Dr. Kelly has authored over 220 peer-reviewed publications published in prominent scientific journals including Science, Nature, Cell, New England Journal of Medicine, Proceedings of the National Academy of Sciences, Journal of the American Chemical Society, Biochemistry, and Journal of Medicinal Chemistry. For reprint requests, please click here.
2010:
- Choi S, Ong DST, Kelly JW. A Stilbene that Binds Selectively to Transthyretin in Cells and Remains Dark Until it Undergoes a Chemoselective Reaction to Create a Bright Blue Fluorescent Conjugate. J. Am. Chem. Soc. 2010;132:16043-16051.
- Choi S, Connelly S, Reixach N, Wilson IA, Kelly JW. Highly Chemoselective Small Molecules That Covalently Modify One Lysine in a Non-enzyme Protein in Plasma. Nat. Chem. Biol. 2010; 6:133-139.
- Choi S, Reixach N, Connelly S, Johnson SM, Wilson IA, Kelly JW. A Substructure Combination Strategy to Create Potent and Selective Transthyretin Kinetic Stabilizers that Prevent Amyloidogenesis and Cytotoxicity. J. Am. Chem. Soc. 2010; 132:1359-1370
- Connelly S, Choi S, Johnson SM, Kelly JW, Wilson IA. Structure-Based Design of Kinetic Stabilizers That Ameliorate the Transthyretin Amyloidoses. Curr. Op. Struct. Biol. 2010; 20:54-62.
- Hutt DM, Herman DM, Rodriques APC, Noel S, Pilewski JM, Matteson J, Hoch B, Kellner W, Kelly JW, Richardson J, Thomas PJ, Matsumura Y, Skach WR, Gentzsh M, Riordan JR, Sorscher EJ, Okiyonad T, Lukacs GL, Frizzell RA, Manning G, Gottesfeld JM, Balch WE. Reduced Histone Deacetylase 7 Activity Restores Function to Misfolded CFTR in Cystic Fibrosis. Nat. Chem. Biol. 2010;6:25-33.
- Johnson SM, Wiseman RL, Reixach N, Paulsson J, Choi S, Powers ET, Buxbaum JN, Kelly JW. Understanding and Ameliorating the Transthyretin Amyloidoses in Protein Misfolding Diseases: Current and Emerging Principles Eds: Ramirez-Alvarado M, Kelly JW, Dobson C. 2010 Wiley Blackwell.
- Naik S, Haque I, Degner N, Kornlayev B, Bomhoff G, Hodges J, Khorassani A-A, Katayama H, Morris J, Kelly JW, Seed J, Fisher MT. Identifying Protein Stabilizing Ligands using GroEL. Biopolymers 2010; 93:237-251.
- Ong DST, Mu T-W, Palmer, AE, Kelly JW. Endoplasmic reticulum Ca2+ increases enhance mutant glucocerebrosidase proteostasis. Nat. Chem. Biol. 2010; 6:424-432.
- Price JL, Shental-Bechor D, Dhar A, Turner MJ, Powers ET, Gruebele M,Levy Y, Kelly JW. Context-Dependent Effects of Asparagine Glycosylation on Pin WW Folding Kinetics and Thermodynamics. J. Am. Chem. Soc. 2010;132:15359-15367.
