The Kodadek Lab

Thomas Kodadek, Ph.D.

Born
March 11, 1959, Chicago, IL

Current Position
Professor of Chemisry and Cancer Biology
The Scripps Research Institute, Scripps Florida
130 Scripps Way, #3A2
Jupiter, FL 33458

Previous Positions
Director, UT-Southwestern Division of Translational Research (2005-2009). Professor of Internal Medicine and Molecular Biology (1998-Present) University of Texas Southwestern Medical Center.

Professor of Chemistry and Biochemistry, University of Texas at Austin (1997-1998) Associate Professor (1993-1997), Assistant Professor (1987-1992).

Education
B.S.(Chemistry) University of Miami (FL)
Ph.D. (Organic Chemistry) Stanford University (Advisors: James Collman, John Brauman)
Post-doctoral (Biochemistry) UCSF (Advisor: Bruce Alberts)

Awards
Jane Coffin Childs Postdoctoral Fellow (1985-1987)
American Cancer Society Junior Faculty Research Award (1989-1991)
Fellow of the AAAS (elected 1999)
NIH Director's Pioneer Award (2006-2011).
Outstanding Teacher, Medical School (MS1) Biochemistry (2007)

Professional Activities and Services
Founding Chief of the Editorial Board Molecular BioSystems, Royal Society of Chemistry (1/04-12/09)
Editorial Board (1/98-Present): Chemistry & Biology
Associate Editor (6/99-5/03): Chemistry & Biology
Editorial Board (1/97-7/01): Chemtracts-Organic Chemistry
Co-Editor of Jan. 2000, Feb. 2005 Issues of Current Opinion In Chemical Biology
Vice Chair (2002) and Chair (2004), Gordon Conference Chemistry and Biology of Peptides
Member (2000-2004) and Chair (2002-2004) of the NIH Bioorganic and Natural Products (BNP) Study Section.
Member, Nucleic Acids Study Section, American Cancer Society (1995-98).
Member, DOE special study section for materials science research (1994).
Member of the American Chemical Society, AAAS, Royal Society of Chemistry.
Steering Committee Member, NIH Chemistry Assistant Professor Mentoring Workshops
Member, Scientific Advisory Board of Stratagene Inc., La Jolla, CA
Member, Scientific Advisory Board, Receptors, LLC, Chaska, MN
Member, Scientific Advisory Board of Sigma-Aldrich, Stl. Louis, MO.
Member, Scientific Advisory Board, Opko Health Inc, Miami, FL.
Co-Chair, NHLBI Committee for Strategic Planning in Emerging Technologies (2006)
Board Member, U.S. HUPO Coordinating Committee (2007)
Member, NIH committee on the Future of the Roadmap (2006)
Member, Special Study Section for NIH Director's Innovator Awards (2007-9)

Invited Lectures

1	National Institute of Environmental Health Sciences (NIEHS) Chapel Hill, NC "In vitro studies of phage T4 homologous recombination" October, 1986.
2	FASEB Conference on Genomic Rearrangements, Copper Mountain, CO "The enzymology of genetic recombination" June, 1987.
3	University of North Carolina, School of Medicine, Chapel Hill, NC "The enzymology of genetic recombination" February, 1988.
4	Cold Spring Harbor Laboratories, Cold Spring Harbor, NY "Characterization of accessory factors for homologous recombination" September, 1988.
5	Baylor College of Medicine, Houston, TX "The enzymology of homologous recombination" May, 1989.
6	Harvard Medical School, Boston, MA "The enzymology of genetic recombination" October, 1989.
7	MIT, Cambridge, MA "The enzymology of genetic recombination" October, 1989.
8	University of Texas at Arlington, Arlington, TX "Molecular engineering of novel catalytic systems: Applications in chemistry and biochemistry" December, 1989.
9	NSF Workshop on Asymmetric Synthesis, Pingree Park, CO "Novel catalytic chemistry of metalloporphyrins" July, 1990.
10	Alcon Laboratories, Fort Worth, TX "How to 'fine tune' the activity of natural and artificial enzymes" February, 1991.
