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The Mandyam Lab

Publications

Mandyam CD and Koob GF. The addicted brain craves new neurons: putative role for adult-born progenitors in promoting recovery. In press, Trends Neurosci. 2012

Recinto P, Samant AR, Chavez G, Kim A, Yuan CJ, Soleiman M, Grant Y, Edwards S, Wee S, Koob GF, George O, Mandyam CD. Levels of Neural Progenitors in the Hippocampus Predicts Memory Impairment and Relapse to Drug Seeking as a Function of Excessive Methamphetamine Self-Administration. Neuropsychopharmacology. 2011 Dec 28. doi: 10.1038/npp.2011.315. [Epub ahead of print]

Yuan CJ, Quiocho JM, Kim A, Wee S, Mandyam CD. Extended access methamphetamine decreases immature neurons in the hippocampus which results from loss and altered development of neural progenitors without altered dynamics of the S-phase of the cell cycle. 2011. Pharmacol Biochem Behav 100:98-108.

Taffe, M.A., R.W. Kotzebue, R.D. Crean, E.F. Crawford, S. Edwards, and C.D. Mandyam, Long-lasting reduction in hippocampal neurogenesis by alcohol consumption in adolescent nonhuman primates. Proc Natl Acad Sci U S A, 2010. Jun 15;107(24):11104-9.

Richardson, H.N., S.H. Chan, E.F. Crawford, Y.K. Lee, C.K. Funk, G.F. Koob, and C.D. Mandyam, Permanent impairment of birth and survival of cortical and hippocampal proliferating cells following excessive drinking during alcohol dependence. Neurobiol Dis, 2009. 36(1): p. 1-10.

Wee, S., C.D. Mandyam, D.M. Lekic, and G.F. Koob, Alpha 1-noradrenergic system role in increased motivation for cocaine intake in rats with prolonged access. Eur Neuropsychopharmacol, 2008. 18(4): p. 303-11.

Mandyam, C.D., S. Wee, E.F. Crawford, A.J. Eisch, H.N. Richardson, and G.F. Koob, Varied access to intravenous methamphetamine self-administration differentially alters adult hippocampal neurogenesis. Biol Psychiatry, 2008. 64(11): p. 958-65.

Mandyam, C.D., E.F. Crawford, A.J. Eisch, C.L. Rivier, and H.N. Richardson, Stress experienced in utero reduces sexual dichotomies in neurogenesis, microenvironment, and cell death in the adult rat hippocampus. Dev Neurobiol, 2008. 68(5): p. 575-89.

George, O., C.D. Mandyam, S. Wee, and G.F. Koob, Extended access to cocaine self-administration produces long-lasting prefrontal cortex-dependent working memory impairments. Neuropsychopharmacology, 2008. 33(10): p. 2474-82.

Arguello, A.A., G.C. Harburg, J.R. Schonborn, C.D. Mandyam, M. Yamaguchi, and A.J. Eisch, Time course of morphine's effects on adult hippocampal subgranular zone reveals preferential inhibition of cells in S phase of the cell cycle and a subpopulation of immature neurons. Neuroscience, 2008. 157(1): p. 70-9.

Mandyam, C.D., S. Wee, A.J. Eisch, H.N. Richardson, and G.F. Koob, Methamphetamine self-administration and voluntary exercise have opposing effects on medial prefrontal cortex gliogenesis. J Neurosci, 2007. 27(42): p. 11442-50.

Mandyam, C.D., G.C. Harburg, and A.J. Eisch, Determination of key aspects of precursor cell proliferation, cell cycle length and kinetics in the adult mouse subgranular zone. Neuroscience, 2007. 146(1): p. 108-22.

Lagace, D.C., M.C. Whitman, M.A. Noonan, J.L. Ables, N.A. DeCarolis, A.A. Arguello, M.H. Donovan, S.J. Fischer, L.A. Farnbauch, R.D. Beech, R.J. DiLeone, C.A. Greer, C.D. Mandyam, and A.J. Eisch, Dynamic contribution of nestin-expressing stem cells to adult neurogenesis. J Neurosci, 2007. 27(46): p. 12623-9.

Eisch, A.J. and C.D. Mandyam, Adult neurogenesis: can analysis of cell cycle proteins move us "Beyond BrdU"? Curr Pharm Biotechnol, 2007. 8(3): p. 147-65.

Bawa-Khalfe, T., G.F. Altememi, C.D. Mandyam, L.A. Schwarz, D.C. Eikenburg, and K.M. Standifer, The presence of beta2-adrenoceptors sensitizes alpha2A-adrenoceptors to desensitization after chronic epinephrine treatment. BMC Pharmacol, 2007. 7: p. 16.

Battiste, J., A.W. Helms, E.J. Kim, T.K. Savage, D.C. Lagace, C.D. Mandyam, A.J. Eisch, G. Miyoshi, and J.E. Johnson, Ascl1 defines sequentially generated lineage-restricted neuronal and oligodendrocyte precursor cells in the spinal cord. Development, 2007. 134(2): p. 285-93.

Richardson, H.N., E.P. Zorrilla, C.D. Mandyam, and C.L. Rivier, Exposure to repetitive versus varied stress during prenatal development generates two distinct anxiogenic and neuroendocrine profiles in adulthood. Endocrinology, 2006. 147(5): p. 2506-17.

Mandyam, C.D., R.D. Norris, and A.J. Eisch, Chronic morphine induces premature mitosis of proliferating cells in the adult mouse subgranular zone. Journal of Neuroscience Research, 2004. 76(6): p. 783-94.

Eisch, A.J. and C.D. Mandyam, Beyond BrdU: Basic and clinical implications for analysis of endogenous cell cycle proteins. Progress in stem cell research. Nova Science Publishers Inc, 2004.

Eisch, A.J. and C.D. Mandyam, Drug dependence and addiction, II: Adult neurogenesis and drug abuse. American Journal of Psychiatry, 2004. 161(3): p. 426.

Mandyam, C.D., D.R. Thakker, and K.M. Standifer, Mu-opioid-induced desensitization of opioid receptor-like 1 and mu-opioid receptors: differential intracellular signaling determines receptor sensitivity. J Pharmacol Exp Ther, 2003. 306(3): p. 965-72.

Mandyam, C.D., D.R. Thakker, J.L. Christensen, and K.M. Standifer, Orphanin FQ/nociceptin-mediated desensitization of opioid receptor-like 1 receptor and mu opioid receptors involves protein kinase C: a molecular mechanism for heterologous cross-talk. J Pharmacol Exp Ther, 2002. 302(2): p. 502-9.

Mathis, J.P., C.D. Mandyam, G.F. Altememi, G.W. Pasternak, and K.M. Standifer, Orphanin FQ/nociceptin and naloxone benzoylhydrazone activate distinct receptors in BE(2)-C human neuroblastoma cells. Neurosci Lett, 2001. 299(3): p. 173-6.

Mandyam, C.D., G.F. Altememi, and K.M. Standifer, beta-Funaltrexamine inactivates ORL1 receptors in BE(2)-C human neuroblastoma cells. Eur J Pharmacol, 2000. 402(1-2): p. R1-37.

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