Index

ORIGINAL PUBLICATIONS; 1995 to 2004

• 117.  Furihata K, Kato K, Kanaji S, Rhadis-Baptista G, Kunicki TJ. 2004. Characterization of a soluble, recombinant convulxin that is an effective platelet agonist.  Submitted.
  Medline ID = Unavailable
• 116.  Kunicki TJ, Salomon DR, Nakagawa P, Crisler P, Harrison P, Nugent D.  2004.  Genetic predilection for aspirin-resistance in normal, healthy subjects and patients with ischemic coronary disease.  Submitted.
  Medline ID = Unavailable
• 115.  Kanaji S, Jacquelin B, Chang M, Nugent DJ, Kunicki TJ.  2004.  Transcriptional Regulation of Collagen Receptor Genes ITGA1and GP6 during Megakaryocyte Differentiation by CpG Methylation. Submitted.
  Medline ID = Unavailable
• 114.  Kunicki TJ, Salomon DR, Koziol J, Head S, Mondala T, Chismar JD, Baronciani L, Canciani MT, Federici AB.  2004.  An association of integrin gene haplotypes and bleedingseverity in Von Willebrand Disease (VWD) type 1 pedigrees.  Blood, Accepted. E-Publication.
  Medline ID = 15226188
• 113.  Nurden P, Jandrot-Perrus M, Combrie R, Winckler J, Arocas V, Lecut C, Pasquet JM, Kunicki TJ, Nurden AT.  2004.  Severe deficiency of glycoprotein VI in a patient with gray platelet syndrome.  Blood, 104(1):107-14.
  Medline ID = 15010364
• 112. Vasudevan S, Celikel R, Ruggeri ZM, Varughese KI, Kunicki TJ.  2004.  A single amino acid change in the binding pocket alters specificity of an anti-integrin antibody AP7.4 as revealed by its crystal structure.  Blood Cells and Molecular Disease, 32(1):176-81.
  Medline ID = 14757433
• 111.  Kanaji S, Kanaji T, Furihata K, Ware JL, Kunicki TJ.  2003.  Convulxin binds to native, human glycoprotein Ib (GPIb. J Biol Chem, 278(41):39452-60.)
  Medline ID = 12881531
• 110.  Kato K, Kanaji T, Russell S, Kunicki TJ, Furihata K, Kanaji S, Marchese P, Reininger A, Ruggeri ZM, Ware J.  2003.  The contribution of glycoprotein VI to stable platelet adhesion and thrombus formation illustrated by targeted gene deletion.  Blood, 102(5):1701-1707.
  Medline ID = 12738669
• 109.  Jacquelin B, Tuleja E, Kunicki TJ, Nurden P, Nurden AT.  2003.  Analysis of platelet membrane glycoprotein polymorphisms in Glanzmann thrombasthenia showed the French gypsy mutation in the alpha IIb gene to be strongly linked to the HPA-1b polymorphism in beta3.  J Thromb Haemost., 1(3):573-575.
  Medline ID = 12871468
• 108.  Furihata K, Kunicki TJ.  2002.  Characterization of the human GPVI gene (GP6) 5’-regulatory and promoter regions.  Arterioscler Thromb Vasc Biol., 22(10):1733-1739.
  Medline ID = 12377757
• 107.  Nurden AT, Ruan J, Pasquet J-M, Gauthier B, Combrié R, Kunicki T, Nurden P.  2002.  A novel ¹⁹⁶Leu to Pro substitution in the β3 subunit of the αIIbβ3 integrin in a patient with a variant form of Glanzmann thrombasthenia.  Platelets, 13:101-111.
  Medline ID = 11897046
• 106. Furihata K, Clemetson K, Deguchi H, and Kunicki TJ.  2001.  Variation in human platelet GPVI content modulates GPVI-specific prothrombinase activity.  Arterioscler Thromb Vasc Biol., 21(11):1857-1863.
  Medline ID = 11701478
• 105. Jacquelin B, Rozenshteyn D, Kanaji S, Koziol JA, Nurden AT and Kunicki TJ. 2001.   Characterization of inherited differences in transcription of the human integrin α₂ gene. J. Biol.  Chem., 276(26):23518-235243.