11	Trinity University, San Antonio, TX "How to 'fine tune' the activity of natural and artificial enzymes" February, 1991.
12	Texas A&M University, College Station, TX "Controlling catalyst activty: A central problem in chemistry and biology" March, 1991.
13	The University of Texas Forum on Organic Chemistry and Biochemistry, Austin, TX "Multiple roles for DNA helicases in homologous strand exchange" May, 1991.
14	FASEB Conference on Genetic Recombination, Sax River, VT "Multiple roles for DNA helicases in homologous strand exchange", July, 1991.
15	American Society for Microbiology Annual Meeting, Austin, TX "The enzymology of bacteriophage T4 homologous recombination" October, 1991.
16	American Chemical Society, Southwest Regional Meeting, San Antonio, TX "Novel catalytic chemistry of metalloporphyrins" October, 1991.
17	Lost Pines Conference on Molecular Biology, Smithville, TX-Chair of Structural Biology Session, October, 1991.
18	University of Wisconsin, Madison, WI "Controlling catalyst selectivity: A central problem in chemistry and biology", October, 1991.
19	University of Wisconsin (Dept. of Biochemistry), Madison, WI "The enzymology of homologous recombination", October, 1991.
20	University of Kansas (Dept. of Medicinal Chemistry) - Eli Lilly Lecturer, Lawrence, KA "Controlling catalyst selectivity: A central problem in chemistry and biology" October, 1991.
21	University of Washington, Seattle, WA "Controlling catalyst selectivity: A central problem in chemistry and biology" November, 1991.
22	University of Oregon, Eugene OR "Novel catalytic chemistry of metalloporphyrins" November, 1991.
23	University of Oregon (Molecular Biology Institute), Eugene, OR "The enzymology of homologous recombination" November, 1991.
24	Stanford University, Stanford, CA "Controlling catalyst selectivity: A central problem in chemistry and biology" November, 1991.
25	Stanford University Medical School, Stanford, CA "The enzymology of homologous recombination" November, 1991.
26	24th Annual Symposium on Oxidation Chemistry, Hiroshima, Japan "Novel catalytic chemistry of metalloporphyins" November, 1991.
27	Teijin Institute for Biomedical Research, Tokyo, Japan "Novel catalytic chemistry of metalloporphyins" November, 1991.
28	Tokyo University, Tokyo, Japan "Novel catalytic chemistry of metalloporphyins" November, 1991.
29	Kyoto University, Kyoto, Japan "Novel catalytic chemistry of metalloporphyins" November, 1991.
30	Texas A&M University (Department of Biochemistry), College Station, TX "The enzymology of homologous recombination" January, 1992.
31	University of Houston, Houston, TX "Novel catalytic chemistry of metalloporphyins" January, 1992.
32	Keystone Symposium on DNA Replication and Recombination, Taos, NM "Protein-protein interactions in the assembly of the presynaptic filament for homologous recombination" January, 1992.
33	Penn State University, University Park, PA "Controlling catalyst selectivity: A central problem in chemistry and biology" April, 1992.
34	National Institutes of Health, Bethesda, MD "The enzymology of homologous recombination" April, 1992.
35	ACS Symposium on Asymmetric Catalysis, San Francisco, CA "Synthesis and catalytic activity of chiral metalloporphyin complexes" April, 1992.
36	ACS Symposium on Bioinorganic Chemistry, San Francisco, CA "Biochemical and spectroscopic studies of a new metal-containing DNA-bindng motif" April, 1992.
37	University of Texas at Austin, Austin, TX "Protein Machines in Transcription and Recombination", April, 1992.
37	Southwestern Medical School, Dallas, TX "The Enzymology of Homologous Recombination", May, 1992.
38	NSF Workshop on Reactive Intermediates, Shelter Island, NY "Reactive intermediates in the rhodium porphyrin-catalyzed cyclopropanation of alkenes" September, 1992.
