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The Kodadek Lab

Publications

2017

Koesema E., Kodadek T. (2017) Global analysis of gene expression mediated by OX1 orexin receptor signaling in a hypothalamic cell line. Plos One. 12(11):e0188082.

Wu Hao, An H, Mo S, Kodadek T. (2017) Asymmetric Synthesis of Vinylogous β-Amino Acids and Their Incorporation Into Mixed Backbone Oligomers. Org Biomol Chem. 15(15):3255-3264.

Trader DJ, Simanski S, Dickson P, Kodadek T. (2017) Establishment of a suite of assays that support the discovery of proteasome stimulators. Biochim Biophys Acta. 1861(4):892-899.

Mendes KR, Malone ML, Ndungu JM, Suponitsky-Kroyter I, Cavett VJ, McEnaney PJ, MacConnell AB, Doran TM, Ronacher K, Stanley K, Utset O, Walzl G, Paegel BM, Kodadek T. (2017) High-throughput Identification of DNA-Encoded IgG Ligands that Distinguish Active and Latent Mycobacterium tuberculosis Infections. ACS Chem Biol. 12(1):234-243.

2016

Wu H, Mousseau G, Mediouni S, Valente ST, Kodadek T. (2016) Cell-Permeable Peptides Containing Cycloalanine Residues. Angew Chem Int Ed Engl. 55(41):12637-42.

Wu SY, Nin DS, Lee AY, Simanski S, Kodadek T, Chiang CM. (2016) BRD4 Phosphorylation Regulates HPV E2-Mediated Viral Transcription, Origin Replication, and Cellular MMP-9 Expression. Cell Rep. 16(6):1733-48.

Doran TM, Morimoto J, Simanski S, Koesema EJ, Clark LF, Pels K, Stoops SL, Pugliese A, Skyler JS, Kodadek T. (2016) Discovery of Phosphorylated Peripherin as a Major Humoral Autoantigen in Type 1 Diabetes Mellitus. Cell Chem. Biol. 23(5):618-28.

Gearhart TL, Montelaro RC, Schurdak ME, Pilcher CD, Rinaldo CR, Kodadek T, Park Y, Islam K, Yurko R, Marques ET Jr, Burke DS. (2016) Selection of a potential diagnostic biomarker for HIV infection from a random library of non-biological synthetic peptoid oligomers. J Immunol Methods. 435:85-9.

Sarma BK, Liu X, Kodadek T. (2016) Identification of selective covalent inhibitors of platelet activating factor acetylhydrolase 1B2 from the screening of an oxadiazolone-capped peptoid-azapeptoid hybrid library. Bioorg. Med Chem 24(17):3953-63.

Doran TM, Sarkar M, Kodadek T. (2016) Chemical Tools to Monitor and Manipulate Adaptive Immune Responses. J Am Chem Soc. 138(19):6076-94.

Clark LF, Kodadek T. (2016) The Immune System and Neuroinflammation as Potential Sources of Blood-Based Biomarkers for Alzheimer's Disease, Parkinson's Disease, and Huntington's Disease. ACS Chem Neurosci. 7(5):520-7.

Kodadek T, McEnaney PJ. (2016) Towards vast libraries of scaffold-diverse, conformationally constrained oligomers. Chem Commun (Camb.) 52(36):6038-59.

Sarkar M, Liu Y, Qi J, Peng H, Morimoto J, Rader C, Chiorazzi N, Kodadek T. (2016) Targeting Stereotyped B Cell Receptors from Chronic Lymphocytic Leukemia Patients with Synthetic Antigen Surrogates. J Biol Chem. 291(14):7558-70.

2015

Clark LF, Kodadek T. (2015) And then there were two. Elife. Dec 30;4.

Doran TM, Morimoto J, Simanski S, McEnaney PJ, Kodadek T. (2015) Reliable diagnosis of murine type 1 diabetes using a panel of autoantigens and "antigen surrogates" mounted onto a liquid array. Mol Biosyst. 11(11):3156-63.

Mendes K, Ndungu JM, Clark LF, Kodadek T. (2015) Optimization of the Magnetic Recovery of Hits from One-Bead-One-Compound Library Screens. ACS Comb Sci. 17(9):506-17.

Li X, Patterson JT, Sarkar M, Pedzisa L, Kodadek T, Roush WR, Rader C. (2015) Site-Specific Dual Antibody Conjugation via Engineered Cysteine and Selenocysteine Residues. Bioconjug Chem. 26(11):2243-8.

