April 27, 2015
TSRI Study: Nerve Cells and Blood Vessels in Eye ‘Talk’ to Prevent Disease
A new study from scientists at The Scripps Research Institute (TSRI) shows that nerve cells and blood vessels in the eye constantly “talk” to each other to maintain healthy blood flow and prevent disease.
April 21, 2015
TSRI Researchers Win $3.9 Million in Grants to Study Brain Regions that Suppress Cocaine and Alcohol Cravings
April 21, 2015–Scientists at The Scripps Research Institute (TSRI) have been awarded two grants to study brain mechanisms that actively suppress relapse associated with cocaine and alcohol addiction.
April 15, 2015
Scripps Florida Scientists Uncover How Molecule Protects Brain Cells in Parkinson’s Disease Model
Scientists from the Florida campus of The Scripps Research Institute have found how a widely known but little-studied enzyme protects brain cells in models of Parkinson’s disease.
April 14, 2015
TSRI Scientists Find that Nicotine Use Increases Compulsive Alcohol Consumption
Why do smokers have a five to ten times greater risk of developing alcohol dependence than nonsmokers?
April 09, 2015
Scripps Florida Scientists Awarded $1.2 Million to Find Drug Candidates that Could Treat a Wide Range of Cancers
Scientists from the Florida campus of The Scripps Research Institute (TSRI) have been awarded $1.2 million from the National Cancer Institute of the National Institutes of Health (NIH) to accelerate the development of drug candidates to curb one of the most important drivers of human cancer.
April 07, 2015
TSRI Scientists Find Molecular Trigger of Schizophrenia-Like Behaviors and Brain Changes
Scientists at The Scripps Research Institute (TSRI) have identified a molecule in the brain that triggers schizophrenia-like behaviors, brain changes and global gene expression in an animal model.
April 02, 2015
Scripps Florida Scientists Win $3.3 Million Grant to Accelerate Development of Treatments for Intellectual Disability, Autism, Epilepsy
Scientists from the Florida campus of The Scripps Research Institute (TSRI) have been awarded $3.3 million by the National Institutes of Health (NIH) to identify biomarkers to accelerate drug development for disorders including autism spectrum disorder, epilepsy and some types of intellectual disability.
March 31, 2015
Scripps Florida Scientists Reveal Unique Mechanism of Natural Product with Powerful Antimicrobial Action
Scientists from the Florida campus of The Scripps Research Institute (TSRI) have uncovered the unique mechanism of a powerful natural product with wide-ranging antifungal, antibacterial, anti-malaria and anti-cancer effects.
March 24, 2015
Scripps Research Institute Names Christopher A. Lee as Director of Philanthropy
The Scripps Research Institute (TSRI) has named Christopher A. Lee, formerly of PCI (Project Concern International), as director of philanthropy on the institute’s La Jolla, California campus.
March 23, 2015
TSRI Team Discovers Enzyme that Keeps Blood Stem Cells Functional to Prevent Anemia
Stem cells can generate any type of cell in the body, but they are inactive most of the time—and for good reason.
March 19, 2015
Scripps Florida Scientists Win $1.5 Million Grant to Develop New Cancer Drugs
Scientists from the Florida campus of The Scripps Research Institute (TSRI) have been awarded a $1.5 million grant from the National Institutes of Health (NIH) to develop drug candidates that could treat cancer and neurodegenerative disease.
March 17, 2015
New Compound Prevents Type 1 Diabetes in Animal Models—Before It Begins
Scientists from the Florida campus of The Scripps Research Institute (TSRI) have successfully tested a potent synthetic compound that prevents type 1 diabetes in animal models of the disease.
March 16, 2015
Scripps Florida Scientists Confirm Key Targets of New Anti-Cancer Drug Candidates
Ribosomes, ancient molecular machines that produce proteins in cells, are required for cell growth in all organisms, accomplishing strikingly complex tasks with apparent ease.
March 11, 2015
Scripps Research Institute Study Shows Two New Flu Strains Do Not Yet Easily Infect Humans
Scientists at The Scripps Research Institute (TSRI) have analyzed a key protein from two influenza strains that recently began causing sporadic infections among people in China and Taiwan.
March 10, 2015
TSRI Scientists Show that Proteins Critical In Day-Night Cycles Also Protect Cells from Mutations
A good night’s sleep does more than prevent yawning.
March 09, 2015
TSRI Scientists Reveal Structural Secrets of Nature's Little Locomotive
A team led by scientists at The Scripps Research Institute (TSRI) has determined the basic structural organization of a molecular motor that hauls cargoes and performs other critical functions within cells.
March 09, 2015
Scripps Research, Mayo Clinic Scientists Find New Class of Drugs that Dramatically Increases Healthy Lifespan
A research team from The Scripps Research Institute (TSRI), Mayo Clinic and other institutions has identified a new class of drugs that in animal models dramatically slows the aging process—alleviating symptoms of frailty, improving cardiac function and extending a healthy lifespan.
March 09, 2015
Go Meta: New Technique Expands Possibilities for Molecular Designers
Chemists at The Scripps Research Institute (TSRI) have developed a broadly useful technique for building new drug molecules and other chemical products.
March 03, 2015
Scripps Florida Scientists Find a Defect Responsible for Memory Impairment in Aging
Everyone worries about losing their memory as they grow older—memory loss remains one of the most common complaints of the elderly.
March 02, 2015
TSRI Scientists Find Clues to Cancer Drug Failure
Cancer patients fear the possibility that one day their cells might start rendering many different chemotherapy regimens ineffective.