39	Scripps Institute, La Jolla, CA "Design and characterization of selective catalysts: Studies in asymmetric synthesis and macromolecular recognition" November 1992.
40	Hoerchst-Celanese Corporation, Corpus Christi, TX "Asymmetric catalysis using metalloporphyrins" August, 1993.
40	University of Texas at San Antonio, San Antonio, TX "Asymmetric catalysis using metalloporphyrins" September, 1993.
41	Symposium on DNA-Binding Drugs, American Chemical Society Southwest Regional Meeting, Austin, TX "Mechanism of transcription factor-DNA binding" October, 1993.
42	Oklahoma Medical Research Foundation, Oklahoma City, OK "Chemistry of transcriptional activation" March, 1994.
43	24th National Medicinal Chemistry Meeting, Salt Lake City, UT "Chemistry of transcriptional activation" June, 1994.
44	University of Utah School of Medicine, Salt Lake City, UT "Enzymology of Homologous Recombination" March 1995.
46	Boehriger-Manheim Corp., CT, "Semi-rational and completely irrational approaches to molecular design", July, 1995.
47	Rockefeller University, NY,NY, "Activator-TFIID interactions in the regulation of eukaryotic transcription", July, 1995.
45	ACS Symposium on Recent Advances In Metalloporphyrin Chemistry, American Chemical Society National Meeting, Chicago, IL, "Semi-rational design of porphyrin-based asymmetric catalysts", August, 1995.
48	Ambion Corp., Austin, TX, "Enzymology of homologous recombination" August, 1995.
49	Baylor Medical School, Houston, TX, "Protein machines involved in transcription and homologous recombination" November, 1995.
50	Penn. St. University, University Park, PA, "Protein machines involved in transcription and homologous recombination" November, 1995.
51	Michigan St. University, East Lansing, MI, "How do transcriptional activators and repressors work?" January, 1996.
52	Harvard University, Cambridge, MA, "Mechanistic studies of transcriptional regulation" April, 1996.
53	UT-Southwestern Medical School, Dallas, TX, "New methods for the study of multiprotein complexes" April, 1996.
54	Baylor University, Waco, TX, "New methods for the study of multiprotein complexes" April, 1996.
55	Scripps Research Institute, La Jolla, CA, "New methods for the study of multiprotein complexes" May, 1996.
56	ACS Symposium on the Chemistry of Gene Expression, American Chemical Society National Meeting, Orlando, FL, "New methods for the study of multiprotein transcription complexes", August, 1996.
57	University of Texas at Austin, Austin, TX, "New methods for the study of multiprotein transcription complexes", September, 1996.
58	Boston University, Boston, Mass., "New methods for the study of multiprotein transcription complexes", October, 1996.
59	MIT, Cambridge, Mass., "New insights into the regulation of eukaryotic transcription", October, 1996.
60	UT-Southwestern Medical Center, Dallas, TX, "New methods for the study and manipulation of multiprotein complexes", March, 1997.
61	Stratagene Corp., La Jolla, CA, ""New methods for the study and manipulation of multiprotein complexes", July, 1997.
62	Rice University, Houston, TX ""New methods for the study and manipulation of multiprotein complexes", September, 1997.
63	Boehringer-Ingelheim Corp., Stanford, CT ""New methods for the study and manipulation of multiprotein complexes", September, 1997.
64	U. of Massachusetts Medical School, Worchester, MA, ""New insights into the mechanism of action of transcriptional activators and repressors", October, 1997.
65	American Society of Microbiology Meeting, Houston, TX, ""New insights into the mechanism of action of transcriptional activators and repressors", November, 1997.
66	Baylor Medical School, Houston, TX "New methods for the study and manipulation of multiprotein complexes", November, 1997.
67	UT-San Antonio Health Science Center, San Antonio, TX, "New methods for the study and manipulation of multiprotein complexes", November, 1997.
68	UT-Southwestern Medical Center, Dallas, TX, "Magic bullet peptides: New tools for the manipulation of macromolecular complexes", April, 1998.
