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Bruce E. Torbett , Ph.D.
Position: Associate Professor
Education: MSPH., Ph.D., Dept. of Cellular, Molecular, & Developmental Biology, UCLA
Specialties: Biochemistry; flow cytometry; molecular biology; protein chemistry; virology.
email: betorbet@scripps.edu
Field(s): Immunology; lentiviral gene delivery; myeloid development/transcription; biochemical and structural virology.
Project(s): Evolution of drug resistance in HIV, HIV gag structure; the role of PU.1 in myeloid development; regulation of monocyte/macrophage function.
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Sebastian Breuer, Ph.D.
Position: Senior Research Associate
Education: Ph.D. Max Planck Institute of Molecular Physiology (Germany)
Specialties: Biochemistry; biophysics; flow cytomtery, protein chemistry; and virology.
email: breuer@scripps.edu
Field(s): Biochemical virology; HIV drug resistance and enzymology.
Project(s): The role of Gag mutations in altering cleavage efficacy; Gag assembly; development of assays for identifying inhibitors of HIV maturation.
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Max Chang, Ph.D.
Position: Senior Research Associate
Education: Ph.D. in Bioinformatics from the University of California, San Diego
Specialties: Computer programming; enzymology; and assay development.
email: mchang@scripps.edu
Field(s): Evolution of Drug Resistance in HIV.
Project(s): Allosteric inhibition of HIV protease; permissive mutations in protease; co-evolution of HIV protease and Gag; biochemical and viral fitness mechanisms.
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Joy Chen, Ph.D.
Position: Research Associate
Education: Ph.D. in Molecular Biology from Mt. Sinai School of Medicine.
Specialties: Flow cytometry; molecular biology.
email: joychen@scripps.edu
Field(s): Myeloid development; transcriptional regulation.
Project(s): Regulation; expression; activation of TREM2 and identification of its signaling partners.
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Karen Crain, B.S.
Position: Research Assistant
Education: B.S. in Biology from California State
University at Fresno
Specialties: Flow cytometry; molecular biology; virology.
email: kcrain@scripps.edu |
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Luisa Fernandez-Altuna, Ph.D.
Position: Research Associate
Education: Ph.D. in Biochemistry from the Institute of Biotechnology, UNAM, Mexico
Specialties: Biochemistry, molecular biology, virology.
email: luisae@scripps.edu
Field(s): HIV entry and viral fitness
Project(s): Gene screen and evaluation of novel cell surface molecules involved in HIV entry; biochemical and virological studies on
HIV-1 protease inhibitor resistance and viral fitness.
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Edward Kavalerchik, M.D.
Position: Clinical Scholar
Education: M.D. State University of New York at Stony Brook.
Specialties: Clinical medicine and cancer (AML) therapy; flow cytometry; hematology; myeloid gene regulation.
email: ekavaler@scripps.edu
Field(s): Genetic alterations in hematopoietic stem and progenitor cells that contribute to AML in the elderly.
Project(s): Exome sequencing of AML tissue from the elderly to determine genetic mutations; development of humanized mice for the study of AML.
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Deborah Noack, B.A.
Position: Research Assistant III
Education: B.A. Chemistry, University of California, San Diego.
Specialties: Molecular biology; protein chemisry; lentiviral vector development.
email: dnoack@scripps.edu
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Mike Scott, M.S.
Position: Research Assistant IV
Education: M.S., Analytical Chemistry, University of California, Riverside
Specialties: Proteomic Specialist; protein chemistry.
email: mscott@scripps.edu
Field(s): Proteomics, Targeted Metabolomics, Biomolecular Interaction Analysis using SPR (Biacore), Flow Cytometry
Project(s): HIV virion proteomics; Tagged tetherin proteomics; Membrane Proteomics of the mouse neurovascular unit as pertaining to the Blood Brain Barrier.
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Cathy (Xueqian) Wang, B.S.
Position: Graduate Student
Education: B.S., Biochemistry, The University of Alberta, Edmonton, Canada.
Specialties: Biochemistry; flow cytometry; molecular biology; virology.
email: xueqian@scripps.edu
Field(s): Lentiviral vector restriction of human hematopoietic stem cells.
Project(s): Understanding viral resistance mechanims in human hematopoietic stem cells.
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Jinyun Yuan, Ph.D.
Position: Research Associate
Education: Ph.D., Biochemistry, hematology, molecular biology, Peking Union Medical College, Tsinghua University, China
Specialties: Flow cytometry; stem cells/hematology; molecular biology; virology.
email: jyuan@scripps.edu
Field(s): Engineering restriction to HIV entry; understanding the contribution of drug-resistance protease and gag mutations that contribute to viral fitness .
Project(s): Cellular genomic modification with zinc fingers to disrupt HIV entry; understanding viral fitness.
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