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April 04, 2013
Scripps Research Institute Scientists Illuminate Elusive Mechanism of Widely Used Click Reaction
Scientists at The Scripps Research Institute (TSRI) have illuminated the mechanism at the heart of one of the most useful processes in modern chemistry.
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April 04, 2013
Scripps Research Institute Appoints Immunology Researcher to Faculty
The Scripps Research Institute (TSRI) has appointed Laura Solt as assistant professor at the Florida campus.
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April 03, 2013
Scripps Research Institute Scientists Identify First Potentially Effective Therapy for Human Prion Disease
Human diseases caused by misfolded proteins known as prions are some of most rare yet terrifying on the planet—incurable with disturbing symptoms that include dementia, personality shifts, hallucinations and coordination problems.
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April 02, 2013
Interactive Textbook from TSRI Scientists Offers New Kind of Resource for Both Academic and Industrial Chemists
Industrial chemists working toward new drugs and other goals, as well as organic chemistry students, now have a unique new resource to guide them through chemical challenges.
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March 28, 2013
New Vaccine-Design Approach Targets HIV and Other Fast-Mutating Viruses
A team led by scientists from The Scripps Research Institute and the International AIDS Vaccine Initiative has unveiled a new technique for vaccine design that could be particularly useful against HIV and other fast-changing viruses.
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March 27, 2013
Scripps Florida Scientists Awarded Special Collaborative Grant to Develop Anti-Addiction Medication
As part of an unprecedented national effort to develop new drugs to treat neurological disorders, scientists from the Florida campus of The Scripps Research Institute have been awarded an innovative grant from the National Institute of Neurological Disorders and Stroke to help people break their addiction to nicotine.
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March 25, 2013
Scripps Research Institute Scientists Uncover New Compounds that Dynamically Alter Cell Signaling and Expand Options for Developing Breast Cancer Treatments
Using a broad spectrum of analytical tools, scientists from the Florida campus of The Scripps Research Institute have uncovered a class of novel compounds that can alter cell signaling activity, resulting in a variety of responses including a strong anti-inflammatory effect. These findings could lead to new strategies for treating diseases such as breast cancer.
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March 25, 2013
New Lung Cancer Study Takes Page from Google’s Playbook
The same sort of mathematical model used to predict which websites people are most apt to visit is now showing promise in helping map how lung cancer spreads in the human body, according to a new study published in the journal Cancer Research.
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March 21, 2013
Study Reveals How Serotonin Receptors Can Shape Drug Effects from LSD to Migraine Medication
A team including scientists from The Scripps Research Institute (TSRI), the University of North Carolina at Chapel Hill and the Chinese Academy of Sciences has determined and analyzed the high-resolution atomic structures of two kinds of human serotonin receptor.
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March 21, 2013
Scripps Research Institute Study Underlines Potential of New Technology to Diagnose Disease
Researchers at The Scripps Research Institute (TSRI) in Jupiter, FL, have developed cutting-edge technology that can successfully screen human blood for disease markers.
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March 20, 2013
Philanthropist John Moores Gives $2 Million to The Scripps Research Institute to Develop River Blindness Field Test
Philanthropist, businessman and community leader John Moores has given The Scripps Research Institute (TSRI) approximately $2 million to fund the development of a new field test for Onchocerciasis, or river blindness, a parasitic infection that affects tens of millions of people in Africa, Latin America and other tropical regions.
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March 14, 2013
Scripps Research Institute Appoints Innovative Biotech Scientist to Cancer Biology Department
The Scripps Research Institute (TSRI) has appointed Mark Sundrud as an assistant professor in the Department of Cancer Biology.
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March 13, 2013
Scripps Research Institute and Takeda Pharmaceuticals Announce Expanded Research Collaboration
The Scripps Research Institute (TSRI) and the Takeda Pharmaceutical Company have announced plans to expand their recent research collaboration to search for new drug targets for a variety of diseases.
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February 25, 2013
Findings by Scripps Research Institute Scientists Disclose a New and Much Needed Test for River Blindness Infection
Scientists at The Scripps Research Institute have found a telltale molecular marker for Onchocerciasis or “river blindness,” a parasitic infection that affects tens of millions of people in Africa, Latin America and other tropical regions.
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February 24, 2013
Scientists Find Surprising New Influence on Cancer Genes
A new study led by scientists at The Scripps Research Institute shows how pseudogenes -- small stretches of DNA in the human genome thought to be non-coding “junk” DNA -- can regulate the activity of a cancer-related gene called PTEN.
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February 22, 2013
Noted Vaccine and Bioinformatics Researcher Joins The Scripps Research Institute
The Scripps Research Institute (TSRI) has appointed Jiang Zhu, PhD, to its faculty.
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February 21, 2013
Scripps Florida Scientists Awarded $2 Million to Study Tumor-Inhibiting Proteins
Scientists from the Florida campus of The Scripps Research Institute have been awarded just over $2 million from the National Institute of Neurological Disorders and Stroke of the National Institutes of Health to identify proteins that play key roles in tumor cell proliferation and to determine if targeting these proteins could result in the inhibition of tumor growth.
