Kevin V. Morris pro-knowledge, not for profit lab dedicated to understanding the essence of life
Research and Review Articles
Barichievy S, Saayman S, Von Eije KJ, Morris KV, Arbuthnot P, Weinberg MS. The Inhibitory Efficacy of RNA POL III-Expressed Long Hairpin RNAs Targeted to Untranslated Regions of the HIV-1 5' Long Terminal Repeat. Oligonucleotides. Sep 26, 2007
Han J, Kim D, Morris KV. Promoter-associated RNA is required for RNA-directed transcriptional gene silencing in human cells. Proc Natl Acad Sci U S A. 2007 Jul 24;104(30):12422-7.
Kim DH, Villeneuve LM, Morris KV, Rossi JJ. Argonaute-1 directs siRNA-mediated transcriptional gene silencing in human cells. Nat Struct Mol Biol. 2006 Sep;13(9):793-7.
Morris KV, Rossi JJ. Lentivirus-mediated RNA interference therapy for human immunodeficiency virus type 1 infection. Hum Gene Ther. 2006 May;17(5):479-86. Review.
Weinberg MS, Morris KV. Are viral-encoded microRNAs mediating latent HIV-1 infection?
DNA Cell Biol. 2006 Apr;25(4):223-31.
Morris KV. Therapeutic potential of siRNA-mediated transcriptional gene silencing.
Biotechniques. 2006 Apr;Suppl:7-13. Review.
Weinberg MS, Villeneuve LM, Ehsani A, Amarzguioui M, Aagaard L, Chen ZX, Riggs AD, Rossi JJ, Morris KV. The antisense strand of small interfering RNAs directs histone methylation and transcriptional gene silencing in human cells. RNA. 2006 Feb;12(2):256-62. Epub 2005 Dec 22.
Morris KV. siRNA-mediated transcriptional gene silencing: the potential mechanism and a possible role in the histone code. Cell Mol Life Sci. 2005 Dec;62(24):3057-66. Review.
Morris KV, Looney DJ. Characterization of human immunodeficiency virus (HIV)-2 vector mobilization by HIV-1. Human Gene Therapy. 2005 Dec;16(12):1463-72.
Kawasaki, H., K. Taira, and Kevin V. Morris. siRNA induced
Transcriptional Gene Silencing in Mammalian Cells. Cell Cycle. 2005,
Vol 4, 3, e22-e28.
Kevin V. Morris. VIRx496 VIRxSYS. Current Opinion in Investigational
Drugs. 2005, Vol 6, 2,
Kevin V. Morris, Chris H. Chung, Werner Witke, and David J. Looney.
Inhibition of HIV-1 Replication by siRNA Targeting Conserved Regions of
gag/pol. RNA Biology, 2004, Vol 1, 2, pp32-35.
Kevin V. Morris, Simon W-L. Chan, Steven E. Jacobsen, David J. Looney.
Small interfereing RNA-induced transcriptional silencing in human
cells. Science, 2004, Vol. 305, 1289-1292.
Kevin V. Morris, James Gilbert, Flossie Wong-Staal, Mehdi Gasmi and
David J. Looney. Transduction of Primary cells by FIV cross-packaged
HIV vectors. Molecular Therapy 2004, Vol. 10/1, 181-190.
Kevin V. Morris and John J. Rossi. Anti-HIV-1 gene expressing
lentiviral vectors as an adjunctive therapy for HIV-1 infection.
Current HIV Research, 2004, 2, 79-92.
Kevin V. Morris, Robert A. Grahn, David J. Looney, and Niels C.
Pedersen. Characterization of a Mobilization Competent SIV Vector
containing a Ribozyme against SIV Polymerase. Journal of General
Virology, June 1 2004; 85 (6) 1489-1496.
Kevin V. Morris, Joanne Higgins, Xiaoyng Shen, Jonny T. Stine, Niels C.
Pedersen. The effects of HHV-8 vMIP-II on SIVmac251 infection and
replication competent and incompetent SIVmac239delta3 vectors.
Virus Research, 94 (2003) 103-112.
Kevin V. Morris. The fate of exogenous virus genes inserted into
the nef deletion site of SIVmac239∆3. Doctoral dissertation
accepted/published University of California Library, March 30, 2001.
Book Chapters
Kevin V. Morris and John J. Rossi. RNA interference in the production
of antiviral therapy. Handbook of Experimental Pharmacology. RNA
Towards Medicine, edited by Jan Barciszewski.
Kevin V. Morris. Transcriptional Gene Silencing in Human Cells:
Evolution, Mechanism, and Therapuetic Applications. Book entitled “Gene
Silencing: New Research” for Nova Science Publishers.
Kevin V. Morris and John J. Rossi. Combinatorial gene therapy for HIV
infection. Modern Biopharmaceuticals edited by Jörg Knäblein.
Hiroaki Kawasaki, Yoko Fukuda, Kazunari Taira, and Kevin V. Morris.
Suppression of Gene Expression via Chromatin Remodeling and the
siRNA-induced Silencing of Transcription. Gene Design and Delivery,
edited by Kazunari Taira
Kevin V. Morris and John J. Rossi. Combinatorial RNA Based Therapies
for the treatment of HIV infection. Modern Biopharmaceuticals - Design,
Development and Optimization“ (Wiley-VCH) is dedicated to Francis Crick
(1916 – 2004).
Kevin V. Morris and Flossie Wong-Staal. HIV-2 vectors. DNA
Delivery/Gene Transfer manual for Cold Springs Harbor, 2007, edited by
John J. Rossi and Ted Friedman.
Books
RNA And The Regulation Of Gene Expression;
A hidden layer of complexity. Edited by K. V. Morris