  Medline ID = 11313353
• 104.  Jacquelin B, Tarantino MD, Kritzik M, Rozenshteyn D, Koziol JA, Nurden AT and Kunicki TJ.  2001.  Allele-dependent transcriptional regulation of the human integrin α₂ gene. Blood, 97(6):1721-1726.
  Medline ID = 11238113
• 103. Di Paola J, Federici AB, Sacchi E, Canciani MT, Mannucci PM, Kritzik M, Kunicki TJ and Nugent DJ.  1999  Low platelet α₂β₁ levels in patients with von Willebrand Disease Type I represent an increased risk factor for bleeding.  Blood, 93(11):3578-3582.
  Medline ID = 10339461
• 102. Santoso S, Kunicki TJ, Kroll H, Haberbosch W and Gardemann A.  1999.  Association of the platelet glycoprotein Ia C₈₀₇T gene polymorphism with myocardial infarction in younger patients.Blood,  93(8):2449-2453.
  Medline ID = 10194421
• 101. Tomiyama Y, Shiraga M, Kinoshita S, Ambo H, Kurata Y, Matsuzawa Y and Kuncki TJ.  1998.  A Glanzmann thrombasthenia-like phenotype caused by a defect in inside-out signaling through the  integrin α_IIbβ₃. Thromb. Haemost., 80:735-742.
  Medline ID = 99057298
• 100. Kodandapani R, Veerapandian L, Ni C-Z, Chiou C-K, Whital R, Kunicki TJ and Ely KR. 1998. Conformational change in an anti-integrin antibody: Structure of OPG2 Fab bound to a b₃ peptide. Biochem. Biophys. Res. Comm. 251:61-6.
  Medline ID = 99009222
• 99. Kritzik M, Savage B, Nugent DJ, Santoso S, Ruggeri ZM and Kunicki TJ. 1998 Nucleotide polymorphisms in the a₂ gene define multiple alleles which are associated with differences in platelet a₂b₁. Blood, 92:2382-2388.
  Medline ID = 98421383
• 98. Brojer E, Ambo H, and Kunicki TJ. 1997. Expression of the murine antibody AP2 specific for the integrin a_IIbb₃ complex with the use of bacteriophage lambda vectors. Central European J. Immunol., 22:225-231.
  Medline ID = Unavailable
• 97. Kunicki TJ, Felding-Haberman B and Annis DS. 1997. Molecular determinants of RGD ligand specificity for b₃ integrins. J.Biol.Chem.,272:4103-4107.
  Medline ID = 97172476
• 96. Kunicki TJ, Kritzik M, Annis DS and Nugent DJ. 1997. Hereditary variation in platelet integrin a₂b₁ density is associated with two silent polymorphisms in the a₂ gene coding sequence. Blood, 89(6):1939-1943.
  Medline ID = 97211747
• 95. Humbert M, Nurden P, Bihour C, Pasquet J-M, Winckler J, Heilmann E, Savi P, Herbert J-M, Kunicki TJ and Nurden AT. 1996. Ultrastructural studies of platelet aggregates from human subjects receiving clopidogrel and from a patient with an inherited defect of an ADP-dependent pathway of platelet activation. Arteriosclerosis, 16:1532-1543.
  Medline ID = 97132002
• 94. McKay BS, Annis DS, Honda S, Christie D and Kunicki TJ. 1996. Molecular requirements for assembly and function of a minimized human integrin a_IIbb₃. J.Biol.Chem.,271:30544-30547.
  Medline ID = 97094790
• 93. Marcinkiewicz C, Rosenthal LA, Mosser DM, Kunicki TJ and Niewarowski S. 1996. Immunological characterization of eristostatin and echistatin binding sites on a_IIbb₃ and a_Vb₃ integrins. Biochemical Journal, 317:817-825.
  Medline ID = 96332475
• 92. Kunicki TJ, Annis DS, Deng YJ, Loftus JC and Shattil SJ. 1996. A molecular basis for affinity modulation of Fab ligand binding to the integrin a_IIbb₃ J.Biol.Chem., 271:20315-20321.