69	UT-Dallas, Dallas, TX "New methods for the study and manipulation of multiprotein complexes", September, 1998.
70	UT-Southwestern Medical Center, Dallas, TX, "New chemical and biological methods for the study of multiprotein complexes", December, 1998.
71	UT-Arlington, Arlington, TX "New chemical and biological methods for the study of multiprotein complexes", April 1999.
72	Southern Illinois University, Carbondale, IL "New chemical and biological methods for the study of multiprotein complexes", April, 1999.
73	New Mexico State University, Las Cruces, NM "New chemical and biological methods for the study of multiprotein complexes", November, 1999.
74	Peptides Gordon Research Conference, Ventura, CA "Library-derived peptides as reagents for the detection, manipulation and purification of protein complexes" February, 2000.
75	Stephen F. Austin University Biotechnology Symposium, Keynote Address, Nacagdoches, TX "Beyond antibodies: New magic bullets for the selective manipulation of biological pathways" February, 2000.
76	Life Technologies, Rockville, MD "Towards artificial antibodies" March, 2000.
77	UCSF, SF, CA "New methods for the study and manipulation of multiprotein complexes" April, 2000.
78	Touchstone Diabetes Center, UT-Southwestern, Dallas, TX "Chemical biotechnology" April, 2000.
79	Cambridge Healthtech Institute Conference on Recombinant Antibodies, Baltimore, MD "Epitope-binding peptides and peptidomimetic compounds: Towards low molecular weight antibody equivalents" June 2000.
80	Wyeth-Amerest Research Laboratories, Pearl River, NY "New methods for the study and manipulation of protein machines" June, 2000.
81	Sigma Corporation, St. Louis, MO "Towards artificial antibodies" July, 2000.
82	University of Texas at Dallas, Richardson, TX "New methods in chemical biology" September, 2000.
83	Keystone Meeting on Mechanisms of Eukaryotic Transcription, Sante Fe, NM "The 19S regulatory particle of the proteasome is required for efficient RNA polymerase II elongation" February, 2001.
84	Yale University, New Haven, Conn. "Chemical and biological approaches to understanding the role of the 19S proteasome regulatory complex in transcription" May, 2001.
85	Alfred Spinks Symposium on Chemical Biology, Royal Society Meeting, London, UK "The role of the 19S proteasome regulatory particle in transcription", May, 2001.
86	Gordon Conference on Bioorganic Chemistry, NH "Second generation proteomics" June, 2001.
87	British Association for Cancer Research Conference on Forging An Alliance Between Genomics, Proteomics And Chemical Biology, Chesam, Buckinghamshire, UK "Second generation proteomics" September, 2001.
88	Louisiana State Medical Center, Shreveport, LA "New insights into the role of the proteosome in transcription" January, 2001.
89	Trinity University, San Antonio, TX "Chemical biology in the post-genomic era" March, 2002.
90	Dana Farber Cancer Institute, Harvard Medical School, Boston, Mass. "Chemistry as a key tool in proteomics" March 2002.
91	Dana Farber Cancer Institute, Harvard Medical School, Boston, Mass. "New insights into the role of the proteasome in transcription" March 2002.
92	University of Illinois, Champaign-Urbana, IL "Second generation proteomics" March, 2002.
93	Washington State University, Pullman, WA "Second generation proteomics" April, 2002.
94	Rockefeller University, NY, NY "Chemical and biological studies of the proteasome and its role in transcription" April, 2002.
95	UCLA, Los Angeles, CA "Second generation proteomics" May 2002.
96	Scripps Research Institute, La Jolla, CA "Chemical and biological studies of the proteasome and its role in transcription" May, 2002.
97	National Cancer Institute-Innovative Technologies and Materials Conference, Chantilly, VA "Towards protein-detecting microarrays", July 2002.
98	California Institute of Techology, Pasadena, CA "Chemical tools for proteomics research" January, 2003.
99	Colorado State University. Boehringer-Ingelheim Lecturer, Fort Collins, CO "Chemical tools for proteomics research" February, 2003.
