March 06, 2014
Scientists Create Most Detailed Picture Ever of Membrane Protein Linked to Learning, Memory, Anxiety, Pain and Brain Disorders
Researchers at The Scripps Research Institute (TSRI) and Vanderbilt University have created the most detailed 3-D picture yet of a membrane protein that is linked to learning, memory, anxiety, pain and brain disorders such as schizophrenia, Parkinson’s, Alzheimer’s and autism.
March 04, 2014
New Probes from Scripps Research Institute Quantify Folded and Misfolded Protein Levels in Cells
Scientists at The Scripps Research Institute (TSRI) have invented small-molecule folding probes that enable them to quantify functional, normally folded and disease-associated misfolded conformations (shapes) of a protein-of-interest in cells under different conditions.
February 27, 2014
Scripps Research Institute Scientists Describe Deadly Immune ‘Storm’ Caused by Emergent Flu Infections
Scientists at The Scripps Research Institute (TSRI) have mapped key elements of a severe immune overreaction—a “cytokine storm”—that can both sicken and kill patients who are infected with certain strains of flu virus.
February 20, 2014
Scripps Florida Scientists Uncover Drug Resistance Mechanism that Could Impact Development of Two Antibiotic Drug Candidates
The use of antibiotics is often considered among the most important advances in the treatment of human disease. Unfortunately, though, bacteria are finding ways to make a comeback.
February 13, 2014
Scripps Florida Team Awarded $2.3 Million to Unlock Mysteries of Long-Term Memory
Scientists from the Florida campus of The Scripps Research Institute (TSRI) have been awarded approximately $2.3 million from the National Institute of Mental Health to study the processes involved in long-term memory and how deficits in those processes contribute to brain diseases.
February 09, 2014
Scripps Florida Scientists Invent Breakthrough Approach to Quickly Identify New Drug Candidates from Genome Sequence
In research that could ultimately lead to many new medicines, scientists from the Florida campus of The Scripps Research Institute (TSRI) have developed a potentially general approach to design drugs from genome sequence.
February 06, 2014
The Ultimate Decoy: Scripps Research Institute Scientists Find Protein that Helps Bacteria Misdirect Immune System
A team led by scientists at The Scripps Research Institute (TSRI) has discovered an unusual bacterial protein that attaches to virtually any antibody and prevents it from binding to its target.
February 05, 2014
Scripps Research Institute Scientists Create Potential Vaccine Ingredient for Childhood Respiratory Disease
Scientists at The Scripps Research Institute (TSRI) have invented a new method for designing artificial proteins, and have used it to make key ingredients for a candidate vaccine against a dangerous virus, respiratory syncytial virus (RSV), a significant cause of infant mortality.
January 30, 2014
Scripps Florida Scientist Awarded $1.8 Million to Develop New Approaches to Lung Cancer Therapy
Scientists from the Florida campus of The Scripps Research Institute (TSRI) have been awarded approximately $1.8 million from the National Cancer Institute of the National Institutes of Health to identify the signaling pathways that underlie lung cancer and to use this information to develop new therapeutic approaches.
January 28, 2014
Scripps Florida to Host Gala Luncheon in Celebration of ‘Decade of Discovery’
More than 350 business, political, community and scientific leaders from across Palm Beach County will gather at the Kravis Center on Thursday, February 6 to celebrate Scripps Florida’s 10th anniversary.
January 28, 2014
Community Invited to ‘CELLebrate’ Scripps Florida’s 10th Anniversary at Annual Science Festival
Event to offer exciting hands-on activities and awe-inspiring science demonstrations for all, with a special curriculum for school children
January 24, 2014
Scripps Research Institute Chemist Chi-Huey Wong Wins Prestigious Wolf Prize
Chi-Huey Wong, professor of chemistry at The Scripps Research Institute (TSRI), has won the 2014 Wolf Prize in Chemistry for his pioneering contributions to the synthesis of compounds vitally important to biology and medicine.
January 23, 2014
Scripps Florida Scientists Find Regulator of Amyloid Plaque Buildup in Alzheimer’s Disease
Scientists from the Florida campus of The Scripps Research Institute have identified a critical regulator of a molecule deeply involved in the progression of Alzheimer’s disease.
January 22, 2014
Scripps Florida Scientists Offer New Insight into Neuron Changes Brought About by Aging
How aging affects communication between neurons is not well understood, a gap that makes it more difficult to treat a range of disorders, including Alzheimer’s and Parkinson’s disease.
January 16, 2014
Preventing Cell Death from Infection: Scripps Research Institute Scientists Demonstrate Powerful Method to Find New Therapies
Scientists at The Scripps Research Institute (TSRI) have demonstrated the power of a new drug discovery technique, which allows them to find—relatively quickly and cheaply—antibodies that have a desired effect on cells.
January 13, 2014
Scripps Research Institute Scientists Develop Promising Drug Candidates for Pain, Addiction
Scientists from the Florida campus of The Scripps Research Institute (TSRI) have described a pair of drug candidates that advance the search for new treatments for pain, addiction and other disorders.
January 12, 2014
Scientists Solve 40-year Mystery of How Sodium Controls Opioid Brain Signaling
Scientists have discovered how the element sodium influences the signaling of a major class of brain cell receptors, known as opioid receptors.
January 09, 2014
Researchers Develop Test to Predict Early Onset of Heart Attacks
A new “fluid biopsy” technique that could identify patients at high risk of a heart attack by identifying specific cells as markers in the bloodstream has been developed by a group of researchers at The Scripps Research Institute (TSRI).
January 08, 2014
Nociceptin: Nature’s Balm for the Stressed Brain
Collaborating scientists at The Scripps Research Institute (TSRI), the National Institutes of Health (NIH) and the University of Camerino in Italy have published new findings on a system in the brain that naturally moderates the effects of stress.
January 08, 2014
Scripps Florida Scientists Identify Possible Key to Drug Resistance in Crohn’s Disease
Two-thirds to three-quarters of the estimated 700,000 Americans living with Crohn’s disease, an autoimmune condition that can disrupt the entire gastrointestinal tract, will require surgery at some point during their life.
January 02, 2014
Scripps Florida Scientists Uncover Most Detailed Picture Yet of Muscular Dystrophy Defect then Design Targeted New Drug Candidates
Scientists from the Florida campus of The Scripps Research Institute have revealed an atomic-level view of a genetic defect that causes a form of muscular dystrophy, myotonic dystrophy type 2, and have used this information to design drug candidates with potential to counter those defects—and reverse the disease.