Doran TM, Gao Y, Simanski S, McEnaney P, Kodadek T. (2015) High affinity binding of conformationally constrained synthetic oligomers to an antigen-specific antibody: Discovery of a diagnostically useful synthetic ligand for murine Type 1 diabetes autoantibodies. Bioorg Med Chem Lett. 25(21):4910-7.

Morimoto J, Kodadek T. (2015) Synthesis of a large library of macrocyclic peptides containing multiple and diverse N-alkylated residues. Mol Biosyst. 11(10):2770-9.

Trader DJ, Simanski S, Kodadek T. (2015) A reversible and highly selective inhibitor of the proteasomal ubiquitin receptor Rpn13 is toxic to multiple myeloma cells. J. Amer. Chem. Soc. 137(19):6312-9.

Pels K, Kodadek T. (2015) Solid-phase synthesis of diverse peptide tertiary amides by reductive amination. ACS Comb Sci17(3):152-5.

Gao, Y. and Kodadek, T. (2015) Direct comparison of linear and macrocyclic compounds as a source of protein ligands. ACS Comb. Sci. 17(3):190-5.

Cravatt BF, Kodadek T. (2015) Editorial overview: Omics: Methods to monitor and manipulate biological systems: recent advances in "omics." Curr Opin Chem Biol.

Doran, T.M., Simanski, S. and Kodadek, T. (2015) Discovery of native autoantigens via antigen surrogate technology: Application to type 1 diabetes. ACS Chem. Biol. 10(2):401-12.

Sarkar, M., Liu, Y., Morimoto, J., Peng, H., Aquino, C., Rader, C., Chiorazzi, N. and Kodadek, T. (2015) Recognition of antigen-specific B cell receptors from chronic lymphocytic leukemia patients by synthetic antigen surrogates. Chem & Biol. 21, 21(12):1670-9.

Gao, Y., Amar, S., Pahwa, S., Fields, G. and Kodadek, T. (2015) Rapid lead discovery through iterative screening of one bead one compound libraries. ACS Comb. Sci. 17(1):49-59.

2014

Sarma BK, Liu X, Wu H, Gao Y, Kodadek T. (2014) Solid phase synthesis of 1,3,4-oxadiazin-5 (6R)-one and 1,3,4-oxadiazol-2-one scaffolds from acyl hydrazides. Org Biomol Chem. 12, 59-63.

Morimoto J, Sarkar M, Kenrick S, Kodadek T. (2014) Dextran as a Generally Applicable Multivalent Scaffold for Improving Immunoglobulin-Binding Affinities of Peptide and Peptidomimetic Ligands. Bioconjug Chem. 25, 1479-1491.

Kodadek T. (2014) Chemical tools to monitor and manipulate the adaptive immune system. Chem Biol. 21(9):1066-74.

Suwal S, Kodadek T. (2014) Solid-phase synthesis of peptoid-like oligomers containing diverse diketopiperazine units. Org Biomol Chem. 12(31):5831-4.

Doran TM, Gao Y, Mendes K, Dean S, Simanski S, Kodadek T. (2014) Utility of redundant combinatorial libraries in distinguishing high and low quality screening hits. ACS Comb Sci. 16(6):259-70.

Vanderstichele H, Kodadek T. (2014) Roadblocks for integration of novel biomarker concepts into clinical routine: the peptoid approach.  Alzheimers Res Ther. 6(2):23.

Gao Y, Kodadek T. (2014) Split-and-pool synthesis and characterization of peptide tertiary amide library. J Vis Exp. (88):e51299.

Quan J, Lakhanpal A, Reddy MM, Zaman S, Li QZ, German DC, Olsen NJ, Kodadek T, Karp DR. (2014) Discovery of biomarkers for systemic lupus erythematosus using a library of synthetic autoantigen surrogates. J Immunol Methods. 402(1-2):23-34.

Doran TM, Kodadek T. (2014) A liquid array platform for the multiplexed analysis of synthetic molecule-protein interactions. ACS Chem Biol. 9(2):339-46.

2013

Kodadek T. (2013) A jack of all trades to combat drug-resistant Gram-negative bacteria. Chem Biol. 20(10):1202-3.

Rzuczek SG, Gao Y, Tang ZZ, Thornton CA, Kodadek T, Disney MD. (2013) Features of modularly assembled compounds that impart bioactivity against an RNA target.  ACS Chem Biol. 8(10):2312-21

Clark, L.F. and Kodadek, T. (2013) Advances in blood-based protein biomarkers for Alzheimer’s disease. Alzheimer’s Research & Therapy 5, 18-25.

