Dr. Kelly has authored over 220 peer-reviewed publications published in prominent scientific journals including Science, Nature, Cell, New England Journal of Medicine, Proceedings of the National Academy of Sciences, Journal of the American Chemical Society, Biochemistry, and Journal of Medicinal Chemistry. For reprint requests, please click here.
1998:
- Lashuel HA, Lai Z, Kelly JW. Characterization of the transthyretin acid denaturation pathways by analytical ultracentrifugation: implications for wild-type, V30M, and L55P amyloid fibril formation. Biochemistry 1998;37:17851-17864.
- Kelly JW. Overview of the biosynthesis of amino acids, peptides, porphyrins and alkaloids with a focus on the biosynthesis of aromatic amino acids. In Comprehensive Natural Products Chemistry, Vol 4, Amino Acids, Peptides, Porphyrins and Alkaloids. Kelly, J.W. (Ed.), Elsevier Science Ltd, Oxford, 1998;1-11.
- Peterson SA, Klabunde T, Lashuel HA, Purkey H, Sacchettini JC, Kelly JW. Inhibiting transthyretin conformational changes that lead to amyloid fibril formation. Proc. Natl. Acad. Sci USA 1998;95:12956-12960.
- Nettleton EJ, Sunde M, Lai Z, Kelly JW, Dobson CM, Robinson CV. Protein subunit interactions and structural integrity of amyloidogenic transthyretins: evidence from electrospray mass spectrometry. J. Mol. Biol. 1998;281:553-564.
- Xie Y, Lashuel HA, Miroy GJ, Dikler S, Kelly JW. Recombinant human retinol-binding protein refolding, native disulfide formation, and characterization. Prot. Exp. Purif. 1998;14:31-37.
- LaBrenz SR, Bekele H, Kelly JW. Enhancement of the water solubility of aromatic molecules via the Heck reaction. A comparison of ethano-ammonium, -carboxylate, and -phosphonate functional groups. Tetrahedron 1998;54:8671-8678.
- Patricelli MP, Lashuel HA, Giang DK, Kelly JW, Cravatt BF. Comparative characterization of a wild type and transmembrane domain-deleted fatty acid amide hydrolase: identification of the transmembrane domain as a site for oligomerization. Biochemistry 1998;37:15177-15187.
- Baures PW, Peterson SA, Kelly JW. Discovering transthyretin amyloid fibril inhibitors by limited screening. Bioorg. Med. Chem. 1998;6:1389-1401.
- Kelly JW. The alternative conformations of amyloidogenic proteins and their multi-step assembly pathways. Curr. Opin. Struct. Biol. 1998;8:101-106.
- Kelly JW. The environmental dependency of protein folding best explains prion and amyloid disease. Proc. Natl. Acad. Sci. USA 1998;95:930-932.
