April 16, 2014
Scripps Florida Scientists Awarded $2 Million to Study Improvements in Anti-Diabetic Drug Design
Scientists from the Florida campus of The Scripps Research Institute have been awarded $2.1 million from the National Institutes of Health to study the therapeutic potential of safer and more effective alternatives to the current crop of anti-diabetic drugs, which have been limited in their use due to side effects including bone loss and congestive heart failure.
April 14, 2014
The Scripps Research Institute Announces ‘Scripps Advance,’ a New Drug Discovery Initiative
The Scripps Research Institute (TSRI) today announced the formation of Scripps Advance, a new drug discovery initiative to translate early-stage biomedical research projects, both internal and external to TSRI, into clinical development candidates.
April 10, 2014
Team Solves Decades-Old Mystery of How Cells Keep from Bursting
A team led by scientists at The Scripps Research Institute (TSRI) has identified a long-sought protein that facilitates one of the most basic functions of cells: regulating their volume to keep from swelling excessively.
April 09, 2014
Scripps Florida Scientists Win Grant to Study How Exposure to Prescription Pain Medication in the Womb Affects Developing Brain
Scientists from the Florida campus of The Scripps Research Institute have been awarded a $472,500 Cutting Edge Basic Research Award (CEBRA) by the National Institute on Drug Abuse (NIDA) of the National Institutes of Health to study models of the brain development of newborns who have been exposed—and become addicted—to prescription pain medication while still in the womb.
April 07, 2014
Scripps Florida Scientists Uncover Startling New Functional Details of Common Anti-Diabetic Drugs
Scientists thought they basically knew how the most common drugs used to treat type 2 diabetes worked, but a new study from the Florida campus of The Scripps Research Institute (TSRI) reveals unexpected new aspects of the process.
April 06, 2014
Scripps Research Institute Scientists Provide New Grasp of Soft Touch
A study led by scientists at The Scripps Research Institute (TSRI) has helped solve a long-standing mystery about the sense of touch.
April 02, 2014
Team Identifies Novel Biomarker for Head and Neck Cancer, Non-Small Cell Lung Cancer
A team led by a scientist from the Florida campus of The Scripps Research Institute (TSRI) has identified a new biomarker linked to better outcomes of patients with head and neck cancers and non-small cell lung cancer.
March 27, 2014
Scripps Florida Scientist Awarded $2.3 Million to Study Dengue Fever and Related Viruses
The outbreak of dengue fever that infected some 20 people in Florida’s Martin County late last year unnerved many who feared the tropical disease had once again established a foothold in Florida.
March 27, 2014
In Mapping Feat, Scripps Florida Scientists Pinpoint Neurons Where Select Memories Grow
Memories are difficult to produce, often fragile, and dependent on any number of factors—including changes to various types of nerves.
March 20, 2014
Consortium Led by Scripps Research Institute Scientist Wins Up to $28 Million from NIH to Find Best Proposed Ebola Treatment
The National Institutes of Health (NIH) has awarded a five-year grant of up to $28 million to establish a new center for excellence to find an antibody “cocktail” to fight the deadly Ebola virus.
March 13, 2014
Scripps Research Institute Scientists Discover a Better Way to Make Unnatural Amino Acids
Chemists at The Scripps Research Institute (TSRI) have devised a greatly improved technique for making amino acids not found in nature.
March 13, 2014
Stumbling Fruit Flies Lead Scientists to Discover Gene Essential for Sensing Joint Position
Scientists at The Scripps Research Institute (TSRI) have discovered an important mechanism underlying sensory feedback that guides balance and limb movements.
March 13, 2014
Scripps Florida Scientists Devise New, Lower Cost Method to Create More Usable Fuels
As the United States continues to lead the world in the production of natural gas, scientists from the Florida campus of The Scripps Research Institute (TSRI) have devised a new and more efficient method with the potential to convert the major components found in natural gas into useable fuels and chemicals—opening the door to cheaper, more abundant energy and materials with much lower emissions.
March 13, 2014
Renowned Biologist Karla Kirkegaard to Lead Scripps Florida’s Department of Infectious Diseases
Renowned virologist Karla Kirkegaard, PhD, will join the Florida campus of The Scripps Research Institute (TSRI) as chair of the Department of Infectious Diseases.
March 12, 2014
Building New Drugs Just Got Easier
Scientists at The Scripps Research Institute (TSRI) have developed a method for modifying organic molecules that significantly expands the possibilities for developing new pharmaceuticals and improving old ones.
March 06, 2014
Scientists Create Most Detailed Picture Ever of Membrane Protein Linked to Learning, Memory, Anxiety, Pain and Brain Disorders
Researchers at The Scripps Research Institute (TSRI) and Vanderbilt University have created the most detailed 3-D picture yet of a membrane protein that is linked to learning, memory, anxiety, pain and brain disorders such as schizophrenia, Parkinson’s, Alzheimer’s and autism.
March 04, 2014
New Probes from Scripps Research Institute Quantify Folded and Misfolded Protein Levels in Cells
Scientists at The Scripps Research Institute (TSRI) have invented small-molecule folding probes that enable them to quantify functional, normally folded and disease-associated misfolded conformations (shapes) of a protein-of-interest in cells under different conditions.
February 27, 2014
Scripps Research Institute Scientists Describe Deadly Immune ‘Storm’ Caused by Emergent Flu Infections
Scientists at The Scripps Research Institute (TSRI) have mapped key elements of a severe immune overreaction—a “cytokine storm”—that can both sicken and kill patients who are infected with certain strains of flu virus.
