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The Skaggs Institute For Chemical Biology
Scientific Report 1998-1999



President's Introduction

Director's Overview


Staff

Julius Rebek, Jr., Ph.D.* Director and Professor
Carlos F. Barbas III, Ph.D.** Associate Professor, Janet and W. Keith Kellogg II Chair in Molecular Biology
Ernest Beutler, M.D.*** Professor
Dale L. Boger, Ph.D.* Richard and Alice Cramer Professor of Chemistry
Benjamin F. Cravatt, Ph.D.**** Assistant Professor
Philip Dawson, Ph.D.**** Assistant Professor
Gerald M. Edelman, M.D., Ph.D.***** Professor
Albert Eschenmoser, Ph.D.* Professor
Martha J. Fedor, Ph.D.** Associate Professor
M.G. Finn, Ph.D.* Associate Professor
Elizabeth D. Getzoff, Ph.D.+ Associate Professor
M. Reza Ghadiri, Ph.D.* Associate Professor
Kim D. Janda, Ph.D.++ Professor, Ely R. Callaway, Jr., Chair in Chemistry
Gerald F. Joyce, M.D., Ph.D.++ Associate Professor
Ehud Keinan, Ph.D.** Adjunct Professor
Jeffery W. Kelly, Ph.D.* Lita Annenberg Hazen Professor of Chemistry
Richard A. Lerner, M.D.++ President and CEO, Lita Annenberg Hazen Professor of Immunochemistry, Cecil H. and Ida M. Green Chair in Chemistry
Stephen P. Mayfield, Ph.D.**** Associate Professor
K.C. Nicolaou, Ph.D.* Aline W. and L.S. Skaggs Professor of Chemical Biology, Darlene Shiley Chair in Chemistry
Dmitry Rudkevich, Ph.D. Assistant Professor
Paul R. Schimmel, Ph.D.++ Professor
Peter Schultz, Ph.D.* Professor, Scripps Family Chair
K. Barry Sharpless, Ph.D.* W.M. Keck Professor
Subhash C. Sinha, Ph.D.** Associate Professor
Erik J. Sorensen, Ph.D.* Assistant Professor
John A. Tainer, Ph.D.** Professor
James R. Williamson, Ph.D.** Professor
Ian A. Wilson, D.Phil.** Professor
Chi-Huey Wong, Ph.D.* Ernest W. Hahn Professor and Chair in Chemistry
Peter E. Wright, Ph.D.** Professor, Cecil H. and Ida M. Green Investigator in Medical Research

Research Associates+++

Marcus Brody, Ph.D.
Young Lag Cho, Ph.D.
Stephen L. Craig, Ph.D.
Gebhard Haberhauer, Ph.D.
Takeharu Haino, Ph.D.
Steffi Körner, Ph.D.
Shihong Ma, Ph.D.
Tomás Martín, Ph.D.
Sandro Mecozzi, Ph.D.
Colin P. Nuckolls, Ph.D.
Jens-Uwe Peters, Ph.D.
Doris Pupowicz, Ph.D.
Adam R. Renslo, Ph.D.
Shoichi Saito, Ph.D.
Javier Santamaria, Ph.D.
Christoph Schalley, Ph.D.
Stephen Starnes, Ph.D.
Niels Svenstrup, Ph.D.
Fabio Tucci, Ph.D.
Alexander Wartini, Ph.D.
Paul Wash, Ph.D.

* Joint appointment in Department of Chemistry
** Joint appointment in Department of Molecular Biology
*** Joint appointment in Department of Molecular and Experimental Medicine
**** Joint appointment in Department of Cell Biology
***** Joint appointment in Department of Neurobiology
+ Joint appointments in Departments of Molecular Biology and Immunology
++ Joint appointments in Departments of Chemistry and Molecular Biology
+++ Research associates in the laboratories of staff other than Dr. Rebek are included in the lists of authors in the individual reports.

Investigators' Reports

Artificial Antibodies, Catalytic Antibodies, and Materials Tailored Specifically for Organic Synthesis
Bioorganic Chemistry, Neurochemistry, and Composite Materials
Bioorganic Chemistry
Bioorganic Chemistry of Proteins
Catalytic Nucleic Acids for Treating the Molecular Basis of Disease
Chemical Etiology of the Structure of Nucleic Acids
Chemical Physiology
Chemical Synthesis and Chemical Biology
Click Chemistry
Decoding Genetic Information in Translation
Design, Discovery, and Understanding of the Complex Properties of Self-Organized Chemical Networks
Evolution of Novel Enzymes
Expression of Antibodies in Microalgae
Freezing Molecules in Space and Time: Assembly and Encapsulation
From Catalytic Asymmetric Synthesis to the Regulation of Genes: In Vivo and In Vitro Evolution of Proteins
Intracellular RNA Assembly and Catalysis
Master Keys for Chemical Molecular Biology From Macromolecular Structures
Organic and Organometallic Chemistry and Catalysis
Principles of Protein Structure for Chemical Recognition, Complementarity, and Catalysis
Regulation, Function, and Signaling Mechanisms of Cell Adhesion Molecules
RNA Folding
Studies of Macromolecular Recognition by Multidimensional Nuclear Magnetic Resonance
Studies in Molecular and Experimental Medicine
Studies in Organic Synthesis and Bioorganic Chemistry
Synthetic and Bioorganic Chemistry
X-ray Crystallography of Therapeutically Important Macromolecules

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