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Scientific Report 2006


The Skaggs Institute for Chemical Biology




Director's Overview

Staff

Julius Rebek, Jr., Ph.D.*
Professor and Director

Carlos F. Barbas III, Ph.D.**
Professor
Janet and W. Keith Kellogg II Chair in Molecular Biology

Tamas Bartfai, Ph.D.
Professor
Chairman, Molecular and Integrative Neurosciences Department, Scripps Research
Director, Harold L. Dorris Neurological Research Institute

Ernest Beutler, M.D.***
Professor
Chairman, Department of Molecular and Experimental Medicine, Scripps Research

Dale L. Boger, Ph.D.*
Richard and Alice Cramer Professor of Chemistry

Geoffrey Chang, Ph.D.**
Associate Professor

Benjamin F. Cravatt, Ph.D.****
Professor
Director, Helen L. Dorris Child & Adolescent Neuro-Psychiatric Disorder Institute

Philip Dawson, Ph.D.*****
Associate Professor

Gerald M. Edelman, M.D., Ph.D.
Professor
Chairman, Department of Neurobiology, Scripps Research

Albert Eschenmoser, Ph.D.*
Professor

Martha J. Fedor, Ph.D.**
Associate Professor

M.G. Finn, Ph.D.*
Associate Professor

Elizabeth D. Getzoff, Ph.D.††
Professor

M. Reza Ghadiri, Ph.D.*
Professor

Kim D. Janda, Ph.D.*
Professor
Ely R. Callaway, Jr., Chair in Chemistry
Director, The Worm Institute for Research and Medicine

Gerald F. Joyce, M.D., Ph.D.†††
Professor
Dean, Faculty

Ehud Keinan, Ph.D.**
Adjunct Professor

Jeffery W. Kelly, Ph.D.*
Lita Annenberg Hazen Professor of Chemistry
Dean, Graduate and Postgraduate Studies

Richard A. Lerner, M.D.†††
President, Scripps Research
Lita Annenberg Hazen Professor of Immunochemistry
Cecil H. and Ida M. Green Chair in Chemistry

Stephen P. Mayfield, Ph.D.*****
Professor
Associate Dean, Kellogg School of Science and Technology

K.C. Nicolaou, Ph.D.*
Aline W. and L.S. Skaggs Professor of Chemical Biology
Darlene Shiley Chair in Chemistry
Chairman, Department of Chemistry, Scripps Research

Paul R. Schimmel, Ph.D.†††
Ernest and Jean Hahn Professor and Chair in Molecular Biology and Chemistry

Peter Schultz, Ph.D.*
Professor
Scripps Family Chair

K. Barry Sharpless, Ph.D.*
W.M. Keck Professor of Chemistry

Subhash C. Sinha, Ph.D.**
Associate Professor

John A. Tainer, Ph.D.**
Professor

James R. Williamson, Ph.D.†††
Professor
Associate Dean, Kellogg School of Science and Technology

Ian A. Wilson, D.Phil.**
Professor

Chi-Huey Wong, Ph.D.*
Ernest W. Hahn Professor and Chair in Chemistry

Peter E. Wright, Ph.D.**
Professor
Cecil H. and Ida M. Green Investigator in Biomedical Research
Chairman, Department of Molecular Biology, Scripps Research

Kurt Wüthrich, Ph.D.†††
Cecil H. and Ida M. Green Professor of Structural Biology



Research Associates††††

Dariush Ajami, Ph.D.

Elizabeth Barrett, Ph.D.

Sara Butterfield, Ph.D.

Alexandre Carella, Ph.D.

Naran Gombosuren, Ph.D.

Clemens Haas, Ph.D.

Junli Hou, Ph.D.

Richard J. Hooley, Ph.D.

Tetsuo Iwasawa, Ph.D.

Enrique Mann, Ph.D.

Lionel Moisan, Ph.D.

Andrew Myles, Ph.D.

Severin Odermatt, Ph.D.

Riccardo Salvio, Ph.D.

Michael Schramm, Ph.D.

Siddhartha Shenoy, Ph.D.

Alessandro Volonterio, Ph.D.

Felix Zelder, Ph.D.

* Joint appointment in the Department of Chemistry
** Joint appointment in the Department of Molecular Biology
*** Joint appointment in the Department of Molecular and Experimental Medicine
**** Joint appointments in the Departments of Cell Biology and Chemistry
***** Joint appointment in the Department of Cell Biology
Joint appointment in the Department of Neurobiology
†† Joint appointments in the Departments of Molecular Biology and Immunology
††† Joint appointments in the Departments of Chemistry and Molecular Biology
†††† Research associates in the laboratories of staff other than Dr. Rebek are included in the lists of the respective departments in which the associates hold joint appointments.

 


Wide-angle perspective: Looking down the barrel of the cylindrical capsule, we find n-tetradecane
in a coiled, helical conformation. At first glance, this imposition of host on guest appears unfavorable, but in the end, adaptation maximizes
contact between the two and results in an induced-fit match. Work for the image done by Michael P. Schramm, Ph.D., The Skaggs Institute for Chemical Biology.