Publications
Work @ Scripps
Hughes TS, Chalmers MJ, Novick S, Kuruvilla DS, Chang MR, Kamenecka TM, Rance M, Johnson BA, Burris TP, Griffin PR and Kojetin DJ. Ligand and receptor dynamics contribute to the mechanism of graded PPARγ agonism. Structure (2012) 20(1): 139-150 [PMID: 22244763]
Solt LA, Kojetin DJ, Burris TP. The REV-ERBs and RORs: molecular links between circadian rhythms and lipid homeostasis. Future Med Chem (2011) 3(5): 623-38. [PMID: 21526899]
Zhang J, Chalmers MJ, Stayrook KR, Burris LL, Wang Y, Busby SA, Pascal BD, Garcia-Ordonez RD, Bruning JB, Istrate MA, Kojetin DJ, Dodge JA, Burris TP and Griffin PR. DNA binding alters coactivator interaction surfaces of the intact VDR/RXR complex. Nat Struct Mol Biol (2011) 18(5) 556-63. [PMID: 21478866]
Kumar N, Kojetin D, Solt L, Kumar K, Nuhant P, Cameron M, Butler A, Roush W, Griffin PR, Burris TP. Identification of ML176 (SR3335): a Synthetic RORa Selective Inverse Agonist. ACS Chem Biol (2010) [PMID: 21090593]
Kojetin D, Wang Y, Kamenecka TM, Burris TP. Identification of SR8278, a Synthetic Antagonist of the Nuclear Heme Receptor REV-ERB. ACS Chem Biol (2011) 6(2): 131-4. [PMID: 21043485]
Kojetin DJ, Burris TP. A Role for Rev-erbα Ligands in Regulation of Adipogenesis. Curr Pharm Des(2011) 17(4): 320-4. [PMID: 21375499]
Crumbley C, Wang Y, Kojetin DJ, Burris TP. Characterization of the core mammalian clock component, NPAS2, as a REV-ERB{alpha}/ROR{alpha} target gene. J Biol Chem (2010) 285(46): 35386-92. [PMID: 20817722) [PMC Journal - In Process]
Work Before Scripps
Doerdelmann T, Kojetin DJ, Baird-Titus JM, Solt LA, Burris TP and Rance M. Structural and Biophysical Insights into the Ligand Free Pitx2 Homeodomain and a Ring Dermoid of the Cornea Inducing Homeodomain Mutant. Biochemistry (2012) 51(2): 665-76. [PMID: 22224469]
Doerdelmann T, Kojetin DJ, Baird-Titus JM, Rance M. 1H, 13C and 15N chemical shift assignments for the human Pitx2 homeodomain in complex with a 22-base hairpin DNA. Biomol NMR Assign (2011) Aug 5 (Epub ahead of print). [PMID: 21818549]
Refaei MA, Combs A, Kojetin D, Cavanagh J, Rance M, Sapitro J, Tsang P. Observing Selected Domains in Multi-Domain Proteins via Sortase-Mediated Ligation and NMR Spectroscopy. J Biomol NMR (2011) 49(1): 3-7. [PMID: 21188472]
Doerdelmann T, Kojetin DJ, Baird-Titus J, Rance M. 1H, 13C and 15N chemical shift assignments for the human Pitx2 homeodomain and a R24H homeodomain mutant. J Biomol NMR Assign (2011) 5(1): 105-7. [PMID: 21052876]
Kojetin DJ*, McLaughlin PD*, Thompson R, Dubnau D, Prepiak P, Rance M, Cavanagh J. Structural and motional contributions of the Bacillus subtilis ClpC N-domain in adaptor protein interactions. J Mol Biol (2009) 387(3): 639-52. [PMID: 19361434]
Sullivan D*, Bobay BG*, Kojetin DJ*, Thompson R, Rance M, Strauch MA, Cavanagh J. Insights into the nature of DNA-binding of AbrB-like transcription factors. Structure (2008) 16(11): 1702-13. [PMID: 19000822]
Kojetin DJ, Burris TP, Jensen EV, Khan SA. Implications of the binding of tamoxifen to the coactivator recognition site of the estrogen receptor. Endocr Relat Cancer (2008) 15(4): 851-70. [PMID: 18755852]
Kojetin DJ*, McLaughlin PD*, Thompson R, Venters RA, Rance M, Cavanagh J. NMR assignment of the N-terminal repeat domain of Bacillus subtilis ClpC. Biomol NMR Assn (2007) 1(2): 163-5. [PMID: 19636855]
Kojetin DJ, Sullivan D, Thompson R, Cavanagh J. Classification of response regulators based on their surface properties. Meth Enzymol (2007) 422: 141-69. [PMID: 17628138]
Kojetin DJ*, Venters RA*, Kordys DR, Thompson R, Kumar R, Cavanagh J. Structure, binding interface and hydrophobic transitions of Ca2+-loaded calbindin-D28K. Nat Struct Mol Biol (2006) 13(7): 641-7. [PMID: 16799559]
Kojetin DJ, Thompson RJ, Benson LM, Naylor S, Waterman J, Davies KG, Opperman CH, Stephenson K, Hoch JA, Cavanagh J. Structural analysis of divalent metals binding to the Bacillus subtilis response regulator Spo0F: the possibility for in vitro metalloregulation in the initiation of sporulation. Biometals (2005) 18(5): 449-66. [PMID: 16333746]
Venters RA, Coggins BE, Kojetin D, Cavanagh J, Zhou P. (4,2)D Projection—reconstruction experiments for protein backbone assignment: application to human carbonic anhydrase II and calbindin D28K. J Am Chem Soc (2005) 127(24): 8785-95. [PMID: 15954785]
Kojetin DJ, Thompson RT, Cavanagh J. Sub-classification of response regulators using the surface characteristics of their receiver domains. FEBS Lett (2003) 554(3): 231-6. [PMID: 14623071]Ulrich D*,
Kojetin DJ*, Bassler BL, Cavanagh J, Loria JP. Solution structure and dynamics of LuxU from Vibrio harveyi, a phosphotransferase protein involved in bacterial quorum sensing. J Mol Biol (2005) 347(2): 297-307. [PMID: 15740742]
Lutz W, Frank EM, Craig TA, Thompson R, Venters RA, Kojetin DJ, Cavanagh J, Kumar R. Calbindin D28K Interacts with Ran-binding protein M: identification of interacting domains by NMR spectroscopy. Biochem Biophys Res Commun (2003) 303(4): 1186-92. [PMID: 12684061]
Helton TD, Kojetin DJ, Cavanagh J, and Horne WA. Alternative splicing of a beta4 subunit proline-rich motif regulates voltage-dependent gating and toxin block of Cav2.1 Ca2+ channels. J Neurosci(2002) 22(21): 9331-9. [PMID: 12417658]
Phillips CL, Arend LJ, Filson AJ, Kojetin DJ, Clendenon JL, Fang S, Dunn KW. Three-dimensional imaging of embryonic mouse kidney by two-photon microscopy. Am J Pathol (2001) 158(1): 49-55. [PMID: 11141478]