  Medline ID = 96355355
• 91. Humbert M, Kunicki TJ, Bihour C, Winckler J, Nurden AT and Nurden P. 1996. Visualization of activation-dependent epitopes on glycoprotein IIb-IIIa complexes of platelets stimulated by thrombin: Immunogold staining of ultrathin sections. Sem. Thromb. Hemost., 22:279-288.
  Medline ID = 96432986
• 90. Nurden P, Humbert M, Piotrowicz RS, Bihour C, Nurden AT and Kunicki TJ. 1996. The distribution of ligand-occupied a_IIbb₃ in resting and activated human platelets determined by expression of a novel class of ligand-induced binding site (LIBS) recognized by monoclonal antibody AP6. Blood, 88:887-899.
  Medline ID = 96309632
• 89. Schneppenheim R, Brassard J, Krey S, Budde U, Kunicki TJ, Holmberg L, Ware J and Ruggeri ZM. 1996. Defective dimerization of von Willebrand Factor subunits due to a Cys to Arg mutation in Type IID von Willebrand Disease. Pro. Natl. Acad. Sci. U.S.A., 93:3581-3586.
  Medline ID = 96195014
• 88. Pelletier AJ, Kunicki TJ and Quaranta V. 1996. Activation of the integrin a_Vb₃ involves a discrete cation-binding site that regulates conformation. J. Biol. Chem., 271:1364-1370.
  Medline ID = 8576125
• 87. Gruel Y, Nugent DJ, Kunicki TJ. 1995. Molecular specificity of anti IIb/IIIa human antibodies. Sem. Thromb. Hemost., 21(1):60-67.
  Medline ID = 95327967
• 86. Kunicki TJ, Ely KR, Kunicki T.C., Annis DS. 1995. The exchange of Arg-Gly-Asp (RGD) and Arg-Tyr-Asp (RYD) binding sequences in a recombinant murine Fab fragment specific for the integrin a_IIbb₃ does not alter integrin recognition. J. Biol. Chem., 270(28): 16660-16665.
  Medline ID = 95348086
• 85. Ely KR, Kunicki TJ, Kodandapani R. 1995 Common molecular scaffold for two unrelated RGD molecules. Protein Engineering, 8:823-827.
  Medline ID = 96227676
• 84. Pelletier AJ, Kunicki TJ, Ruggeri ZM, Quaranta V. 1995. The activation state of the integrin a_IIbb₃ affects outside-in signals leading to cell spreading and focal adhesion kinase phosphorylation. J.Biol.Chem., 270:18133-18140.
  Medline ID = 95355418
• 83. Ishida F, Gruel Y, Brojer E, Nugent DJ, Kunicki TJ. 1995. Repertoire cloning of a human IgG inhibitor of a_IIbb₃ function. The OG idiotype. Mol. Immunol., 32:613-622.
  Medline ID = 95371684
• 82. Kunicki TJ, Honda S, Dawson B, Honda Y, Ruan C and Aster RH. 1995. The Pl^A1 alloantigen system is a sensitive indicator of the structural integrity of the amino-terminal domain of the human integrin b₃ subunit. Blood Cells, Molecules and Diseases. 21:131-141.
  Medline ID = 96113694
• 81. Honda S, Honda Y, Bauer B, Ruan C and Kunicki TJ. 1995. The impact of three-dimensional structure on the expression of Pl^A alloantigens on human integrin b₃. Blood, 86:234-242.
  Medline ID = 95315542
• 80. Honda S, Tomiyama Y, Pelletier AJ, Annis DS, Honda Y, Orchekowski R, Ruggeri Z and Kunicki TJ. 1995. Topography of ligand-induced binding sites (LIBS), including a novel cation-sensitive epitope (AP5) at the amino-terminus, of the human integrin b₃ subunit. J.Biol.Chem., 270:11947-11954.
  Medline ID = 95263541
• 79. Kodandapani R, Veerapandian B, Kunicki TJ, Ely KR. 1995. Crystal structure of the OP-G2 Fab: An anti-receptor antibody that mimics an RGD cell adhesion site. In J. Biol. Chem., 270:2268-2273.
  Medline ID = 95138198

Index