Dr. Kelly has authored over 220 peer-reviewed publications published in prominent scientific journals including Science, Nature, Cell, New England Journal of Medicine, Proceedings of the National Academy of Sciences, Journal of the American Chemical Society, Biochemistry, and Journal of Medicinal Chemistry. For reprint requests, please click here.
1996:
- Zhang W, Diaz H, Kelly JW, Taylor JW. Examining the structural and functiona roles of the β-turn region in neuropeptide Y. Lett. Pep. Sci. 1996;3:133-142.
- Miroy GJ, Lai Z, Lashuel HA, Peterson SA, Strang C, Kelly JW. Inhibiting transthyretin amyloid fibril formation via protein stabilization. Proc. Natl. Acad. Sci. USA 1996;93:15051-15056.
- McWilliams K, Kelly JW. Synthesis and conformational preferences of a potential β-sheet nucleator based on the 9,9-dimethylxanthene skeleton. J. Org. Chem. 1996;61:7408-7414.
- Colon W, Lai Z, McCutchen SL, Miroy GJ, Strang CJ, Kelly JW. FAP mutations destabilize transthyretin facilitating conformational changes required for amyloid formation. In The Nature and Origin of Amyloid Fibrils (CIBA Foundation Symposium 199) Wiley, Chichester, 1996;228-242.
- Nesloney CL, Kelly JW. Progress towards understanding β-sheet structure. Bioorg. Med. Chem. 1996;4:739-766.
- Nesloney CN, Kelly JW. A 2,3'-substituted biphenyl-based amino acid facilitates the formation of a monomeric β-hairpin-like structure in aqueous solution at elevated temperature. J. Am. Chem. Soc. 1996;118:5836-5845.
- Nesloney CL, Kelly JW. Synthesis and hydrogen bonding capabilities of biphenyl-based amino acids designed to nucleate β-sheet structure. J. Org. Chem. 1996;61:3127-3137.
- Lai Z, Colon W, Kelly JW. The acid-mediated denaturation pathway of transthyretin yields a conformational intermediate that can self-assemble into amyloid. Biochemistry 1996;35:6470-6482.
- Kelly JW. Alternative conformations of amyloidogenic proteins govern their behavior. Curr. Opin. Struct. Biol. 1996;6:11-17.
- Choo DW, Schneider JP, Graciani NR, Kelly JW. A nucleated antiparallel β-sheet that folds and undergoes self-assembly: a template promoted folding strategy toward controlled molecular architectures. Macromolecules 1996;29:355-366.
