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Scientific Report 2005


Immunology





Chairman's Overview

Staff


Richard J. Ulevitch, Ph.D.
Professor and Chairman

Roberto Baccala, Ph.D.
Assistant Professor

Bruce A. Beutler, M.D.
Professor

Gary M. Bokoch, Ph.D.*
Professor

Dennis R. Burton, Ph.D.**
Professor

David A. Cheresh, Ph.D.***
Professor
Moores Cancer Center
La Jolla, California

Robert W. Chesnut, Ph.D.
Adjunct Associate Professor

Tsung-Hsien Chuang, Ph.D.
Assistant Professor

Charles G. Cochrane, M.D.
Professor Emeritus

Neil R. Cooper, M.D.
Professor Emeritus

Linda K. Curtiss, Ph.D.
Professor

Edward A. Dennis, Ph.D.
Adjunct Professor

Henrik Ditzel, M.D., Ph.D.
Adjunct Professor

Frank J. Dixon, M.D.
Professor Emeritus
Director Emeritus, Scripps Research

Thomas S. Edgington, M.D.
Professor

Colleen Fearns, Ph.D.
Assistant Professor

Ann J. Feeney, Ph.D.
Associate Professor

Philippe Gallay, Ph.D.
Associate Professor

Nicholas R.J. Gascoigne, Ph.D.
Professor

Peter Ghazal, Ph.D.
Adjunct Associate Professor

Howard Gray, Ph.D.
Adjunct Professor

Jiahuai Han, Ph.D.
Professor

Wendy L. Havran, Ph.D.
Associate Professor

Shuang Huang, Ph.D.
Assistant Professor

Jonathan G. Kaye, Ph.D.
Associate Professor

Hidehiro Kishimoto, M.D., Ph.D.***
Associate Professor
Tokyo University of Science
Tokyo, Japan

Richard Klemke, Ph.D.
Associate Professor

Norman R. Klinman, M.D., Ph.D.
Professor

Ulla Gissi Knaus, Ph.D.
Associate Professor

Dwight Kono, M.D.
Associate Professor

Vladimir V. Kravchenko, Ph.D.
Assistant Professor

Jiing-Dwan Lee, Ph.D.
Associate Professor

Erguang Li, Ph.D.
Assistant Professor

Cheng Liu, M.D., Ph.D.
Assistant Professor

Nigel Mackman, Ph.D.
Associate Professor

Michael McHeyzer-Williams, Ph.D.
Associate Professor

Dianne McKay, M.D.
Assistant Professor

Donald E. Mosier, M.D., Ph.D.
Professor

Kerri A. Mowen, Ph.D.
Assistant Professor

David Nemazee, Ph.D.
Professor

Glen R. Nemerow, Ph.D.
Associate Professor

Per A. Peterson, M.D., Ph.D.
Adjunct Professor

Mary Laurie Phillips, Ph.D.
Adjunct Assistant Professor

Pascal Poignard, M.D.
Adjunct Assistant Professor

Ralph A. Reisfeld, Ph.D.
Professor

Matthias Riewald, M.D.
Assistant Professor

Hugh Rosen, M.D., Ph.D.
Professor

Wolfram Ruf, M.D.
Associate Professor

Daniel R. Salomon, M.D.
Adjunct Associate Professor

Erica Ollmann Saphire, Ph.D.
Assistant Professor

Nora Sarvetnick, Ph.D.
Professor

David Schlaepfer, Ph.D.
Associate Professor

Allesandro Sette, Ph.D.
Adjunct Assistant Professor

Linda A. Sherman, Ph.D.
Professor

Jonathan Sprent, M.D., Ph.D.
Professor

Charles D. Surh, Ph.D.
Associate Professor

Luc Teyton, M.D., Ph.D.
Associate Professor

Argyrios N. Theofilopoulos, M.D.
Professor

Peter S. Tobias, Ph.D.
Associate Professor

Daniel Von Seggern, Ph.D.****
Assistant Professor

Susan R. Webb, Ph.D.
Associate Professor

R. Anthony Williamson, Ph.D.
Associate Professor

Curtis B. Wilson, M.D.
Professor Emeritus

Rong Xiang, M.D., Ph.D.
Assistant Professor

Michael Zwick, Ph.D.
Assistant Professor


Staff SCIENTISTS


Udayan Chatterji, Ph.D.

Xin Du, Ph.D.

John Mathison, Ph.D.

Anil Munshi, Ph.D.

Rafal Pawlinski, Ph.D.

M. Germana Sanna, Ph.D.

Deborah Witherden, Ph.D.


Senior Research Associates


Jasimuddin Ahamed, Ph.D.

Joao da Silva Correia, Ph.D.

Amr Abdelhamid El Sheikh, Ph.D.

Amanda Gavin, Ph.D.

Peter Goebel, Ph.D.***
IgE Therapeutics, Inc.
San Diego, California

Kasper Hoebe, Ph.D.

Julie Jameson, Ph.D.