Sarkar, M., Pascal, B.D., Steckler, C., Micalizio, G.C., Kodadek, T. and Chalmers, M.J. (2013) Decoding split and pool combinatorial libraries with electron transfer dissociation tandem mass spectrometry. J. Amer. Soc. Mass Spec. 24, 1026-1036.

Gao, Y. and Kodadek, T. (2013) Synthesis and Screening of Stereochemically Diverse Combinatorial Libraries of Conformationally Restrained Peptide Tertiary Amides. Chem. & Biol. 20, 360-369.

Raveendra, B., Hao, W., Baccala, R., Reddy, M.M., Schilke, J., Bennett, J.L., Theofilopoulos, A.N. and Kodadek, T. (2013) Discovery of peptoid ligands for anti-Aquaporin 4 antibodies. Chem. & Biol. 20, 351-359

Suwal, S. and Kodadek, T. (2013) Synthesis of Libraries of Peptidomimetic Compounds Containing A 2-Oxopiperazine Unit In The Main Chain. Org. Biomol. Chem. 11, 2088 – 2092.

2012

Sarma, B.K. and Kodadek, T. (2012) Sub-Monomer Synthesis of A Hybrid Peptoid-Azapeptoid Library. ACS Comb. Sci. 14, 558-564.

Liu, X. Dix, M., Speers, A.E., Bachovchin, D.A., Zuhl, A.M., Cravatt, B.F. and Kodadek, T. (2012) Rapid Development of a Potent Photo-Triggered Inhibitor of the Serine Hydrolase RBBP9. ChemBioChem. 13, 2082-2093.

Simpson, L. and Kodadek, T. (2012) A cleavable scaffold strategy for the synthesis of one-bead one-compound cyclic peptoid libraries that can be sequenced by tandem mass spectrometry. Tet.Lett. 53, 2341-2344.

Udugamasooriya DG, Kodadek T. (2012) On-Bead Two-Color (OBTC) Cell Screen for Direct Identification of Highly Selective Cell Surface Receptor Ligands. Curr Protoc Chem Biol. 4:35-48.

Aditya, A. and Kodadek, T. (2012) Incorporation of heterocycles into the backbone of peptoids to generate diverse peptoid-inspired one bead one compound libraries. ACS Comb. Sci. 14, 164-169.

2011

Aquino, C., Sarkar, M., Chalmers, M.J., Mendes, K., Kodadek, T. and Micalizio, G. (2011) A Biomimetic polyketide-inspired approach to small molecule ligand discovery. Nature Chemistry 4, 99-104.

Chen X, Wu J, Luo Y, Liang X, Supnet C, Kim MW, Lotz GP, Yang G, Muchowski PJ, Kodadek T, Bezprozvanny I. (2014) Expanded polyglutamine-binding peptoid as a novel therapeutic agent for treatment of Huntington's disease. Chem Biol. 18(9):1113-25.

Mendes, K. and Kodadek, T. (2011) PDZ dimerization brings proteins together. Chem. & Biol. 18, 1071-1072.

Sarma, B.K., Yousufuddin, M. and Kodadek, T. (2011) Acyl hydrazides as peptoid sub-monomers. Chem. Comm 47, 10590-10592.

Cai, D., Lee, A.Y., Chiang, C.-M. and Kodadek, T. (2011) Peptoid ligands that bind selectively to phosphoproteins. Bioorg. Med. Chem. Lett. 21, 4960-4964.

Kodadek, T. (2011) The rise, fall and reinvention of combinatorial chemistry. Chem. Comm. 47, 9757-9763.

Reddy, M.M., Wilson, R., Wilson, J., Connell, S., Gocke, A., Hynan, L., German, D. and Kodadek, T. (2011) Identification of candidate IgG biomarkers for Alzheimer’s disease via combinatorial library screening. Cell 144, 132-142.

2010

Kodadek T, Cai D, (2010) Chemistry and biology of orexin signaling. Mol Biosyst. 6(8):1366-75

Kodadek T. (2010) Synthetic receptors with antibody-like binding affinities. Curr Opin Chem Biol. 14(6):713-20.

Kodadek T. (2010) Development of antibody surrogates for the treatment of cancers and autoimmune disease. Curr Opin Chem Biol. 14(6):721-7.

