Evaluating protein structure and function is of primary importance for understanding the basic biology of the cell and is a challenge in the context of the constantly expanding wealth of genomic information. more>>

We have established high-throughput approaches

Gallery of structures solved by JCSG

to evaluating structural and functional diversity of proteins to address this challenge part of a structural genomics effort with the Joint Center for Structural Genomics (JCSG). more>>

We apply these same tools to characterize the molecular basis of enzyme substrate specificity. more>>