100	Keystone Meeting on Transcriptional Mechanisms, Sante Fe, NM "Novel roles of proteasomal proteins in transcription".
101	Johns Hopkins School of Medicine, Baltimore, MD "Chemical and biological studies of the proteasome and its role in transcription" February, 2003.
102	University of Michigan, Ann Arbor, MI "Chemical tools for proteomics research", April 2003.
103	University of Georgia, Athens, GA "Chemical tools for proteomics research", April, 2003.
104	Emory University School of Medicine, Atlanta, GA "Novel roles of the proteasome in transcription" April, 2003.
105	National Heart Lung and Blood Institute Symposium on High-Throughput Biology, Bethesda, MD "Towards protein-detecting microarrays based on synthetic capture agents", June, 2003.
106	Cornell University Summer School In Chemical Biology "Protein function arrays and protein-detecting arrays: The state of the art" Ithaca, NY, July, 2003.
107	Canadian Chemical Society Meeting, Ottawa, Canada "Chemical tools for proteomics research" August, 2003.
108	University of Wisconsin, Madison, WI "The many roles of ubiquitin-proteasome pathway proteins in transcription". September, 2003.
109	Harvard Medical School, Boston, MA "Multiple roles of ubiquitin/proteasome proteins in transcription" October, 2003.
110	Systems Biology Conference, St. Louis, MO "Protein-detecting microarrays" November, 2003.
111	Scripps Research Institute, La Jolla, CA "Protein-detecting microarrays", December, 2003.
112	Gordon Research Conference-The Chemistry & Biology of Peptides, Ventura, CA "Chemical Tools for Proteomics Research" February, 2004.
113	FASEB National Meeting, Washington, D.C. "Protein-Detecting Microarrays" April, 2004.
114	Gordon Research Conference-Bioorganic Chemistry, Andover, NH "New chemical tools for proteomics science" June, 2004.
115	American Heart Association's Council on Basic Cardiovascular Sciences: Stress Signals, Molecular Targets, and the Genome, Stevenson, WA "Protein-detecting microarrays" July, 2004.
116	Chips to Hits Conference, Boston, MA "Protein-detecting microarrays" September, 2004.
117	Yale University, New Haven, CT "New chemical tools for proteomics research" September, 2004.
118	Wayne State University, Detroit, MI "New chemical tools for proteomics research" October, 2004.
119	Abbott Endowed Lectureship, Texas A&M University, College Station, TX "New chemical tools for proteomics research" October, 2004.
120	University of Texas at Austin, Austin, TX "New chemical tools for proteomics research" October, 2004.
121	American Institute of Chemical Engineering Nation Meeting, Austin, TX "Protein-detecting microarrays" November, 2004.
122	University of Minnesota, Minneapolis, MN "Chemical tools for proteomics research", November, 2004.
123	Baylor College of Medicine, Houston, TX "New chemical tools for proteomics research" February, 2005.
124	NIH symposium: Exploring the Proteome III: The Challenge of Cellular Dynamics , Bethesda, MD "Methods for exploring the dynamics of protein-protein and protein-DNA interactions" April, 2005.
125	Burnham Institute Symposium "Frontiers in Chemical Biology"La Jolla, CA "Chemical tools for studying and manipulating the proteome" April, 2005.
126	American Peptide Society 19th Annual Symposium, San Diego, CA "Peptoid microarrays as tools for monitoring and manipulating the proteome" June, 2005.
127	Gordon Research Conference-Combinatorial Chemistry, Andover, NH "Functional and Analytical Applications of Combinatorial Peptoid Libraries In Biology and Medicine" August, 2005.
128	Cold Spring Harbor Symposium on Mechanisms of Eukaryotic Transcription, Cold Spring Harbor, NY "Dynamics of transcription factor-DNA interactions", September, 2005.
129	Hammon Cancer Center, UT-Southwestern Medical Center, Dallas, TX "Proteomic tools for medicine and biology" September, 2005.