February 20, 2014
Scripps Florida Scientists Uncover Drug Resistance Mechanism that Could Impact Development of Two Antibiotic Drug Candidates
The use of antibiotics is often considered among the most important advances in the treatment of human disease. Unfortunately, though, bacteria are finding ways to make a comeback.
February 13, 2014
Scripps Florida Team Awarded $2.3 Million to Unlock Mysteries of Long-Term Memory
Scientists from the Florida campus of The Scripps Research Institute (TSRI) have been awarded approximately $2.3 million from the National Institute of Mental Health to study the processes involved in long-term memory and how deficits in those processes contribute to brain diseases.
February 09, 2014
Scripps Florida Scientists Invent Breakthrough Approach to Quickly Identify New Drug Candidates from Genome Sequence
In research that could ultimately lead to many new medicines, scientists from the Florida campus of The Scripps Research Institute (TSRI) have developed a potentially general approach to design drugs from genome sequence.
February 06, 2014
The Ultimate Decoy: Scripps Research Institute Scientists Find Protein that Helps Bacteria Misdirect Immune System
A team led by scientists at The Scripps Research Institute (TSRI) has discovered an unusual bacterial protein that attaches to virtually any antibody and prevents it from binding to its target.
February 05, 2014
Scripps Research Institute Scientists Create Potential Vaccine Ingredient for Childhood Respiratory Disease
Scientists at The Scripps Research Institute (TSRI) have invented a new method for designing artificial proteins, and have used it to make key ingredients for a candidate vaccine against a dangerous virus, respiratory syncytial virus (RSV), a significant cause of infant mortality.
January 30, 2014
Scripps Florida Scientist Awarded $1.8 Million to Develop New Approaches to Lung Cancer Therapy
Scientists from the Florida campus of The Scripps Research Institute (TSRI) have been awarded approximately $1.8 million from the National Cancer Institute of the National Institutes of Health to identify the signaling pathways that underlie lung cancer and to use this information to develop new therapeutic approaches.
January 28, 2014
Scripps Florida to Host Gala Luncheon in Celebration of ‘Decade of Discovery’
More than 350 business, political, community and scientific leaders from across Palm Beach County will gather at the Kravis Center on Thursday, February 6 to celebrate Scripps Florida’s 10th anniversary.
January 28, 2014
Community Invited to ‘CELLebrate’ Scripps Florida’s 10th Anniversary at Annual Science Festival
Event to offer exciting hands-on activities and awe-inspiring science demonstrations for all, with a special curriculum for school children
January 24, 2014
Scripps Research Institute Chemist Chi-Huey Wong Wins Prestigious Wolf Prize
Chi-Huey Wong, professor of chemistry at The Scripps Research Institute (TSRI), has won the 2014 Wolf Prize in Chemistry for his pioneering contributions to the synthesis of compounds vitally important to biology and medicine.
January 23, 2014
Scripps Florida Scientists Find Regulator of Amyloid Plaque Buildup in Alzheimer’s Disease
Scientists from the Florida campus of The Scripps Research Institute have identified a critical regulator of a molecule deeply involved in the progression of Alzheimer’s disease.
January 22, 2014
Scripps Florida Scientists Offer New Insight into Neuron Changes Brought About by Aging
How aging affects communication between neurons is not well understood, a gap that makes it more difficult to treat a range of disorders, including Alzheimer’s and Parkinson’s disease.
January 16, 2014
Preventing Cell Death from Infection: Scripps Research Institute Scientists Demonstrate Powerful Method to Find New Therapies
Scientists at The Scripps Research Institute (TSRI) have demonstrated the power of a new drug discovery technique, which allows them to find—relatively quickly and cheaply—antibodies that have a desired effect on cells.
January 13, 2014
Scripps Research Institute Scientists Develop Promising Drug Candidates for Pain, Addiction
Scientists from the Florida campus of The Scripps Research Institute (TSRI) have described a pair of drug candidates that advance the search for new treatments for pain, addiction and other disorders.
January 12, 2014
Scientists Solve 40-year Mystery of How Sodium Controls Opioid Brain Signaling
Scientists have discovered how the element sodium influences the signaling of a major class of brain cell receptors, known as opioid receptors.
January 09, 2014
Researchers Develop Test to Predict Early Onset of Heart Attacks
A new “fluid biopsy” technique that could identify patients at high risk of a heart attack by identifying specific cells as markers in the bloodstream has been developed by a group of researchers at The Scripps Research Institute (TSRI).
January 08, 2014
Nociceptin: Nature’s Balm for the Stressed Brain
Collaborating scientists at The Scripps Research Institute (TSRI), the National Institutes of Health (NIH) and the University of Camerino in Italy have published new findings on a system in the brain that naturally moderates the effects of stress.
January 08, 2014
Scripps Florida Scientists Identify Possible Key to Drug Resistance in Crohn’s Disease
Two-thirds to three-quarters of the estimated 700,000 Americans living with Crohn’s disease, an autoimmune condition that can disrupt the entire gastrointestinal tract, will require surgery at some point during their life.
January 02, 2014
Scripps Florida Scientists Uncover Most Detailed Picture Yet of Muscular Dystrophy Defect then Design Targeted New Drug Candidates
Scientists from the Florida campus of The Scripps Research Institute have revealed an atomic-level view of a genetic defect that causes a form of muscular dystrophy, myotonic dystrophy type 2, and have used this information to design drug candidates with potential to counter those defects—and reverse the disease.