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February 20, 2013
Scripps Florida Scientist Awarded Prestigious Javits Neuroscience Investigator Award
Ron Davis, PhD, chair of the Neuroscience Department on the Florida campus of The Scripps Research Institute, has been selected to receive a prestigious $3.5 million Jacob K. Javits Neuroscience Investigator Award for his work on the complex biology of memory formation and the disorders that disrupt it.
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February 15, 2013
Scripps Research Institute Scientists Find Promising New Approach to Preventing Progression of Breast Cancer
Doctors currently struggle to determine whether a breast tumor is likely to shift into an aggressive, life-threatening mode—an issue with profound implications for treatment.
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February 07, 2013
Scripps Research Institute Professor Donna Blackmond Elected to National Academy of Engineering
Donna Blackmond, PhD, a professor in the Department of Chemistry at The Scripps Research Institute (TSRI), has been elected as a member in the prestigious National Academy of Engineering (NAE), it was announced today.
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February 07, 2013
Compound Developed by Scripps Florida Scientists Protects Heart Cells During and After Attack
Using two different compounds they developed, scientists from the Florida campus of The Scripps Research Institute (TSRI) have been able to show in animal models that inhibiting a specific enzyme protects heart cells and surrounding tissue against serious damage from heart attacks.
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February 06, 2013
Scripps Research Institute Scientists Discover How Chromosomes Keep Their Loose Ends Loose
Scientists at The Scripps Research Institute have discovered key details of how the protein TRF2 performs a crucial chromosome-protecting function. The finding represents a significant advance in cell biology and also has implications for our understanding of cancer and the aging process.
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February 04, 2013
Scripps Research Institute Scientists Find a Key Element of Lupus, Suggesting Better Drug Targets
A team led by scientists at The Scripps Research Institute (TSRI) has identified specific cellular events that appear key to lupus, a debilitating autoimmune disease that afflicts tens of millions of people worldwide.
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January 30, 2013
Scripps Research Institute Scientists Uncover a Previously Unknown Mechanism of Memory Formation
It takes a lot to make a memory. New proteins have to be synthesized, neuron structures altered.
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January 29, 2013
Scripps Research Institute Study Shows How Brain Cells Shape Temperature Preferences
While the wooly musk ox may like it cold, fruit flies definitely do not.
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January 25, 2013
Scripps Florida Team Awarded $1.2 Million to Develop Drug Candidates for Rheumatoid Arthritis and Neurodegenerative Disorders
Scientists from the Florida campus of The Scripps Research Institute (TSRI) have been awarded approximately $1.2 million from the National Institute of General Medical Sciences of the National Institutes of Health to identify, test and develop a series of drug candidates for a number of diseases, including rheumatoid arthritis, heart disease and several neurodegenerative disorders.
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January 24, 2013
Scripps Research Institute Appoints Memory Researcher to Faculty
The Scripps Research Institute (TSRI) has appointed Assistant Professor Seth Tomchik as a laboratory head on the Florida campus.
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January 23, 2013
Scripps Research Institute Names David Blinder to Key Fundraising Position
The Scripps Research Institute has appointed David Blinder, PhD, as senior vice president for external affairs at The Scripps Research Institute (TSRI).
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January 14, 2013
Scripps Research Institute Scientists Discover Structure of Protein Essential for Quality Control, Nerve Function
Using an innovative approach, scientists at The Scripps Research Institute (TSRI) have determined the structure of Ltn1, a recently discovered “quality-control” protein that is found in the cells of all plants, fungi and animals.
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January 10, 2013
Scripps Florida Scientists Uncover Potential Drug Target to Block Cell Death in Parkinson's Disease
Oxidative stress is a primary villain in a host of diseases that range from cancer and heart failure to Alzheimer’s disease, Amyotrophic Lateral Sclerosis and Parkinson’s disease. Now, scientists from the Florida campus of The Scripps Research Institute have found that blocking the interaction of a critical enzyme may counteract the destruction of neurons associated with these neurodegenerative diseases, suggesting a potential new target for drug development.
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January 08, 2013
Scripps Research Institute Chemists Devise Inexpensive, Benchtop Method for Marking and Selecting Cells
Chemists at The Scripps Research Institute (TSRI) have found an easier way to perform one of the most fundamental tasks in molecular biology.
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January 06, 2013
New Study Defines the Long-Sought Structure of a Protein Necessary for Cell-Cell Interaction
Scientists from the Florida campus of The Scripps Research Institute have solved part of the puzzle of how cells in all higher organisms bind to each other for the development, architecture, maintenance and function of tissues. The scientists have defined the structure of a protein essential to this process.
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January 03, 2013
Steroids that Only Nature Could Make on a Large Scale—Until Now
Scientists at The Scripps Research Institute have achieved a feat in synthetic chemistry by inventing a scalable method to make complex natural compounds known as “polyhydroxylated steroids.” These compounds, used in heart-failure medications and other drugs, have been notoriously problematic to synthesize in the laboratory.