

Svitlana Berezhna, Ph.D.

Reto Horst, Ph.D.

Ying Chuan Lin, Ph.D.

Maria Martinez-Yamout, Ph.D.

Garrett M. Morris, Ph.D.

Chiaki Nishimura, Ph.D.

Jeffrey Speir, Ph.D.

Mutsuo Yamaguchi, Ph.D.

Xueyong Zhu, Ph.D.

Senior Research Associates

David Barondeau, Ph.D.***
Texas A&M University
College Station, Texas

Kirk Beebe, Ph.D.***
Metabolon, Inc.
Durham, North Carolina

Ryan Burnett, Ph.D.

Zhongguo Chen, Ph.D.^††††

Adrienne Elizabeth Dubin, Ph.D.

Li Fan, Ph.D.

Maria Alejandra Gamez-Abascal, Ph.D.

Elsa Garcin, Ph.D.

Julio Kovacs, Ph.D.

Kelly Lee, Ph.D.

Richard R. Rivera, Ph.D.

Kenji Sugase, Ph.D.***
Suntory Institute for Bioorganic Research
Osaka, Japan

Philip Arno Venter, Ph.D.

Xiaoqin Ye, M.D., Ph.D.***
University of Georgia
Athens, Georgia

Research Associates

Melanie Ann Adams, Ph.D.

Fabio Agnelli, Ph.D.

Hanna-Stina Martinsson Ahlzén, Ph.D.

Reetesh Raj Akhouri, Ph.D.

Alexander Ivanov Alexandrov, Ph.D.

Stephen G. Aller, Ph.D.

Beatriz Gonzalez Alonso, Ph.D.

Juliano Alves, Ph.D.***
Genomics Institute of the Novartis Research Foundation
San Diego, California

Yu An, Ph.D.**
Millipore
Temecula, California

Brigitte Anliker, Ph.D.***
University of Düsseldorf
Düsseldorf, Germany

Andrew James Annalora, Ph.D.

Munehito Arai, Ph.D.

Roger Armen, Ph.D.Joseph W. Arndt, Ph.D.***
Biogen Idec
Cambridge, Massachusetts

Karunesh Arora, Ph.D.

Mabelle Ashe, Ph.D.^††††

Wojciech Augustyniak, Ph.D.

Jamie Mitchell Bacher, Ph.D.***
Rincon Pharmaceuticals
La Jolla, California

Sung-Hun Bae, Ph.D.

Manidipa Banerjee, Ph.D.

Konstantinos Beis, Ph.D.***
Imperial College London
London, England

Christine Beuck, Ph.D.

David Boehr, Ph.D.

Yannick Bomble, Ph.D.

David Bostick, Ph.D.

Giovanni Bottegoni, Ph.D.

Lintao Bu, Ph.D.

Tommy Bui, Ph.D.

Paul Card, Ph.D.^††††

Rosa Maria Cardoso, Ph.D.

Justin E. Carlson, Ph.D.^††††

Andrew Barry Carmel, Ph.D.

Qing Chai, M.D., Ph.D.***
Applied Molecular Evolution
San Diego, California

Ramya Thirumalai Chakravarthy, Ph.D.

Amarnath Chatterjee, Ph.D.

Susana Chaves, Ph.D.Jianhan Chen, Ph.D.***
Kansas State University
Manhattan, Kansas

Weihsu Claire Chen, Ph.D.

Yen-Ju Chen, Ph.D.

Ying Chen, M.D.

Zhiyong Chen, Ph.D.***
Trius Therapeutics, Inc.
San Deigo, California

Srinivas Chittaboina, Ph.D.

Jungwoo Choe, Ph.D.***
University of Seoul
Seoul, Korea

Ji Woong Choi, Ph.D.

Chung Jen Chou, Ph.D.

Li-Chiou Chuang, Ph.D.

Linda Maria Columbus, Ph.D.***
University of Virginia
Charlottesville, Virginia

Gladys Completo, Ph.D.

Stephen Connelly, Ph.D.

Adam Corper, Ph.D.

Sandro Cosconati, Ph.D.