Elisabeth Jeanclos, Ph.D.****

Cecile King, Ph.D.****

Liguo New, Ph.D.****

Qilin Pan, Ph.D.

Christine Pastore, Ph.D.****

Ramona Petrovan, Ph.D.

Andrew Saphire, Ph.D.

Dwayne Stupack, Ph.D.***
Moores Cancer Center
La Jolla, California

Sara Maree Weis, Ph.D.***
Moores Cancer Center
La Jolla, California

Yan Wu, Ph.D.

Tomasz Zal, Ph.D.***
M.D. Anderson Cancer Center
University of Texas
Houston, Texas


Research Associates


Djemel Ait-Azzouzene, Ph.D.

Seyed Alavizadeh, Ph.D.***
Moores Cancer Center
La Jolla, California

Christopher Alfonso, Ph.D.

Sandrine Arnaud-Dabernat, Ph.D.

Caroline Aylott, Ph.D.

Ann Bellon, Ph.D.

Gourab Bhattarcharjee, Ph.D.

Dafang Bian, Ph.D.

Joerge Birkenfeld, Ph.D.

Onur Boyman, Ph.D.

Carlos Cantu, Ph.D.

Sophie Chabot, Ph.D.****

Jianming Chen, Ph.D.

Zhong Chen, Ph.D ****

Marie Cherrier, Ph.D.Roshni Chintalapati, Ph.D.

Jae Ho Cho, Ph.D.

David Chodniewicz, Ph.D.

Ben Croker, Ph.D.

Jianhua Cui, Ph.D.***
Moores Cancer Center
La Jolla, California

Aimee de Catherlineu, Ph.D.

Eleuterio De La Camara, Ph.D.

Violane Delorme, Ph.D.

Celine Der Mardirossian, Ph.D.

Becky Diebold, Ph.D.***
Emory University
Atlanta, Georgia

Anthony Don, Ph.D.

Helen Donners, Ph.D.

Stefan Dunzendorfer, Ph.D.****

Mike Eisenbraun, Ph.D.****

Celia Espinoza, Ph.D.

Nicolas Fazilleau, Ph.D.

Clemens Feistritzer, M.D.

Christofer Flood, Ph.D.

Linda Frederick, Ph.D.

Stefan Freigang, Ph.D.

Guo Fu, Ph.D.

Philippe Georgel, Ph.D.

Cristina Gil-Lamaignere, Ph.D.

Jonathan Gitlin, Ph.D.***
University of Kentucky
Lexington, Kentucky

Antje Gohla, Ph.D.****

Emma Hamilton-Williams, Ph.D.

Masaaki Hayashi, M.D., Ph.D.

Natasha Hill, Ph.D.Neil John Hime, Ph.D.

Shihe Hou, Ph.D.

Hong Hua, Ph.D.

Timothy Huang, Ph.D.

Christoph Huber, Ph.D.

Milena Iacobelli, Ph.D.

Naaozumi Ishimaru, Ph.D.***
University of Tokushima
Tokushima, Japan

Hassan Issafras, Ph.D.

Zhengfan Jiang, Ph.D.

Hyun-Bae Jie, Ph.D.***
Harvard University
Cambridge, Massachusetts

Euijung Jo, Ph.D.

Valeria Judkowski, Ph.D.****

Wong Soon Justin, Ph.D.

Young Jun Kang, Ph.D.

Yu-Ya Kao, Ph.D.

Charles Kaplan, Ph.D.

Ayse Kayali, Ph.D.Hee Ok Kim, Ph.D.

Sungwoo Kim, Ph.D.

Rachel Kohler, Ph.D.

Elizabeth Kompfner, Ph.D.****

Veera Reddy Konda, Ph.D.***
Metagenics Inc.
Gig Harbor, Washington

Marek Kovar, Ph.D.

Jirina Kovarova, Ph.D.

Carsten Kreig, Ph.D.

Joerge Krueger, M.D.

Toru Kurakawa, Ph.D.

Yumi Kurokawa, Ph.D.

Sabine Kurz, Ph.D.***
Invitrogen Co.
Carlsbad, California

Young Back Kwon, Ph.D.

Cheng Yu Lai, Ph.D.

Jennifer Lamoureux, Ph.D.

Mansun Law, Ph.D.

Hyun-Ku Lee, Ph.D.Jeff Lee, Ph.D.

Sang-Un Lee, Ph.D.

Sung-Hyung Lee, Ph.D.

Young Kyung Lee, Ph.D.****

Cheng Li, Ph.D.

Hongbin Li, Ph.D.***
Harvard Medical School
Boston, Massachusetts

Jiali Li, Ph.D.

Xiang Li, Ph.D.

Yilei Li, Ph.D.

Ssang-Taek Lim, Ph.D.

Yang Mi Lim, Ph.D.

Rui Lin, Ph.D.

Ting-Kun Lin, M.D., Ph.D.

Jeffrey Lindquist, Ph.D.***
Moores Cancer Center
La Jolla, California

Guoxun Liu, Ph.D.

