[89] [90] [91] [92] [93] [94] [95] [96] [97] [98] [99] [00] [01] [02] [03] [04] [05] [06]
2006
87 Paul, N., Springsteen, G. & Joyce, G.F. "Conversion of a Ribozyme to a Deoxyribozyme through In Vitro Evolution" Chem. & Biol. 13, 329-338. ABSTRACT
2005
86 Oberhuber, M. & Joyce, G.F. "A DNA-Templated Aldol Reaction as a Model for the Formation of Pentose Sugars in the RNA World" Angew. Chem. Int. Ed. 44, 7580-7583. ABSTRACT
85 Johns, G.C. & Joyce, G.F. "The Promise and Peril of Continuous IN Vitro Evolution" J. Mol. Evol. 61, 253-263. ABSTRACT

2004

84 Kim, D-E. & Joyce, G.F. "Cross-catalytic replication of an RNA ligase ribozyme" Chem. & Biol. 11, 1505-1512. ABSTRACT
83 Paul, N. & Joyce, G.F. "Minimal self-replicating systems" Curr. Opin. Chem. Biol. 8, 634-639. ABSTRACT
82 Springsteen, G. & Joyce, G.F. "Selective derivatization and sequestration of ribose from a prebiotic mix" J. Am. Chem. Soc. 126, 9578-9583 ABSTRACT
81 Joyce, G.F. "Directed evolution of nucleic acid enzymes" AR Reviews In Advance 73, 791–836 ABSTRACT
80 Shih, W.M., Quispe, J.D. & Joyce, G.F. "A 1.7-kilobase single-stranded DNA that folds into a nanoscale octahedron" Nature 427, 618–621 ABSTRACT

2003

79 Kuhne, H. & Joyce, G.F. "Continuous in vitro evolution of ribozymes that operate under conditions of extreme pH" J. Mol. Evol. 57, 292–298 ABSTRACT
78 Kumar, R.M. & Joyce, G.F. "A modular, bifunctional RNA that integrates itself into a target RNA" Proc. Natl. Acad. Sci. USA 100, 9738–9743 ABSTRACT
77 Kuhns, S. & Joyce, G.F. "Perfectly Complementary Nucleic Acid Enzymes" J. of Mol. Evol. 56, 711–717. ABSTRACT
76 Paul, N. & Joyce, G.F. "Self-replication" Curr. Biol. 13, R46.
75 McGinness, K.E. & Joyce, G.F. "In search of an RNA replicase ribozyme" Chem. & Bio. 10, 5–14. ABSTRACT

2002

74 Reader, J.S. & Joyce, G.F. "A Ribozyme composed of only two different nucledotides" Nature 420, 841–844. ABSTRACT
73 Joyce, G.F. "Booting up life" Nature 420, 278–279.
72 Ordoukhanian, P. & Joyce, G.F. "RNA-cleaving DNA enzymes with altered regio- or enantioselectivity" J. Am. Chem. Soc. 124, 12499–12506. ABSTRACT
71 Paul, N. & Joyce, G.F. "A self-replicating ligase ribozyme" Proc. Natl. Acad. Sci. USA 99, 12733–12740. ABSTRACT  
70 Joyce, G.F. "The antiquity of RNA based evolution" Nature Insight 418, 214–221. ABSTRACT  
69 McGinness, K.E., Wright, M.C. & Joyce, G.F. "Continuous in vitro evolution of a ribozyme that catalyzes three successive nucleotidyl addition reactions" Chem. & Biol. 9, 585–596. ABSTRACT  
68 McGinness, K.E. & Joyce, G.F. "RNA-catalyzed RNA ligation on an external RNA template" Chem. & Biol. 9, 297–307. ABSTRACT  
67 McGinness, K.E. & Joyce, G.F. "Substitution of ribonucleotides in the T7 RNA polymerase promoter element" J. Biol. Chem. 7, 2987–2991. ABSTRACT   

2001
66 Rogers, J. & Joyce, G.F. "The effect of cytidine on the structure and function of an RNA ligase ribozyme" RNA 7, 395–404. ABSTRACT   
66a Joyce, G.F. "RNA cleavage by 10-23 DNA Enzyme" Methods in Enzymology, 341, 503–517.