Qizhi Cui, Ph.D.
National Research Council
Ottawa, Ontario, Canada

Carla P. Da Costa, Ph.D.^††††

Surya Kanta De, Ph.D.***
Burnham Institute for Medical Research
La Jolla, California

Robert de Bruin, Ph.D.

Paula Desplats, Ph.D.***
University of California
San Diego, California

Gerald Edward Dodson, Ph.D.

Claire Louise Dovey, Ph.D.

Zhanna Druzina, Ph.D.***
SGX Pharmaceuticals, Inc.
San Diego, California

Li-Lin Du, Ph.D.***
National Institute of Biological Sciences
Beijing, China

Michelle Duquette-Huber, Ph.D.

Scott Eberhardy, Ph.D.***
Schering-Plough Corporation
Union, New Jersey

Stephen Edgcomb, Ph.D.

Susanna V. Ekholm-Reed, Ph.D.

Daniel Felitsky, Ph.D.

Allan Chris Merrera Ferreon, Ph.D.

Josephine Chu Ferreon, Ph.D.

Yann Gambin, Ph.D.

Shannon E. Gardell, Ph.D.^††††

Charles Gersbach, Ph.D.

Joshua Gill, Ph.D.

Edith Caroline Glazer, Ph.D.

Rajib Kumar Goswami, Ph.D.

Bettina Groschel, Ph.D.

Hai-Ming Guo, Ph.D.

Min Guo, Ph.D.

Mahender Gurram, Ph.D.

Bong Kwan Han, Ph.D.***
Cornell University
Ithaca, New York

Byung Woo Han, Ph.D.

Shoufa Han, Ph.D.***
Xiamen University
Xiamen, China

Rodney Harris, Ph.D.

David M. Herman, Ph.D.

Deron Herr, Ph.D.

Joreg Hinnerwisch, Ph.D.***
ALTANA Chemie AG
Wesel, Germany

Kenichi Hitomi, Ph.D.

Minsun Hong, Ph.D.

Wen-Xu Hong, Ph.D.

Yunfeng Hu, Ph.D.***
Tanabe Research Laboratories U.S.A., Inc.
San Diego, California

Zheng-Zheng Huang, Ph.D.

Kwan Hoon Hyun, Ph.D.***
CrystalGenomics
Seoul, Korea

Masanori Imai, Ph.D.***
Hokkaido Pharmaceutical University
Hokkaido, Japan

Veli-Pekka Jaakola, Ph.D.

Thamara Janaratne, Ph.D.

Kai Jenssen, Ph.D.***
Merz Pharma
Frankfurt, Germany

Margaret Alice Johnson, Ph.D.

Steven Johnson, Ph.D.

Susanna Juraja, Ph.D.

Christian Kannemeier, Ph.D.***
PrimeCell Therapeutics L.L.C.
Irvine, California

Mili Kapoor, Ph.D.Andrey Aleksandrovich Karyakin, Ph.D.

Yang Khandogin, Ph.D.***
University of Oklahoma
Norman, Oklahoma

Ilja V. Khavrutskii, Ph.D.***
University of California
San Diego, California

Reza Khayat, Ph.D.

Dae Hee Kim, Ph.D.

Jennifer Knight, Ph.D.

Eda Koculi, Ph.D.

Bethany Koehntop, Ph.D.

Milka Kostic, Ph.D.***
Cell Press
Cambridge, Massachussetts

Irina Kufareva, Ph.D.

Shantanu Kumar, Ph.D.*** University of California
San Diego, California

Sharon Kwan, Ph.D.

Bianca Lam, Ph.D.

Emma Langley, Ph.D.

Jason Lanman, Ph.D.

Chang-Wook Lee, Ph.D.

Chul Won Lee, Ph.D.

June Hyung Lee, Ph.D.***
New York University
New York, New York

Sophie Lefebvre, Ph.D.

Edward Lemke, Ph.D.

Liao Liang, Ph.D.

Vasco Liberal, Ph.D.

William M. Lindstrom, Ph.D.

Bin Liu, Ph.D.Kunheng Luo, Ph.D.