Astle, JM, Simpson LS, Huang Y. Reddy, MM, Wilson, R, Connell S, Wilson J, Kodadek T., (2010)  Seamless bead to microarray screening:  rapid identification of teh highest affinity protein ligands from large combinatorial librairies.  Chem Bio 17(1):38-45.

Lee, J., Reddy, M.M. and Kodadek, T. (2010)  Discovery of an orexin receptor positive potentiator.  Chem Sci. 1, 48-54.

Lee, J., Udugamasooriya, D.G., Lim, H.-S. and Kodadek, T. (2010) Potent and selective photo-inactivation of proteins with peptoid-ruthenium conjugates. Nature Chem. Biol. 6, 258-260.

Kodadek, T. (2010) Rethinking screening. Nature Chem. Biol. 6, 162-165.

2009

Gocke, A. R., Udugamasooriya, D.G., Archer, C.T., Lee, J. and Kodadek, T. (2009) Isolation of antagonists of antigen-specific autoimmune T cell proliferation. Chem. & Biol. 16, 1133-1139.

Chan, Y.-C., Wu, S.-Y., Lim, H.-S., Chiang, C.-M. and Kodadek, T. (2009) Non-proteolytic regulation of p53-mediated transcription through destabilization of the activator-promoter complex by the proteasomal ATPases. J. Biol. Chem. 284, In press.

Qi, X., Astle, J. and Kodadek, T. (2009) Rapid identification of orexin receptor ligands using cell-based screening accelerated with magnetic beads. Molecular BioSystems 5, In press.

Liu, B. and Kodadek, T. (2009) Investigating the Cellular Permeability of DNA-binding Pyrrole-Imidazole Polyamides. J. Med. Chem. 52, 4604-4612.

Lim, H.-S., Reddy, M.M., Xiao, X., Wilson, J., Wilson, R., Connell, S. and Kodadek, T. (2009) Rapid identification of improved protein ligands using peptoid microarrays. Bioorganic Med. Chem. Lett. 19, 3866-3869.

Zuckermann, R.N. and Kodadek, T. (2009) Peptoids as potential therapeutics. Curr. Opin. Mol. Therapeutics. 11, 299-307.

Simpson, L.S., Burdine, L., Dutta, A.K., Feranchak, A.P. and Kodadek, T. (2009) Selective Toxin Sequestrants for the Treatment of Bacterial Infections. J. Amer. Chem. Soc. 131, 5760-5762.

Friedberg, E.C. and Kodadek, T. (2009) Nucleic Acids: Chemical Damage. Volume 3, 467-480 in Wiley Encyclopedia of Chemical Biology. John Wiley & Sons, Inc., Hoboken, N.J.

2008

Archer, C.T., Burdine, L., Liu, B., Ferdous, A., Johnston, S.A. and Kodadek, T. (2008) Physical and functional interaction of mono-ubiquitylated transactivators with the proteasome. J. Biol. Chem. 283, 21789-21798.

Kwon, Y.-U. and Kodadek, T. (2008) Encoded combinatorial libraries for the construction of cyclic peptoid microarrays. Chem. Comm. 5704-5706.

Udugamasooriya, D.G., Dunham, G., Ritchie, C., Brekken, R.A. and Kodadek, T. (2008) The pharmacophore of a peptoid VEGF Receptor antagonist includes both side chain and main chain residues. Bioorg, Med. Chem. Lett. 18, 5892-5894.

Kodadek, T. (2008) Rise of the machines: Bruce Alberts and the biochemistry of multi-protein complexes. Mol. BioSystems. 4, 1043-1045.

Ferdous, A., O'Neal, M., Nalley, K., Sikder, D., Kodadek, T. and Johnston, S.A. (2008) Phosphorylation of the Gal4 DNA-binding domain is essential for activator mono-ubiquitylation and effeficient promoter occupancy. Mol. BioSystems. 4, 1116-1125.

Archer, C.T., Burdine, L., Liu, B., Ferdous, A., Johnston, S.A. and Kodadek, T. (2008) Physical and functional interaction of mono-ubiquitylated transactivators with the proteasome. J. Biol. Chem. 283, 21789-21798.

Astle, J.M., Udugamasooriya, D.G., Smallshaw, J.E. and Kodadek, T. (2008) A VEGFR2 antagonist and other peptoids evade immune recognition. Intl. J. Peptide Res. & Therapeutics. 14, 223-227.

Kodadek, T. (2008) Molecular cloaking devices. Nature. 453, 861-862.

Tan, N.C., Yu, P., Kwon, Y.-U. and Kodadek, T. (2008) High-throughput evaluation of relative cell permeability between peptoids and peptides. Bioorg. Med. Chem. 16, 5853-5861.

