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Scientific Report 2006


Immunology





Chairman's Overview

Staff


Richard J. Ulevitch, Ph.D.
Professor and Chairman

Bruce A. Beutler, M.D.
Professor

Roberto Baccala, Ph.D.
Assistant Professor

Gary M. Bokoch, Ph.D.*
Professor

Dennis R. Burton, Ph.D.**
Professor

Tsung-Hsien Chuang, Ph.D.
Assistant Professor

Charles G. Cochrane, M.D.
Professor Emeritus

Neil R. Cooper, M.D.
Professor Emeritus

Linda K. Curtiss, Ph.D.
Professor

Edward A. Dennis, Ph.D.
Adjunct Professor

Henrik Ditzel, M.D., Ph.D.
Adjunct Professor

Frank J. Dixon, M.D.
Professor Emeritus
Director Emeritus, Scripps Research

Thomas S. Edgington, M.D.
Professor

Ann J. Feeney, Ph.D.
Associate Professor

Philippe Gallay, Ph.D.
Associate Professor

Nicholas R.J. Gascoigne, Ph.D.
Professor

Amanda Gavin, Ph.D.
Assistant Professor

Peter Ghazal, Ph.D.
Adjunct Associate Professor

Jiahuai Han, Ph.D.
Professor

Wendy L. Havran, Ph.D.
Professor

Shuang Huang, Ph.D.
Assistant Professor

Julie Jameson, Ph.D.
Assistant Professor

Jonathan G. Kaye, Ph.D.
Associate Professor

Richard Klemke, Ph.D.***
Associate Professor
Moores Cancer Center
San Diego, California

Norman R. Klinman, M.D., Ph.D.
Professor

Ulla Gissi Knaus, Ph.D.
Associate Professor

Dwight Kono, M.D.
Associate Professor

Jiing-Dwan Lee, Ph.D.
Associate Professor

Erguang Li, Ph.D.
Assistant Professor

Cheng Liu, M.D., Ph.D.
Assistant Professor

Nigel Mackman, Ph.D.
Associate Professor

Michael McHeyzer-Williams, Ph.D.
Associate Professor

Dianne McKay, M.D.
Assistant Professor

Donald E. Mosier, M.D., Ph.D.
Professor

Kerri A. Mowen, Ph.D.
Assistant Professor

David Nemazee, Ph.D.
Professor

Glen R. Nemerow, Ph.D.
Professor

Per A. Peterson, M.D., Ph.D.
Adjunct Professor

Pascal Poignard, M.D.
Adjunct Assistant Professor

Ralph A. Reisfeld, Ph.D.
Professor

Matthias Riewald, M.D.
Assistant Professor

Hugh Rosen, M.D., Ph.D.
Professor

Wolfram Ruf, M.D.
Professor

Daniel R. Salomon, M.D.
Adjunct Associate Professor

Erica Ollmann Saphire, Ph.D.
Assistant Professor

Nora Sarvetnick, Ph.D.
Professor

David Schlaepfer, Ph.D.
Associate Professor

Linda A. Sherman, Ph.D.
Professor

Jonathan Sprent, M.D., Ph.D.
Adjunct Professor

Charles D. Surh, Ph.D.
Associate Professor

Luc Teyton, M.D., Ph.D.
Associate Professor

Argyrios N. Theofilopoulos, M.D.
Professor

Peter S. Tobias, Ph.D.
Associate Professor

Susan R. Webb, Ph.D.
Associate Professor

R. Anthony Williamson,
Associate Professor

Curtis B. Wilson, M.D.
Professor Emeritus

Rong Xiang, M.D., Ph.D.
Assistant Professor

Michael Zwick, Ph.D.
Assistant Professor
 

Staff Scientists


Steven Brown, Ph.D.

Udayan Chatterji, Ph.D.

Xin Du, Ph.D.

Colleen Fearns, Ph.D.

Vladimir Kravchenko, Ph.D.

John Mathison, Ph.D.

Anil Munshi, Ph.D.

Rafal Pawlinski, Ph.D.

Ramona Petrovan, Ph.D.

M. Germana Sanna, Ph.D.

Laura Solforosi, Ph.D.

Deborah Witherden, Ph.D.


Senior Research Associates


Jasimuddin Ahamed, Ph.D.

Gourab Bhattarcharjee, Ph.D.

Joao da Silva Correia, Ph.D.

Amr Abdelhamid El Sheikh, Ph.D

Kasper Hoebe, Ph.D.

Eujing Jo, Ph.D.

Hyun-ku Lee, Ph.D.

Rui Lin, Ph.D.

Qilin Pan, Ph.D.

Andrew Saphire, Ph.D.

