Welcome to the Sauer Lab

Laboratory Address

The Scripps Research Institute
Mailstop IMM-24, Room R219
10550 North Torrey Pines Road
La Jolla, CA 92037, USA.

Lab phone : +1-858-784-7399
Fax: +1-858-784-7422

News from our lab

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Itk PH domain regulation by soluble IP₄: web version/pdf.

Importance of the G-loop Salt Bridge for Kinase Function and Inhibition: web version/pdf.

Selected recent publications

Barouch-Bentov, R., Che, J., Lee, C.C., Yang, Y., Herman, A., Jia, Y., Velentza, A., Watson, J., Sternberg, L., Kim, S., Ziaee, N., Miller, A., Jackson, C., Fujimoto, M., Young, M., Batalov, S., Liu, Y., Warmuth, M., Wiltshire, T., Cooke, M.P., and Sauer, K. (2009) A Conserved Salt Bridge in the G Loop of Multiple Protein Kinases Is Important for Catalysis and for in Vivo Lyn Function. Molecular Cell 33, 43-52. abstract

Huang, Y. H., Grasis, J., Miller, A. T., Xu, R., Soonthornvacharin, S., Andreotti, A. H., Tsoukas, C. D., Cooke, M. P., and Sauer, K. (2007) Positive Regulation of Itk PH Domain Function by Soluble IP₄. Science 316, 886-889. abstract (Free reprint under Publications)

Webpage implementation: Michelle Sauer