Crystals of Ebola virus GP bound to the human antibody KZ52


Crystal structure of the anti-Ebola virus antibody 13F6 in complex with its GP mucin-domain peptide epitope (yellow). The rare V lambda x light chain of the antibody (blue) is non-canonical in structure. Lee, et al. 2008. J. Mol Biol. 375:202-216.

Crystal structure of the trimeric, prefusion Ebola virus GP. GP1 attachment subunits (blues) are tied together by the GP2 fusion subunits (white). A rare neutralizing antibody from a human survivor (yellow) bridges GP1 to GP2. Lee, et al. 2008