130	Boston College, Boston, MA "New chemical tools for proteomics research" September, 2005.
131	American Heart Association National Meeting, Dallas, TX "Genome expression profiling" November, 2005.
132	Emory University, Atlanta, GA "Chemical tools for proteomics research" February, 2006.
133	Baylor College of Medicine, Houston, TX "Role of ubiquitin/proteasome pathway proteins in RNA polymerase II transcription" March, 2006.
134	ASBMB Meeting, San Francisco, CA "Small molecule microarrays as tools in chemistry and biology"April, 2006.
135	Experimental Biology Meeting, San Francisco, CA "Pharmacological manipulation of gene expression: Towards synthetic transcription factors" April 2006.
136	U.S. Chemistry and Chemical Engineering Council Meeting, Tuscon, AZ "Opportunities at the chemistry/biology interface"May, 2006.
137	NIH CMLD National Symposium, Boston, MA "Monitoring and manipulating the proteome with combinatorial peptoid libraries" June, 2006.
138	Bristol Myers-Squibb, Groton, Wallingford, CN "Monitoring and manipulating the proteome with combinatorial peptoid libraries" October, 2006.
139	UC-Riverside Chemical Genetics Program Retreat, Lake Arrowhead, CA "Chemistry and Biology of the Proteasome" October, 2006.
140	William & Lee University, Lexington, VA "Chemistry and Biology of the Proteasome" November, 2006.
141	University of Virginia, Charlottsville, VA "Chemistry and Biology of the Proteasome" November, 2006.
142	HUPO Annual Meeting, Long Beach, CA "New approach to immunobiomarker discovery" November, 2006.
143	American Heart Association Annual Meeting, Chicago, IL "New approach to immunobiomarker discovery" November, 2006.
144	UT Metroplex Days, Dallas, TX "Chemical tools to monitor and manipulate the proteome" November, 2006.
145	California Institute of Technology, Pasadena, CA "Chemical tools to monitor and manipulate the proteome" January, 2007.
146	Oxford University, Oxford, UK "Chemical tools to monitor and manipulate the proteome" February, 2007.
147	Sloan-Kettering Memorial Cancer Center, NY, NY "Chemical methods to monitor and manipulate the proteome" April, 2007.
148	University of Pennsylvania, Philadelphia, PA "Chemical methods to monitor and manipulate the proteome" May, 2007.
149	Merck Research Laboratories, Rahway, NJ "Chemical methods to monitor and manipulate the proteome"
150	Gordon Research Conference – Nucleic Acids, Andover, NH "Novel roles of the proteasome in modulating transcription factor function" June, 2007.
151	NIH Director's Pioneer Award Symposium, Bethesda, MD "Profiling immune system responses using peptoid microarrays" September, 2007.
152	UT-San Antonio School of Medicine, San Antonio, TX "Chemical methods to monitor and manipulate the proteome" September, 2007.
153	Kansas University, Lawrence, KN "Chemical methods to monitor and manipulate the proteome" September, 2007.
154	University of North Texas Health Science Center, Fort Worth, TX "Profiling immune system responses using peptoid microarraysÓ November, 2007.
155	Purdue University, Lafayette, IN "Chemical methods to monitor and manipulate the proteome" December, 2007.
156	Huntsman Cancer Center, University of Utah, Salt Lake City, UT "Intersections of Transcription and the Ubiquitin-Proteasome Pathway: Basic and Applied Studies" January, 2008.
157	Gordon Research Conference – Chemistry & Biology of Peptides, Ventura, CA "Peptoid libraries as a source of protein ligands" February, 2008.
158	Keystone Meeting on Beta Cell Biology, Snowbird, UT "Artificial Transactivators" April, 2008.
159	University of California, San Francisco, SF,CA "Immunobiomarker discovery using peptoid microarrays" April, 2008.
160	University of California at Irvine, Irvine, CA "Chemical methods to monitor and manipulate the proteome" April, 2008.
161	American Association of Clinical Chemistry: Proteomics Sub-Division Meeting, Seattle, WA "Chemical methods to monitor and manipulate the proteome" May, 2008.
