Polyamide Localization

in the Nucleus of Cultured Cells

 

Flourescent DNA-binding polyamide-bodipy conjugate (green) staining the nucleus and chromosomes in cultured KYO1 cells.

Cells were incubated with 2 microM polyamide in culture medium for 16 hours prior to visualization by deconvolution microscopy.

Mitochondria are stained with MitoTraker (red) as a cytoplasmic marker.

Click here to view the movie of polyamide localization in the nucleus of cultured cells