Daniel Salomon, M.D.

BIOSKETCH:

Dr. Salomon is a Professor with Tenure at The Scripps Research Institute (TSRI) in the Department of Molecular and Experimental Medicine. He is the Co-Director of the Center for Organ and Cell Transplantation for Scripps Health at Scripps Green Hospital.

His undergraduate training was at Northwestern University (1969-1973) and medical graduate training at the Stritch-Loyola School of Medicine (1973-1976). He did his medical residency at Cedars-Sinai Medical Center, University of California, Los Angeles (1976-1979) and was Chief Medical Resident in 1980. Nephrology and transplantation immunology fellowships were done at the Brigham and Women's Hospital, Harvard Medical School (1980-1984) after which he became the Medical Director of the Kidney and Heart Transplant Programs at the University of Florida (1984-1990). In 1990, he moved to the Laboratory of Immunology at the National Institutes of Health to concentrate on basic laboratory work in molecular immunology and transplantation.

Dr. Salomon has trained 16 fellows/post-docs and is presently on the admissions Committee of the TSRI Graduate Program in Chemical and Structural Biology. He has published over 90 manuscripts, 36 chapters and edited 3 books. He has served on numerous national and international committees, including: Chair of the Regulatory Affairs Committee for the American Society of Gene Therapy; Executive Board member, Chair of the Program Committee, Chair of the Cell Transplantation Committee, and Chair of the Xenotransplantation Committee for American Society of Transplantation; Chair of the National Institutes of Health Islet Cell Resources Steering Committee; Chair of the NIH Genomics of Transplantation Cooperative Research Program Steering Committee and Chair of the Biological Response Modifiers Advisory Committee for the FDA.

Dr. Salomon's laboratory work is focused on various aspects of transplantation and immunology with a primary focus on the functional genomics of human kidney, liver and islet transplantation. One major objective is to discover biomarkers for the diagnosis of acute and chronic rejection, the management of immunosuppression, and prognostic markers for transplant outcomes. Another objective of the laboratory's efforts in functional genomics is to understand the multidimensionality of transcriptional regulation including microRNA regulation and alternative splicing in lymphocyte activation. Other areas of investigation include islet xenotransplantation, the molecular virology of Porcine Endogenous Retrovirus, therapeutic angiogenesis and applications of gene therapies to cell transplantation.


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BIOSKETCH: Dr. Salomon is a Professor with Tenure at The Scripps Research Institute (TSRI) in the Department of Molecular and Experimental Medicine. He is the Co-Director of the Center for Organ and Cell Transplantation for Scripps Health at Scripps Green Hospital. His undergraduate training was at Northwestern University (1969-1973) and medical graduate training at the Stritch-Loyola School of Medicine (1973-1976). He did his medical residency at Cedars-Sinai Medical Center, University of California, Los Angeles (1976-1979) and was Chief Medical Resident in 1980. Nephrology and transplantation immunology fellowships were done at the Brigham and Women's Hospital, Harvard Medical School (1980-1984) after which he became the Medical Director of the Kidney and Heart Transplant Programs at the University of Florida (1984-1990). In 1990, he moved to the Laboratory of Immunology at the National Institutes of Health to concentrate on basic laboratory work in molecular immunology and transplantation. Dr. Salomon has trained 16 fellows/post-docs and is presently on the admissions Committee of the TSRI Graduate Program in Chemical and Structural Biology. He has published over 90 manuscripts, 36 chapters and edited 3 books. He has served on numerous national and international committees, including: Chair of the Regulatory Affairs Committee for the American Society of Gene Therapy; Executive Board member, Chair of the Program Committee, Chair of the Cell Transplantation Committee, and Chair of the Xenotransplantation Committee for American Society of Transplantation; Chair of the National Institutes of Health Islet Cell Resources Steering Committee; Chair of the NIH Genomics of Transplantation Cooperative Research Program Steering Committee and Chair of the Biological Response Modifiers Advisory Committee for the FDA. Dr. Salomon's laboratory work is focused on various aspects of transplantation and immunology with a primary focus on the functional genomics of human kidney, liver and islet transplantation. One major objective is to discover biomarkers for the diagnosis of acute and chronic rejection, the management of immunosuppression, and prognostic markers for transplant outcomes. Another objective of the laboratory's efforts in functional genomics is to understand the multidimensionality of transcriptional regulation including microRNA regulation and alternative splicing in lymphocyte activation. Other areas of investigation include islet xenotransplantation, the molecular virology of Porcine Endogenous Retrovirus, therapeutic angiogenesis and applications of gene therapies to cell transplantation.