Yuan Liu, Ph.D.

Jeng-Fen Lo, Ph.D.****
Markus Loeffler, M.D.****

Carina Lotz, Ph.D.

Christine Louis dit Sully, Ph.D.

Yunping Luo, Ph.D.

Michael Lyman, Ph.D.

Chitladda Mahanivong, Ph.D.

Presanta Maiti, Ph.D.****

Laurent Malherbe, Ph.D.

Annette Marleau, Ph.D.

Beatriz Maroto, Ph.D.

Annica Martensson, Ph.D.****

Javier Martinez, Ph.D.

Terrence Meehan, Ph.D.

Satyajit Mitra, Ph.D.

Johann Mols, Ph.D.

Adam Mullick, Ph.D.

Eric Murphy, Ph.D.***
Moores Cancer Center
La Jolla, California

Perihan Nalbant, Ph.D.

Bishnu Nayak, Ph.D.****

Ron Nepomuceno, Ph.D.

Nathalie Niederberger, Ph.D.****

Frank Karl Niessen, Ph.D.

Motoyuki Otsuka, Ph.D.

Sandrine Pacquelet, Ph.D.

Oliver Pertz, Ph.D.

Helle Petersen, Ph.D.

Matthew Potter, Ph.D.***
Moores Cancer Center
La Jolla, California

Jared Purton, Ph.D.

Christopher Ramsey, Ph.D.

Jill Ricono, Ph.D.***
Moores Cancer Center
La Jolla, California

Mark Rubenstein, Ph.D.

Monica Ruse, Ph.D.

Sophie Rutschmann, Ph.D.

Prabhakar Salunkhe, Ph.D.

Yuichiro Sato, Ph.D.***
University of California San Diego Medical Center
San Diego, California

Gernot Schabbauer, Ph.D.****

Monica Schaller, Ph.D.***
Basel Hospital
Basel, Switzerland

Jorge Luis Schettini, Ph.D.

Nicolas Schrantz, Ph.D.

Alim Seit-Nebi, Ph.D.

Suganya Selvarajah, Ph.D.

Doinita Serban, Ph.D.***
Moores Cancer Center
La Jolla, California

Linda Sharp, Ph.D.****

Xuifei Shen, Ph.D.****

Fu Dong Shi, Ph.D.****

David Shields, Ph.D.***
Moores Cancer Center
La Jolla, California

Shigeki Shimada, Ph.D.

Jason Smith, Ph.D.

Laura Solforosi, Ph.D.

Michelle Solomon, Ph.D.

Gabriel Sternik, Ph.D.Konstantin Stoletov, Ph.D.

Shibing Su, Ph.D.****

Koichi Tabeta, Ph.D.****

Joyce Tan, Ph.D.

Rachel Tilley, Ph.D.

Joie Trifilo, Ph.D.

David Valenta, Ph.D.

Sebastian Vallee, Ph.D.

Laurent Verkoczy, Ph.D.

Hendrik Versteeg, Ph.D.

Katharina Von Lohneysen, Ph.D.

Meng Wang, M.D.

Yingchun Wang, Ph.D.

Zhao Wang, Ph.D.

Chenghong Wei, Ph.D.

Christopher Wiethoff, Ph.D.

Justin Soon Boon Wong, Ph.D.

Chia Cheng Wu, Ph.D.

Dong Wu, Ph.D.****

Wenyuan Wu, Ph.D.

Yue Xu, Ph.D.

Pia Yachi, Ph.D.

Deepak Yadav, Ph.D.

Jian Ming Yang, Ph.D.***
Department of Cell Biology, Scripps Research

Michael Ye, Ph.D.

Jinseong Yi, Ph.D.****

Sun-Hee Yoon, Ph.D.Kenji Yoshida, Ph.D.

Jiangiang Yu, Ph.D.

Hui Zhang, Ph.D.

You Qing Zhang, Ph.D.

Tieming Zhao, Ph.D.

He Zhou, Ph.D.

Huamin Zhou, Ph.D.

Zuping Zhou, Ph.D.****


Scientific Associates


Rosana Gonzales-Quintal, Ph.D.

Marcie Rose Kritzik, Ph.D.

Nora Leaf

Ralph Pantophlet, Ph.D.

Susan D. Revak****

Dongyuan Xia, Ph.D.

* Joint appointment in the Department of Cell Biology
** Joint appointment in the Department of Molecular Biology
*** Appointment completed; new location shown
**** Appointment completed

 


X-ray diffraction analyses of intact adenovirus. Top right panel, Adenovirus crystals. Top left panel, Schematic diagram of adenovirus particles and the location of protein subunits. Middle panel, Diffraction pattern obtained at a synchrotron beamline. Bottom left panel, Unit cell dimensions and space group of adenovirus particles in the crystals. The work represents a collaboration between the laboratories of Glen R. Nemerow, Ph.D., Department of Immunology, and Vijay Reddy, Ph.D., Department of Molecular Biology.