2000
65 Sheppard, T.L., Wong, C. & Joyce, G.F. "Nucleoglycoconjugates: design and synthesis of a new class of DNA-carbohydrate conjugates" Angew. Chem. Int. Ed. 39, 3660–3663.
64 Joyce, G.F. "Ribozyme evolution at the crossroads" Science 289, 401–402
63 Sheppard, T.L., Ordoukhanian, P. & Joyce, G.F. "A DNA enzyme with N-glycosylase activity" Proc. Natl. Acad. Sci. USA 97, 7802–7807. ABSTRACT    
62 Nowakowski, J., Shim, P.J., Stout, C.D. & Joyce, G.F. "Alternative confirmations of a nucleic acid four-way junction" J. Mol. Biol. 300, 93–102. ABSTRACT    
61 Joyce, G.F. "Employing DNAzymes to target bcr-abl mRNA in chronic myelogenous leukemia" Blood Cells, Molecules, and Diseases 26, 60–61.
60 Santoro, S.W., Joyce, G.F., Sakthivel, K., Gramatikova, S. & Barbas, C.F. "RNA cleavage by a DNA enzyme with protein-like functionality" J. Am. Chem. Soc. 122, 2433–2439. ABSTRACT    

1999
59 Jaeger, L., Wright, M.C. & Joyce, G.F. "A complex ligase ribozyme evolved in vitro from a group I ribozyme domain" Proc. Natl. Acad. Sci. USA 96, 14712–14717. ABSTRACT  
58 Ordoukhanian, P. & Joyce, G.F. "A molecular description of the evolution of resistance" Chem. Biol. 6, 881–889. ABSTRACT   
57 Rogers, J. & Joyce, G.F. "A ribozyme that lacks cytidine" Nature 402, 323–325.ABSTRACT    
56 Nowakowski, J., Shim, P.J., Joyce, G.F.& Stout, C.D. "Crystallization of the 10-23 DNA enzyme using a combinatorial screen of paired oligonucleotides" Acta. Cryst. D55, 1885–1892. ABSTRACT    
55 Joyce, G.F. "The Counterforce" Curr. Biol. 9, R500–501.  
54 Kumar, R.M. & Joyce, G.F. "Developing ribozymes for therapeutic application through in vitro evolution" In Intracellular Ribozyme Technology: Protocols and Applications, Horizon Scientific Press, Norfolk, England, 21–35. ABSTRACT 
53 Arrhenius, G., Bada, J.L., Joyce, G.F., Lazcano, A., Miller, S. & Orgel, L.E. "Origin and ancestor: separate environments" (letter) Science 283, 792.
52 Nowakowski, J., Shim, P.J., Prasad, G.S., Stout, C.D. & Joyce, G.F. "Crystal structure of an 82-nucleotide RNA-DNA complex formed by the 10-23 DNA enzyme" Nature Struct. Biol. 6, 151–156. ABSTRACT    
51 Joyce, G.F. & Orgel, L.E. "Prospects for understanding the origin of the RNA world" In The RNA World, Second Edition, Cold Spring Harbor Laboratory Press, Cold Spring Harbor, NY, 49–77. ABSTRACT
50 Joyce, G.F. "Appendix 3: Reactions Catalyzed by RNA and DNA Enzymes", The RNA World, Second Edition, Cold Spring Harbor Laboratory Press, Cold Spring Harbor, NY, 687–689.

1998
49 Santoro, S.W. & Joyce, G.F. "Mechanisms and Utility of an RNA-Cleaving DNA Enzyme" Biochemistry 37, 13330–13342. ABSTRACT    
48 Joyce, G.F. "Nucleic acid enzymes: Playing with a fuller deck" Proc. Natl. Acad. Sci. USA, 95, 5845–5847.  
47 Joyce, G.F. & Orgel, L.E. "The origins of life - a status report" Am. Biol. Teacher, 60, No. 1, 10–12. ABSTRACT 

1997
46 Bruick, R.K., Koppitz, M., Joyce, G.F. & Orgel, L.E. "A simple procedure for constructing 5'-amino-terminated oligodeoxynucleotides in aqueous solution" Nucleic Acids Res. 25, 1309–1310. ABSTRACT    
45 Hendrix, M., Priestley, E.S., Joyce, G.F., & Wong, C. "Direct observation of aminoglycoside-RNA interactions by surface plasmon resonance" J. Am. Chem. Soc. 119, 3641–3648. ABSTRACT    
44 Wright, M.C. & Joyce, G.F. "Continuous in vitro evolution of catalytic function" Science 276, 614–617. ABSTRACT    
43 Santoro, S.W. & Joyce, G.F. "A general purpose RNA-cleaving DNA enzyme" Proc. Natl. Acad. Sci. USA 94, 4262–4266. ABSTRACT    
42 Joyce, G.F. "Evolutionary Chemistry: getting there from here" (commentary) Science 276, 1658–1659.