Ann MacLaren, Ph.D.***
Biogen Idec
San Diego, California

Darly Joseph Manayani, Ph.D.

Jeff Mandell, Ph.D.***
Ionian Technologies, Inc.
San Diego, California

Santiago Cavero Martinez, Ph.D.

Tsutomu Matsui, Ph.D.

Derrick Meinhold, Ph.D.

Eva Mejia Ramirez De Arellano, Ph.D.

Elena Menichelli, Ph.D.

Jonathan Mikolosko, Ph.D.

Mauro Mileni, Ph.D.

Maki Minakawa, Ph.D.

Marissa Mock, Ph.D.***
Biocatalytics
Pasadena, California

Biswaranjan Mohanty, Ph.D.

Samrat Mukhopadhyay, Ph.D.

Tetsuji Mutoh, Ph.D.

Sujatha Narayan, Ph.D.^††††

Mir Hussain Nawaz, Ph.D.

Hung Nguyen, Ph.D.

Tuan Nguyen, Ph.D.

George Nicola, Ph.D.

Tadateru Nishikawa, Ph.D.***
Bruker BioSpin
Tsukuba, Japan

Kyoko Noguchi, M.D., Ph.D.

Wataru Nomura, Ph.D.***
Tokyo Medical and Dental University
Tokyo, Japan

Amy Odegard, Ph.D.

Lisa Renee Olano, Ph.D.

Brian L. Olson, Ph.D.***
St. Cloud University
St. Cloud, Minnesota

Akira Onoda, Ph.D.

Mary O'Reilly, Ph.D.

Brian Paegel, Ph.D.

Sung-Jean Park, Ph.D.

Sandeep Patel, Ph.D.***
University of Delaware
Newark, Delaware

Stephanie Pebernard, Ph.D.

Bill Francesco Pedrini, Ph.D.

Robert Pejchal, Ph.D.

Vladimir Pelmenschikov, Ph.D.

Jefferson Perry, Ph.D.

Suzanne Peterson, Ph.D.

Jessica Petrillo, Ph.D.

Goran Pljevaljùci«c, Ph.D.

Stephanie Pond, Ph.D.

John Prudden, Ph.D.

Christopher L. Reyes, Ph.D.***
Biogen Idec
San Diego, California

Kimberly A. Reynolds, Ph.D.

Jin-Kyu Rhee, Ph.D.

Gabriela Ring, Ph.D.

Riturparna Sinha Roy, Ph.D.

Sanjay Adrian Saldanha, Ph.D.***
Translational Research Institute, Scripps Florida

Mariana Santa-Marta, Ph.D.

Andre Schiefner, Ph.D.

Lauren J. Schwimmer, Ph.D.

Jennifer S. Scorah, Ph.D.

Alim Seit-Nebi, Ph.D.

Pedro Serrano-Navarro, Ph.D.

Craig McLean Shepherd, Ph.D.***
Burnham Institute for Medical Research
La Jolla, California

David S. Shin, Ph.D.

Develeena Shivakumar, Ph.D.***
University of Chicago
Chicago, Illinois

David A. Shore, Ph.D.

Daniela Andrea Slavin, Ph.D.

Elisabetta Soragni, Ph.D.

Surya Venkata Sripada, Ph.D.

Pawel Stanczak, Ph.D.

Thomas Steinbrecher, Ph.D.

Shih-Che Su, Ph.D.

Sebastian Sudek, Ph.D.

Magnus Sundstrom, Ph.D.

Michael T. Sykes, Ph.D.

Blair R. Szymczyna, Ph.D.

Hiroaki Tateno, Ph.D.***
National Institute of Advanced Industrial Sceince and Technology
Tsukuba, Japan

Rebecca E. Taurog, Ph.D.

Ewan Richardson Taylor, Ph.D.

Leonardo Teixeira, Ph.D.

Hua Tian, Ph.D.

Mauricio Carrillo Tripp, Ph.D.

Oleg Trott, Ph.D

Ulrich Tschulena, Ph.D.***
German Cancer Research Center
Heidelberg, Germany

Julie L. Tubbs, Ph.D.

Sorin Tunaru, Ph.D.