162	British Society for Proteomics Research Annual Meeting, Cambridge, UK "Chemical methods to monitor and manipulate the proteome" July, 2008.
163	Scripps Florida Research Institute, Jupiter, FL "Chemical methods to monitor and manipulate the proteome" August, 2008.
164	American Chemical Society, Eli Lilly Award Symposium, Philadelphia, PA "Chemical methods to monitor and manipulate the proteome" August, 2008.
165	Texas A&M University, College Station, TX "Chemical methods to monitor and manipulate the proteome" October, 2008.
166	Georgia State University, Atlanta, GA "Intersections between eukaryotic transcription and the ubiquitin-proteasome pathway" November, 2008.
167	Millenium Pharmaceuticals, Cambridge, MA "Intersections between eukaryotic transcription and the ubiquitin-proteasome pathway" November, 2008.
168	University of California at Berkeley, Berkeley, CA "Chemical methods to monitor and manipulate the proteome" February, 2009.
169	University of Indiana School of Medicine, Indianapolis, IN "Chemical methods to monitor and manipulate the proteome" February, 2009.
170	Ohio State University, Columbus, OH "Chemical methods to monitor and manipulate the proteome" May, 2009.
171	University of Chicago, Chicago, IL "Chemical methods to monitor and manipulate the proteome" May, 2009.
172	National Institutes of Drug Addiction Symposium on Chemical Genetics, Portland, OR "Target-oriented chemical screening" July, 2009.
173	IUPAC Meeting, Glasgow, Scotland, UK "Chemical methods to monitor and manipulate the proteome" August, 2009.
174	NY Academy of Sciences, NY, NY "Chemical methods to monitor and manipulate the proteome" September, 2009.
175	Moffett Cancer Center, Tampa, FL "Chemical methods to monitor and manipulate the proteome" September, 2009.
176	NHLBI Capstone Symposium on Proteomic Technologies, Bethesda, MD "Chemical methods to monitor and manipulate the proteome" September, 2009.
177	University of Indiana School of Medicine, Indianapolis, IN "Chemical methods to monitor and manipulate the proteome" November, 2009.

Grant Support Active

1.	NO1-HV-28185 Kodadek (PI) — 10/02-9/11 Source: NIH (NHLBI) UT-Southwestern Center for Proteomics Research Role: Principal Investigator Development of new proteomics technology and its application to understanding the orexin-mediated effect on sleep homeostasis.
2.	DP10D00066301 Kodadek (PI) — 12/06-11/11 Source: NIH (Roadmap Program) NIH Director's Pioneer Award: Novel Chemistry To Monitor And Manipulate The Immune System Role: Principal Investigator Chemical libraries will be employed to identify antibodies and T cells associated with various disease states. These will be investigated both as diagnostic biomarkers and as therapeutic targets.
3.	1 P01-DK58398 Newgard (PI) — 6/06-5/11 Source: NIH (NIDDK) Manipulation of gene expression with small molecules Role: Principal Investigator of component project Development of novel technologies to monitor and manipulate beta cell function.
4.	1 RO1 GM087283 Kodadek (PI) — 8/09-7/11 Chemical Inhibitors of the Proteasomal ATPases Role: Principal Investigator Development of specific pharmacological inhibitors of the six proteasomal ATPases and other proteasome proteins.
5.	1 RO1 GM090294 Kodadek & Cravatt (PIs) — 9/09-8/14 Transformative RO1: Massively Parallel Identification of Protein Ligands Role: Co-Principal Investigator. This project will attempt to marry peptoid library screening with activity-based protein profiling (ABPP) in order to identify large numbers of specific protein ligands.
6.	1 RC1 AR058817& Karp (PI) — 9/09-8/11 High Throughput Screening of the AutoImmune Epitome Role: Sub-contractor This project will evaluate the diagnostic utility in lupus of antibody-binding peptoids identified using our technology for the discovery of IgG antibodies closely associated with a particular disease state. We will also develop new screening techniques for the discovery of these compounds.