Kodadek, T. (2008) Proteomes take the electrophilic bait. Nature Chem. Biol. 4, 387-388.

Udugamasooriya, D.G., Ritchie, C., Brekken, R.A. and Kodadek, T. (2008) A Peptoid Antagonist of VEGF Receptor 2 Recognizes A Hotspot In the Extracellular Domain Distinct From The Hormone-Binding Site. Bioorg. & Med. Chem. 16, 6338-6343.

Hanaoka, K., Lubag, A.J.M., Castillo-Muzquiz, A., Kodadek, T. and Sherry, A.D. (2008) The detection limit of a Gd3+-based T1 agent is substantially reduced when targeted to a protein microdomain. Mag. Res. Imaging. 26, 608-617.

Udugamasooriya, D.G., Dineen, S.P., Brekken, R.A. and Kodadek, T. (2008) A peptoid antibody surrogate that antagonizes VEGF Receptor 2 activity. J. Amer. Chem. Soc. 130, 5744-52.

Archer, C.T., Delahodde, A., Gonzalez, F., Johnston, S.A. and Kodadek, T. (2008) Activation domain-dependent mono-ubiquitylation of Gal4 protein is essential for promoter binding in vivo. J. Biol. Chem. 283, 12614-12623.

Shores, K.S., Udugamasooriya, D.G., Kodadek, T. and Knapp, D.R. (2008) Use of peptide analog diversity library beads for increased depth of proteomic analysis: Application to cerebrospinal fluid. J. Proteome Res. 7, 1922-1931.

Marthandan, N., Klyza, S., Li, S., Kodadek, T. and Garner, H.R. (2008) Construction and evaluation of an automated light directed protein-detecting microarray synthesizer. IEEE Transactions in NanoBioscience. 7, 20-27.

Lim, H.-S., Archer, C.T., Kim, Y.-C., Hutchens, T. and Kodadek, T. (2008) Rapid identification of the pharmacophore in a peptoid inhibitor of the proteasome regulatory particle. Chem. Comm. 1064-1066.

Lee, J., Yu, P., Xiao, X. and Kodadek, T. (2008) A General System for Evaluating the Efficiency of Chromophore-Assisted Light Inactivation (CALI) of Proteins Reveals Ru(II) tris-bipyridyl As An Unusually Efficient Warhead. Molecular BioSystems. 4, 59-65.

2007

Astle, J. Ferguson, JT. German, JB. Harrigan, GG. Kelleher, NL. Kodadek, T. Parks, BA. Roth, MJ. Singletary, KW. Wenger, CD. Mahady, G.B. (2007) Characterization of proteomic and metabolomic responses to dietary factors and supplements. J. of Nutrition. 137, 2787-2793.

Yu, P. and Kodadek, T. (2007) Dynamics of the Hypoxia-Inducible Factor-1-VEGF promoter complex. J. Biol. Chem. 282, 35035 – 35045.

Lim, H.-S., Cai, D. and Kodadek, T. (2007) Chemical cross-linking reveals Sug2/Rpt4 as the molecular target of a peptoid inhibitor of the 19S proteasome regulatory particle. J. Amer. Chem. Soc. 129, 12936-12937.

Sikder, D. and Kodadek, T. (2007) The neurohormone orexin stimulates hypoxia-inducible factor-1 activity. Genes & Devel. 21, 2995-3005

Liu, B., Archer, C.T., Burdine, L., Gillette, T.G. and Kodadek, T. (2007) Label transfer chemistry for the characterization of protein-protein interactions. J. Amer. Chem. Soc. 129, 12348-12349.

Kwon, Y.-U. and Kodadek, T. (2007) Quantitative comparison of the relative cell permeability of cyclic and linear peptides. Chem. & Biol. 14, 671-677.

Lim, H.-Y., Archer, C.T. and Kodadek, T. (2007) Identification of a peptoid inhibitor of the proteasome 19S regulatory particle. J. Amer. Chem. Soc. 129, 7750-7751.

Xiao, X., Yu, P., Lim, H.-Y., Sikder, S. and Kodadek, T. (2007) Design and synthesis of a cell permeable transcription factor mimic. J. Comb. Chem. 9, 592-600.

Xiao, X., Yu, P., Lim, H.-S., Sikder, D. and Kodadek, T. (2007) A cell permeable transcription factor mimic. Angew. Chem. Intl. Ed. 46, 2865-2868.

