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The Scripps Research Institute Email:psobies@scripps.edu |
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EDUCATION:
1972 to 1978 University of Lodz, Poland, Master of Science (1978)
1983 to 1988 University of Melbourne, Australia , Ph.D. (1989)
RESEARCH AND PROFESSIONAL EXPERIENCE:
1978 to 1981 Research Assistant undertaking Ph.D. program, Medical Academy of Lodz, Poland.
1982 to 1983 Research Assistant at Ludwig Institute for Cancer Research, Melbourne Branch, Australia.
1983 to 1988 Ph.D. student at Ludwig Institute for Cancer Research.
1989 to 1991 Research Fellow in the Centre for Early Human Development, Monash Medical Centre, Melbourne, Australia.
1991 to 1992 Research Fellow, University of Melbourne, School of Dental Science, Melbourne, Australia
1992 to 1995 Human Frontier Science Program Fellow at Laboratoire de Génétique Moléculaire des Eucaryotes, Institut de Génétique et de Biologie Moléculaire Cellulaire, Strasbourg, France
1996 to 1999 Research Fellow, Imperial College School of Medicine, Molecular Genetics, A. Fleming Bldg., South Kensington, London, UK
2000 to 2002 Senior Experimental Officer, University of Manchester, Manchester, UK
2002 to Present Director for Mouse Genetic/Transgenetic Core, The Scripps Research Institute, California, USA
PUBLICATIONS:
Sobieszczuk P., K. Furtak K., Skowronski J. and Plucienniczak A. [1980] Hybridization of restriction fragments derived from calf satellite I DNA. Acta Biochim. Polonica, 2, 303-308.
Stanley E., Metcalf D., Sobieszczuk P., Gough N. M. and Dunn A. [1985] The structure and expression of the murine gene encoding granulocyte - macrophage colony stimulating factor: evidence for utilisation of alternative promoters. EMBO J., 4, 2569-2573.
Gonda T. J., Cory S., Sobieszczuk P., Holtzman D. and Adams J. [1987] Generation of altered transcripts by retroviral insertion within the c-myb gene in two murine monocytic leukemias. J. Virol., 61, 2754-2763.
Sobieszczuk P., Gonda T. J. and Dunn A. R. [1989] Structure and biological activity of the transcriptional initiation sequences of the murine c-myb oncogene. Nucleic Acids Research 17, 9593-9611.
Toh B-H., Gleeson P. A., Simpson R. J, Moritz R. L., Callaghan J. M., Goldkorn I., Jones C. M., Martinelli T. M., Mu F-T., Humphris D. C., Pettitt J.M., Mori Y., Masuda T., Sobieszczuk P., Weinstock J., Mantamadiotis T. and Baldwin G. S. [1990] The 60-to 90-kDa parietal cell autoantigen associated with autoimmune gastritis is a b subunit of the gastric H+/K+ - ATPase (proton pump). Proc. Natl. Acad. Sci. USA 87, 6418-6422.
Mantamadiotis T., Sobieszczuk P., Weinstock J. and Baldwin G. S. [1993] Nucleotide sequence encoding a novel member of the hydratase/dehydrogenase family. Biochimica et Biophysica Acta 1170, 211-215.
Giovane A., Pintzas A., Maira S-M., Sobieszczuk P. and Wasylyk B. [1994] Net, a new ets transcription factor that is activated by Ras. Genes and Development 8, 1502-1513.
Wasylyk C., Sobieszczuk P., Maira S-M. and Wasylyk B. [1994] Reversion of ras transformed cells by ets trans-dominant mutants. Oncogene 9, 3665-3673.
Sobieszczuk P., Giovane A., Mattei M-G., Mignon C. and Wasylyk B. [1995] Locations of the ets subfamily members net, elk1 and sap1 on three homologous regions of the mouse and human genomes. Genomics 29, 769-772
Giovane A., Sobieszczuk P., Ayadi A., Maira S-M. and Wasylyk B. [1997] Net-b, a Ras-insensitive factor that forms ternary complexes with Serum Response Factor on the Serum Response Element of the fos promoter. Mol. Cell. Biol. 17, 5667-5678
Ayadi A., Zheng H., Sobieszczuk P., Buchwalter G., Moerman P., Alitalo K. and Wasylyk B. [2001] Net targeted mutant mice develop a vascular phenotype and up-regulate egr-1. EMBO J. 20, 5139-5152
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