Kristaps Jaudzems

jaudzems@scripps.edu

phone: +1 858 784 8013  
fax     : +1 858 784 8014 

Research Interest

Structure determination of proteins and complexes thereof using NMR spectroscopy; applications of NMR in drug discovery and studies of protein – ligand interactions.

Curriculum Vitae

2008 – present External Graduate Student, The Scripps Research Institute, La Jolla, CA, USA. Ph. D. Student (Chemistry), Riga Technical University, Riga, Latvia

2006 – 2008 M. Eng. Sc. (Chemical Technology), Riga Technical University, Riga, Latvia Research Assistant, Latvian Institute of Organic Synthesis (LIOS), Riga, Latvia. Thesis: “ Protein NMR spectroscopy and spatial structure: examples of DnaI and cyclic Sortase A”. Supervisor: Dr. Edvards Liepinsh

2002 – 2006 B. Sc. (Chemical Technology), Riga Technical University, Riga, Latvia.Thesis: “Synthesis of selectively protected analogues of glucose-6-phosphate”. Supervisor: Dr. Erika Bizdena

Publications

1. K. Loscha, K. Jaudzems, C. Ioannou, X. C. Su, F. Hill, G. Otting, N. Dixon, E. Liepinsh. Solution structure of the N-terminal domain of the Bacillus subtilis helicase-loading protein DnaI and interaction with the helicase. NAR, submitted.

2. K. Jaudzems, J. Kuka, A. Gutsaits, K. Zinovjevs, I. Kalvinsh, E. Liepinsh, E. Liepinsh, M. Dambrova. Inhibition of carnitine acetyltransferase by Mildronate, a regulator of energy metabolism. J. Enzyme Inhib. Med. Chem., in press.