2009
 
Bai, D., Ueno, L., and Vogt, P. K. (2009) Akt-mediated regulation of NFkB and the essentialness of NFkB for the oncogenicity of PI3K and Akt. Int J Cancer. 125(12), 2863-70.
Dannemann, N., Hart, J. R., Ueno, L., and Vogt, P. K. (2009) Phosphatidylinositol 4,5-bisphosphate (PIP2)-specific AKT1 is oncogenic. Int J Cancer. 2009 Oct 28. [Epub ahead of print]
Denley, A., Gymnopoulos, M., Kang, S., Mitchell, C., Vogt, P. K. (2009) Requirement of Phosphatidylinositol(3,4,5)Trisphosphate in Phosphatidylinositol 3-Kinase-Induced Oncogenic Transformation. Mol Cancer Res. 7(7):1132-1138.
Guo, H.-M., Minakawa, M., Ueno, L., Tanaka F. (2009) Synthesis and evaluation of a cyclic imine derivative conjugated to a fluorescent molecule for labeling of proteins. Bioorganic & Medicinal Chemistry Letters 19, 1210–1213.
Jiang, H., Bower, K. E., Beuscher, A. E., Zhou, B., Bobkov, A. A., Olson, A. J., and Vogt, P. K. (2009) Stabilizers of the Max Homodimer Identified in Virtual Ligand Screening Inhibit Myc Function. Mol. Pharmacol. 76(3), 491-502.
Shaginian, A., Whitby, L., Hong, S., Hwang, I., Farooqi, B., Searcey, M., Chen, J., Vogt, P. K., Boger, D. (2009) Design, synthesis, and evaluation of an alpha-helix mimetic library targeting protein-protein interactions. J Am Chem Soc. 131 (15), 5564-5572.
Shi, J., Vogt, P. K. (2009) Posttranslational regulation of Myc by promyelocytic leukemia zinc finger protein. Int J Cancer. 125(7), 1558-1565.
Shi, J., Stover, J. S., Whitby, L. R., Vogt, P. K., Boger, D. L. (2009) Small molecule inhibitors of Myc/Max dimerization and Myc-induced cell transformation. Bioorganic & Medicinal Chemistry Letters 19, 6038–6041.
Stover, J. S., Shi, J., Jin, W., Vogt, P. K., Boger, D. L. (2009) Discovery of inhibitors of aberrant gene transcription from libraries of DNA binding molecules: inhibition of LEF-1 mediated gene transcription and oncogenic transformation. J. Am. Chem. Soc. 131 (9), 3342-3348.
Vogt, P. K. (2009) A humble chicken virus that changed biology and medicine. Lancet Oncol. 10 (1), 96.
Vogt, P. K., Gymnopoulos, M., and Hart, J. R. (2009) PI 3-Kinase and Cancer: Changing Accents. Curr. Opin. Gen. Dev. 19(1), 12-17.
Vogt, P. K., Hart, J. R. (2009) Akt demoted in glioblastoma. Sci. Signal. 2 (67): pe26.
View the ABSTRACT and FULL TEXT on the Science Signaling web site.
Zhao, L., and Vogt, P. K. (2009) Hot-spot mutations in p110α of phosphatidylinositol 3-kinase (PI3K): differential interactions with the regulatory subunit p85 and with RAS. Cell Cycle, accepted.
Pubmed