1996
41 Bruick, R.K., Dawson, P.E., Kent, S.B.H., Usman, N. & Joyce, G.F. "Template-directed ligation of peptides to oligonucleotides" Chem. Biol. 3, 49–56. ABSTRACT  
40 Joyce, G.F. "Building the RNA world" (commentary) Curr. Biol. 6, 965–967.  
39 Raillard, S.-A. & Joyce, G.F. "Targeting sites within HIV-1 cDNA with a DNA-cleaving ribozyme" Biochemistry 36, 11693–11701. ABSTRACT    
38 Tsang, J. & Joyce, G.F. "in vitro evolution of randomized ribozymes" In Methods in Enzymology, vol. 267, J. Abelson (ed.), Academic Press, Orlando, pp. 410–426.
37 Tsang, J. & Joyce, G.F. "Specialization of the DNA-cleaving activity of a group I ribozyme through in vitro evolution" J. Mol. Biol. 262, 31–42. ABSTRACT    

1995
36 Breaker, R.R. & Joyce, G.F. "A DNA enzyme with Mg2+-dependent RNA phosphoesterase activity" Chem. Biol. 2, 655–660. ABSTRACT  
35 Breaker, R.R. & Joyce, G.F. "Self-incorporation of coenzymes by ribozymes" J. Mol. Evol. 40, 551–558. ABSTRACT   
34 Dai, X., De Mesmaeker, A. & Joyce, G.F. "Cleavage of an amide bond by a ribozyme" Science 267, 237-240; see also Science 267, 18–19, 1996. ABSTRACT  
33 Joyce, G.F. "The RNA world: life before DNA and protein" In Extraterrestrials, Where are They?, B. Zuckerman & M.H. Hart (eds.), Cambridge University Press, Cambridge, 139–151. ABSTRACT 

1994
32 Breaker, R.R., Banerji, A. & Joyce, G.F. "Continuous in vitro evolution of bacteriophage RNA polymerase promoter elements" Biochemistry 33, 11980–11986. ABSTRACT
31 Breaker, R.R. & Joyce, G.F. "A DNA enzyme that cleaves RNA" Chem. Biol. 1, 223–229. ABSTRACT
30 Breaker, R.R. & Joyce, G.F. "Emergence of a replicating species from an in vitro RNA evolution reaction" Proc. Natl. Acad. Sci. USA 91, 6093–6097. ABSTRACT
29 Breaker, R.R. & Joyce, G.F. "Inventing and improving ribozyme function: rational design versus iterative selection methods" Trends Biotechnol. 12, 268–275. ABSTRACT
28 Breaker, R.R. & Joyce, G.F. "Minimonsters: evolutionary byproducts of in vitro RNA amplification" In Proceedings of the NATO Conference on Self-Reproduction of Supramolecular Structures, Maratea, Italy, September 12-16, 1993, G.R. Fleischaker, S. Colonna & P.L. Luisi (eds.), Kluwer Academic Press, Dordrecht, The Netherlands, pp. 127–135
27 Cadwell, R.C. & Joyce, G.F. "Mutagenic PCR" PCR Methods Appl. 3, S136–S140. ABSTRACT
26 Chakrabarti, A.C., Breaker, R.R., Joyce, G.F. & Deamer, D.W. "Production of RNA by a polymerase protein encapsulated within phospholipid vesicles" J. Mol. Evol. 39, 555–559. ABSTRACT
25 Joyce, G.F. "Foreward" In Origins of Life: The Central Concepts, D.W. Deamer & G.R. Fleischacker (eds.), Jones and Bartlett Publishers, Boston, pp. xi–xii.
24 Joyce, G.F. "in vitro evolution of nucleic acids" Curr. Opin. Struct. Biol. 4, 331–336. ABSTRACT
23 Li, T., Zeng, Z., Estevez, V.A., Baldenius, K.U., Nicolaou, K.C. & Joyce, G.F. "Carbohydrate minor groove interactions in the binding of calicheamicin g1I to duplex DNA" Journal of the American Chemical Society 116, 3709–3715. ABSTRACT
22 Tsang, J. & Joyce, G.F. "Evolutionary optimization of the catalytic properties of a DNA-cleaving ribozyme" Biochemistry 33, 5966–5973. ABSTRACT