Yan Wu, Ph.D.****


Research Associates


Djemel Ait-Azzouzene, Ph.D.

Christopher Alfonso, Ph.D.***
BD PharMingen
San Diego, California

Sandrine Arnaud-Dabernat, Ph.D.

Caroline Aylott, Ph.D.****

Ann Bellon, Ph.D.

Michael Berger, Ph.D.

Dafang Bian, Ph.D.****

Joerge Birkenfeld, Ph.D.

Onur Boyman, Ph.D.***
Centre Hospitalier Universitaire Vaudois
Immunology and Allergology
Lausanne, Switzerland

Carlos Cantu, Ph.D.***
Digital Gene Technologies
La Jolla, California

John B. Carey, Ph.D.

Jianming Chen, Ph.D.

Marie Cherrier, Ph.D.

Roshni Chintalapati, Ph.D.

Jae Ho Cho, Ph.D.****

David Chodniewicz, Ph.D.****

Ben Croker, Ph.D.

Aimee de Catherlineu, Ph.D.

Shrimati Datta, Ph.D.
Eleuterio De La Camara, Ph.D. ***
Centro Nacional de Investigaciones Cardiovasculares
Madrid, Spain

Violane Delorme, Ph.D.

Celine Der Mardirossian, Ph.D.

Benoit Besnues, Ph.D.

Anthony Don, Ph.D.

Helen Donners, Ph.D.***
Institute of Tropical Medicine
Antwerp, Belgium

Celine Eidenschenk, Ph.D.

Celia Espinoza, Ph.D.****

Nicolas Fazilleau, Ph.D.

Clemens Feistritzer, M.D.

Christofer Flood, Ph.D.

Linda Frederick, Ph.D.***
Favrille, Inc.
San Diego, California

Stefan Freigang, Ph.D.

Guo Fu, Ph.D.

Michelle Fung, Ph.D.

Philippe Georgel, Ph.D.***
Laboratoire d’Immunogénétique Moléculaire Humaine
Strasbourg, France

Davide Gianni, Ph.D.

Cristina Gil-Lamaignere, Ph.D.***
Department of Cell Biology
Scripps Research

Pedro Gonzalez-Cabrera, Ph.D.

Fang Guo, Ph.D.Emma Hamilton-Williams, Ph.D.

Lars Hangartner, Ph.D.

Masaaki Hayashi, M.D., Ph.D.

Natasha Hill, Ph.D.

Neil John Hime, Ph.D.

Shihe Hou, Ph.D.***
Abraxis BioScience Inc.
Los Angeles, California

Hong Hua, Ph.D.

Timothy Huang, Ph.D.

Christoph Huber, Ph.D.

Milena Iacobelli, Ph.D.

Hassan Issafras, Ph.D.

Zhengfan Jiang, Ph.D.

Wong Soon Justin, Ph.D.

Young Jun Kang, Ph.D.

Yu-Ya Kao, Ph.D.

Charles Kaplan, Ph.D.***
Genentech Corporation
San Francisco, California

Linda Kidd, Ph.D.

Chang-Hoon Kim, Ph.D.

Hee Ok Kim, Ph.D.****

Jun-Sub Kim, Ph.D.

Sungwoo Kim, Ph.D.***
Assistant Professor
University of Calgary
Calgary, Alberta, Canada

Rachel Kohler, Ph.D.

Edguardo Kolkowski, Ph. D.

Marek Kovar, Ph.D.****

Jirina Kovarova, Ph.D.****

Carsten Kreig, Ph.D.

Joerge Krueger, M.D.***
Charité Children’s Hospital
Berlin, Germany

Toru Kurokawa, Ph.D.

Yumi Kurokawa, Ph.D.

Young Back Kwon, Ph.D.****

Cheng Yu Lai, Ph.D.

Jennifer Lamoureux, Ph.D.

Elise Landais, Ph.D.

Mansun Law, Ph.D.

Jeff Lee, Ph.D.

Sang-Un Lee, Ph.D.***
Cummings School of Veterinary Medicine at Tufts University
North Grafton, Massachusetts

Sung-Hyung Lee, Ph.D.***
Baylor College of Medicine
Houston, Texas

Cheng Li, Ph.D.****

Jiali Li, Ph.D.

Xiang Li, Ph.D.

Yang Mi Li, Ph.D.

Yilei Li, Ph.D.***
South China Medical University
Guangzhou, China

Ssang-Taek Lim, Ph.D.

Yang Mi Lim, Ph.D.

Ting-Kun Lin, M.D., Ph.D.***
Kaiser Permanente Medical Center
San Francisco, California

Guoxun Liu, Ph.D.****

Yuan Liu, Ph.D.