Yu, P. and Kodadek, T. (2007) A convenient, high-throughput strategy for measuring the relative cell permeability of synthetic compounds. Nature Protocols. 2, 23-30.

Kwon, Y.-U. and Kodadek, T. (2007) Quantitative evaluation of the relative cell permeability of peptoids and peptides. J. Amer. Chem. Soc. 129, 1508-1509.

Ferdous, A., Sikder, D., Gillette, T., Nalley, K., Kodadek, T. and Johnston, S.A. (2007) The Role of the Proteasomal ATPases and Activator Mono-Ubiquitylation in Regulating Gal4 Binding to Promoters. Genes & Dev. 21, 112-123.

2006

Liu, B., Burdine, L. and Kodadek, T. (2006) Chemistry of periodate-mediated cross-linking of 3,4-dihydroxyphenlalanine (DOPA)-containing molecules to proteins. J. Amer. Chem. Soc. 128, 15228-15235.

Page, T., Sikder, D. Yang, L. Pluta, L., Wolfinger, R.D., Kodadek, T. and Thomas, R.S. (2006) Genome-wide analysis of human HSF1 signaling reveals a transcriptional program linked to cellular adaptation and survival. Molecular BioSystems. 2, 627-639.

Kodadek, T., Sikder, D. and Nalley, K. (2006) Keeping transcriptional activators under control. Cell. 127, 261-264.

Sikder, D., Johnston, S.A. and Kodadek, T. (2006) Widespread, but non-identical, association of proteasomal 19S and 20S proteins with yeast chromatin. J. Biol. Chem. 281, 27346-27355.

Nalley, K., Johnston, S.A. and Kodadek, T. (2006) Proteolytic turnover of Gal4 is not required for function in vivo. Nature. 442, 1054-1057.

Alluri, P., Liu, B., Yu, P., Xiao, X. and Kodadek, T. (2006) isolation and chearacterization of coactivator-binding peptoids from a combinatorial library. Molecular Biosystems. 2, 568-579.

Sulahian, R., Sikder, D., Johnston, S.A. and Kodadek, T. (2006) The Proteasomal ATPase Complex Is Required For Stressed-Induced Trasncription in Yeast. Nucl. Acids Res. 34, 1351-1357.

Sikder, K. and Kodadek, T. (2006) Optimized protocols for the isolation of specific protein-binding peptides or peptoids from combinatorial libraries displayed on beads. Molecular BioSystems. 2, 25-35.

2005

Archer, C., Burdine, L. and Kodadek, T. (2005) Identification of Gal4 transactivation domain binding proteins in the 26S proteasome by perioddate-triggered cross-linking. Molecular BioSystems. 1, 366-372.

Liu, B., Yu, P., Alluri, P.G. and Kodadek, T. (2005) Simple reporter gene-based assays for hairpin polyamide conjugate permeability and DNA-binding activity in living cells. Molecular BioSystems. 1, 307-317.

Reddy, M.M. and Kodadek, T. (2005) Protein 'fingerprinting' in complex mixtures using peptoid microarrays.  Proc. Natl. Acad. Sci. USA 102, 12672-12677.

Liu, B., Alluri, P., Yu, P. and Kodadek, T. (2005) A KIX-binding peptoid functions as a transactivation domain in mammalian cells.  J. Amer. Chem. Soc. 127, 8254-8255.

Yu, P., Liu, B. and Kodadek, T. (2005) A high-throughput assay for assessing the cell permeability of combinatorial libraries. Nature Biotechnol. 23, 746-751.

Li, S., Marthandan, N., Bowerman, D., Garner, H.R. and Kodadek, T. (2005) Photolithographic synthesis of cyclic peptide arrays using a differential deprotection strategy. Chem. Comm. (5): 581-583.

2004

Gillette, T., Gonzalez, F.G., Delahodde, A., Johnston, S.A. and Kodadek, T. (2004) Physical and Functional Association of RNA Polymerase II and the Proteasome. Proc. Natl. Acad. Sci. USA 101, 5904-5909.

2002

Gonzalez, F., Delahoude, A., Kodadek, T. and Johnston, S.A. (2002) A sub-complex of the 19S proteasome regulatory complex is recruited to an activated promoter. Science. 296, 548-550.

2001

Ferdous, A., Gonzalez, F., Sun, L., Kodadek, T. and Johnston, S.A. (2001) The 19S regulatory particle of the proteasome is required for efficient transcription elongation by RNA polymerase II. Mol. Cell. 7, 981-991.