1993
21 Joyce, G.F. "Climbing Darwin's ladder" (commentary) Current Biol. 3, 703–704
20 Joyce, G.F. "Evolution of catalytic function" Pure & Appl. Chem. 65, 1205–1212. ABSTRACT
19 Joyce, G.F. & Orgel, L.E. "Prospects for understanding the origin of the RNA world" In The RNA World, R.F. Gesteland & J.F. Atkins (eds.), Cold Spring Harbor Laboratory Press, Cold Spring Harbor, NY, 1–25.
18 Lehman, N. & Joyce, G.F. "Evolution in vitro of an RNA enzyme with altered metal dependence" Nature 361, 182–185. ABSTRACT
17 Lehman, N. & Joyce, G.F. "In vitro Evolution: Analysis of a Lineage of Ribozymes" Curr. Biol. 3, 723–734. ABSTRACT

1992
16 Beaudry, A.A. & Joyce, G.F. "Directed evolution of an RNA enzyme" Science 257, 635–641. ABSTRACT
15 Cadwell, R.C. & Joyce, G.F. "Randomization of genes by PCR mutagenesis" PCR Methods Appl. 2, 28–33. ABSTRACT
14 Joyce, G.F. "Directed molecular evolution" Sci. Am. 267(6), 90–97.
13 Joyce, G.F. "Selective amplification techniques for optimization of ribozyme function" In Antisense RNA and DNA, J.A.H. Murray (ed.), Modern Cell Biology Series, Alan R. Liss, New York, 353–372. ABSTRACT
12 Nicolaou, K.C., Tsay, S.-C., Suzuki, T. & Joyce, G.F. "DNA-carbohydrate interactions. Specific binding of the calicheamicin g1I oligosaccharide with duplex DNA" J. Amer. Chem. Soc. 114, 7555–7557.

1991
11 Joyce, G.F. "RNA today" (meeting review), New Biologist 3, 565–569. ABSTRACT
10 Joyce, G.F. "The rise and fall of the RNA world", New Biologist 3, 399–407. ABSTRACT
9 obertson, D.L. & Joyce, G.F. "The catalytic potential of RNA" In Molecular Evolution on Rugged Landscapes: Proteins, RNA and the Immune System, A.S. Perelson & S.A. Kauffman (eds.), Santa Fe Institute Studies in the Sciences of Complexity, vol. 8, Addison-Wesley, Redwood City, 265–277.

1990
8 Beaudry, A.A. & Joyce, G.F. "Minimum secondary structure requirements for catalytic activity of a self-splicing group I intron" Biochemistry 29, 6534–6539. ABSTRACT
7 Joyce, G.F. "In the beginning" (book review), Nature 346, 806
6 Robertson, D.L. & Joyce, G.F. "Selection in vitro of an RNA enzyme that specifically cleaves single-stranded DNA" Nature 344, 467–468. ABSTRACT

1989
5 Joyce, G.F. "Amplification, mutation, and selection of catalytic RNA" Gene 82, 83–87. ABSTRACT
4 Joyce, G.F. "Building the RNA world: evolution of catalytic RNA in the laboratory" In Molecular Biology of RNA, T.R. Cech (ed.), UCLA Symposia on Molecular and Cellular Biology, vol. 94, Alan R. Liss, New York, 361–371.
3 Joyce, G.F. "RNA evolution and the origins of life" Nature 33, 217–224. ABSTRACT
2 Joyce, G.F. & Inoue, T. "A novel technique for the rapid preparation of mutant RNAs" Nucleic Acids Res. 17, 711–722. ABSTRACT
1 Joyce, G.F., van der Horst, G. & Inoue, T. "Catalytic activity is retained in the Tetrahymena group I intron despite removal of the large extension of element P5" Nucleic Acids Res. 17, 7879–7889. ABSTRACT