Carina Lotz, Ph.D.***
Netherlands Cancer Institute
Amsterdam, the Netherlands

Christine Louis dit Sully, Ph.D.

Yunping Luo, M.D., Ph.D.

James P. Luyendyk, Ph.D.

Michael Lyman, Ph.D.

Chitladda Mahanivong, Ph.D.

Laurent Malherbe, Ph.D.

Maria Manukyan, Ph.D.

Annette Marleau, Ph.D.

Beatriz Maroto, Ph.D.***
Centro Nacional de Investigaciones Oncológicas
Madrid, Spain

David Marsolais, Ph.D.

Javier Martinez, Ph.D.

Terrence Meehan, Ph.D.

Satyajit Mitra, Ph.D.

Johann Mols, Ph.D.

Adam Mullick, Ph.D.

Perihan Nalbant, Ph.D.

Ron Nepomuceno, Ph.D.

Frank Karl Niessen, Ph.D.

Miyo Ota, Ph.D.

Takayuki Ota, Ph.D.

Motoyuki Otsuka, Ph.D.

Sandrine Pacquelet, Ph.D.

Nadige Pelletier, Ph.D.

Olivier Pertz, Ph.D.***
University of California
San Diego, California

Helle Petersen, Ph.D.

Jared Purton, Ph.D.

Christopher Ramsey, Ph.D.

M. Rachel Richards, Ph.D.

Elise Romeo, Ph.D.

Mark Rubenstein, Ph.D.***
University of California
San Diego, California

Monica Ruse, Ph.D.

Sophie Rutschmann, Ph.D.

Janelle Salkowitz-Bokal, Ph.D.

Prabhakar Salunkhe, Ph.D.***
Burnham Institute
La Jolla, California

Jorge Luis Schettini, Ph.D.

Nicolas Schrantz, Ph.D.

Reto Andreas Schupbach, Ph.D.

Alim Seit-Nebi, Ph.D. ***
Department of Molecular Biology
Scripps Research

Suganya Selvarajah, Ph.D.

Shigeki Shimada, Ph.D.

Jason Smith, Ph.D.

Michelle Solomon, Ph.D.****

Gabriel Sternik, Ph.D.

Konstantin Stoletov, Ph.D.***
Moores Cancer Center
San Diego, California

Joyce Tan, Ph.D.***
Anadys Pharmceuticals
San Diego, California

Rachel Tilley, Ph.D.

Antoine Toulon, Ph.D.

Joie Trifilo, Ph.D.****

Marina Tsatmali, Ph.D.

David Valenta, Ph.D.

Sebastian Vallee, Ph.D.

Ester Van Leeuwen, Ph.D.

Laurent Verkoczy, Ph.D.***
Duke University
Durham, North Carolina

Hendrik Versteeg, Ph.D.

Nicole Von Allmen-Zurcher, Ph.D.

Katharina Von Lohneysen, Ph.D.

Meng Wang, M.D.

Yingchun Wang, Ph.D.***
Moores Cancer Center
San Diego, California

Zhao Wang, Ph.D.

Megumi Watanabe, Ph.D.

Chenghong Wei, Ph.D.

Christopher Wiethoff, Ph.D.***
Loyola University
Chicago, Illinois

Justin Soon Boon Wong, Ph.D.

Chia Cheng Wu, Ph.D.

Wenyuan Wu, Ph.D.

Chengran Xu, Ph.D.

Yue Xu, Ph.D.

Pia Yachi, Ph.D.

Deepak Yadav, Ph.D.

Michael Ye, Ph.D.

Sook Wah Yee, Ph.D.

Sun-Hee Yoon, Ph.D.****

Kenji Yoshida, Ph.D.

Jiangiang Yu, Ph.D.

Hui Zhang, Ph.D.

You Qing Zhang, Ph.D.

Tieming Zhao, Ph.D.

He Zhou, Ph.D.

Huamin Zhou, Ph.D.***
Xiamen University
Xiamen, China


Scientific Associates


Rosana Gonzales-Quintal, Ph.D.

Marcie Rose Kritzik, Ph.D.

Nora Leaf

Ralph Pantophlet, Ph.D.

Dongyuan Xia, Ph.D.

* Joint appointment in the Department of Cell Biology
** Joint appointment in the Department of Molecular Biology
*** Appointment completed, new location shown
**** Appointment complete

 


Nascent Drosophila Toll-8 crystals. Toll receptors are critical signaling receptors of development and of innate immunity conserved in evolution from flies to humans. Recombinant forms of these receptors are used to grow crystals and determine structures in order to establish a structure-function relationship. Work done in the laboratory of Luc Teyton, M.D., Ph.D.