McHEYZER-WILLIAMS LABORATORY

 
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RESEARCH PROJECTS

Regulating Adaptive Immunity

RESEARCH AREA  
1. Antigen-specific B Cell Immunity  



Clonal Evolution in B Cell Immunity
Memory B Cell Development
Consolidation of B Cell Memory
Plasma Cell Development
 
   
2. Antigen-specific Helper T Cell Immunity
 
  • Pre-Immune Diversity in the Th Cell Compartment
• Clonal Selection in the Th Cell Compartment
• What is the Nature of T Cell Help In vivo

 
   
3. Antigen-experienced Dendritic Cells  
  Isolate Antigen-Experienced DC Directly Ex Vivo
Evaluate the Impact of Adjuvant on DC Maturation and Function
Define How pMHCII+ DC Controls Adaptive Immunity