March 02, 2015
FAU, Scripps Florida, Max Planck Announce Plans for Groundbreaking Research and Education Collaboration
One of Florida’s leading public research universities and two of the world’s premier research institutions will create one-of-a-kind education programs that will attract the best and brightest students to Palm Beach County, and transform Florida Atlantic University’s John D. MacArthur Campus in Jupiter into a hub of scientific inquiry, innovation and economic development.
February 26, 2015
TSRI Team Shows How Rare Antibody Targets Ebola and Marburg Viruses
Marburg virus is Ebola’s deadly cousin. The virus is up to 90 percent lethal—and doctors are desperate for tools to fight it.
February 25, 2015
New Study Shows Decreased Aggressive Behavior Toward Strangers in Autism Spectrum Disorder Model
While aggression toward caregivers and peers is a challenge faced by many individuals and families dealing with autism, there has been much speculation in the media over the possibility of generally heightened aggression in those diagnosed with autism spectrum disorder.
February 25, 2015
New TSRI Study Shows Safer Methods for Stem Cell Culturing
A new study led by researchers at The Scripps Research Institute (TSRI) and the University of California (UC), San Diego School of Medicine shows that certain stem cell culture methods are associated with increased DNA mutations.
February 18, 2015
Scripps Florida Scientists Announce Anti-HIV Agent So Powerful It Can Work in a Vaccine
In a remarkable new advance against the virus that causes AIDS, scientists from The Scripps Research Institute (TSRI) have announced the creation of a novel drug candidate that is so potent and universally effective, it might work as part of an unconventional vaccine.
February 12, 2015
Microbes Prevent Malnutrition in Fruit Flies—and Maybe Humans, Too
Microbes, small and ancient life forms, play a key role in maintaining life on Earth.
February 12, 2015
Scripps Florida Scientists' 'Mad Cow' Discovery Points to Possible Neuron Killing Mechanism Behind Alzheimer’s and Parkinson’s Diseases
Scientists from the Florida campus of The Scripps Research Institute (TSRI) have for the first time discovered a killing mechanism that could underpin a range of the most intractable neurodegenerative diseases such as Alzheimer’s, Parkinson’s and ALS.
February 10, 2015
TSRI Scientists Find New Cellular Pathway Defect in Cystinosis
Scientists at The Scripps Research Institute (TSRI) have identified a new cellular pathway that is affected in cystinosis, a rare genetic disorder that can result in eye and kidney damage.
February 06, 2015
Cow Immune System Inspires Potential New Therapies
To help people with hormone deficiencies, scientists at The Scripps Research Institute (TSRI) have developed a potential new therapy based on an unlikely model: immune molecules from cows.
February 05, 2015
Scripps Florida Scientists Discover a Key Pathway That Protects Cells Against Death by Stress
When it comes to protecting cells from death brought on by the calamities of environmental stress, the human body is particularly ingenious.
February 04, 2015
TSRI Scientists Find More DNA and Extra Copies of Disease Gene in Alzheimer’s Brain Cells
Scientists at The Scripps Research Institute (TSRI) have found diverse genomic changes in single neurons from the brains of Alzheimer’s patients, pointing to an unexpected factor that may underpin the most common form of the disease.
February 02, 2015
New TSRI Study Shows How Immune Cells Hone Their Skills to Fight Disease
The last time you were in the doctor’s office for a vaccine booster shot, did you wonder why you needed one?
January 29, 2015
San Diego Team Wins $1.7 Million Grant from Stem Cell Agency to Develop Quality Control Methods
A team at The Scripps Research Institute (TSRI) has won a $1,784,000 grant from the California Institute for Regenerative Medicine (CIRM).
January 27, 2015
Scripps Florida Scientists Establish that Drug Candidates Can Block Pathway Associated with Cell Death in Parkinson’s Disease
In a pair of related studies, scientists from the Florida campus of The Scripps Research Institute (TSRI) have shown their drug candidates can target biological pathways involved in the destruction of brain cells in Parkinson's disease.
January 21, 2015
Scripps Florida Scientists Move Closer to a Personalized Treatment Solution for Intellectual Disability
Scientists from the Florida campus of The Scripps Research Institute (TSRI) have produced an approach that completely protects animal models against a type of genetic disruption that causes intellectual disability, including serious memory impairments and altered anxiety levels.
January 14, 2015
Scripps Florida Scientists Develop Novel Platform for Treatment of Breast, Pancreatic Cancer
Scientists from the Florida campus of The Scripps Research Institute (TSRI) have identified a novel synthetic compound that sharply inhibits the activity of a protein that plays an important role in in the progression of breast and pancreatic cancers.
January 12, 2015
TSRI Scientists Design Nicotine Vaccine that Provokes Robust Immune Response
When a promising nicotine vaccine failed in clinical trials a few years ago, scientists from The Scripps Research Institute (TSRI) were determined to keep trying to help smokers overcome their addiction.
January 12, 2015
TSRI Scientists Discover Possible New Target for Treating Brain Inflammation
A team led by scientists at The Scripps Research Institute (TSRI) has identified an enzyme that produces a class of inflammatory lipid molecules in the brain.
January 08, 2015
TSRI Scientists Illuminate Mysterious Molecular Mechanism Powering Cells in Most Forms of Life
A team led by structural biologists at The Scripps Research Institute (TSRI) has taken a big step toward understanding the intricate molecular mechanism of a metabolic enzyme produced in most forms of life on Earth.