Naoto Utsumi, Ph.D.

Frank van Drogen, Ph.D.***
Institute für Biochemie
Zürich, Switzerland

Ajay Vashisht, Ph.D.

Sangita Venkataraman, Ph.D.

Petra Verdino, Ph.D.

My Vo, Ph.D.

William Frederick Waas, Ph.D.***
Defined Health
Florham Park, New Jersey

Shun-ichi Wada, Ph.D.^††††

Jun Wang, Ph.D.

Jessica Williams, Ph.D.

Robert Scott Williams, Ph.D.

Eric L. Wise, Ph.D.***
Wayne State University
Detroit, Michigan

Jonathan Wojciak, Ph.D.***
Lpath, Inc.
San Diego, California

Vance Wong, Ph.D.

Timothy I. Wood, Ph.D.***
Walter Reed Army Medical Center
Washington, D.C.

Wei Xie, Ph.D.

Lan Xu, Ph.D.***
BioVerdant
San Diego, California

Yoshiki Yamada, Ph.D.

Tohru Yamagaki, Ph.D.

Atsushi Yamagata, Ph.D.***
Tokyo University
Tokyo, Japan

Yongjun Ye, Ph.D.***
VIRxSYS Corporation
Gaithersburg, Maryland

Kye Sook Yi, Ph.D.

Yong Yin, Ph.D.^††††

Sung-Il Yoon, Ph.D.

Kenji Yoshimoto, Ph.D.

Naoto Yoshizuka, M.D., Ph.D.

Yuan Yuan, Ph.D.***
Millipore
Temecula, California

Markus Zeeb, Ph.D.***
Boehringer Ingelheim GmbH
Biberach an der Riss, Germany

Ying Zeng, Ph.D.

Haile Zhang, Ph.D.

Qing Zhang, Ph.D.

Wei Zhang, Ph.D.

Yong Zhao, Ph.D.

Scientific Associates

Enrique Abola, Ph.D.

Andrew S. Arvai, M.S.Ognian V. Bohorov, Ph.D.

Dennis Carlton, B.S.

Vadim Cherezov, Ph.D.

Ellen Yu-Lin Tsai Chien, Ph.D.

Xiaoping Dai, Ph.D.

Marc Deller, D.Phil

Gye Won Han, Ph.D.

Wenge Han, Ph.D.

Michael Allen Hanson, Ph.D.

Hope Johnson, Ph.D.

Marcy A. Kingsbury, Ph.D.***
Indiana University
Bloomington, Indiana

Padmaja Natarajan, Ph.D.^††††

Lin Wang, Ph.D.

Visiting Investigators

Stephen J. Benkovic, Ph.D.
Pennsylvania State University
University Park, Pennsylvania

Wayne A. Fenton, Ph.D.
Yale University
New Haven, Connecticut

Astrid Graslund, Ph.D.
Stockholm University
Stockholm, Sweden

Arne Holmgren, M.D., Ph.D.
Karolinska Institutet
Stockholm, Sweden

Barry Honig, Ph.D.
Columbia University
New York, New York

Arthur Horwich, M.D.
Yale University
New Haven, Connecticut

Tai-Huang Huang, Ph.D.
Academica Sinica
Taipei, Taiwan

Joseph David Ng, Ph.D.
University of Alabama
Huntsville, Alabama

Victoria A. Roberts, Ph.D.
University of California
San Diego, California

Robert D. Rosenstein, Ph.D.
Lawrence Berkeley National Laboratory
Berkeley, California

Debbie Tahmassebi, Ph.D.
University of San Diego
San Diego, California

* Joint appointment in The Skaggs Institute for Chemical Biology
** Joint appointments in the Department of Chemistry and The Skaggs Institute for Chemical Biology
*** Appointment completed; new location shown
**** Joint appointment in the Department of Molecular and Integrative Neurosciences
***** Joint appointments in the Department of Immunology and The Skaggs Institute for Chemical Biology
^†Joint appointment in the Department of Cell Biology
^††Joint appointment in the Department of Molecular and Experimental Medicine
^†††Joint appointment in the Department of Chemistry
^†††† Appointment completed