Employment Opportunities

Applying For Postdoctoral Positions At TSRI

You may apply for a postdoctoral position by sending your cover letter and curriculum vitae to the attention of the principal investigator as listed in each job vacancy, at the respective TSRI location (Florida or California). You may use the e-mail address listed for each investigator and electronically attach your curriculum vitae, or you may send your information to the principal investigator by mail as follows:

California:
The Scripps Research Institute
Attention: (name of principal investigator and maildrop)
10550 North Torrey Pines Road
La Jolla, CA 92037

Florida:
Scripps Florida
Division of The Scripps Research Institute
5353 Parkside Drive
Jupiter, FL 33458

Postdoctoral Positions Available at TSRI

Select one of the following departments that have positions available as of .

ADVANCED TECHNOLOGIES

Within the department of Advanced Technologies, the following Postdoctoral positions are available:

Principal Investigator: Paul J. Kenny
E-Mail: pjkenny@scripps.edu
URL: www.scripps.edu/florida/research/faculty.php?rec_id=8368

Duties & Responsibilities: A postdoctoral position is available at the newly created campus of The Scripps Research Institute in Palm Beach, Florida. This postition will involve investigating the neurobiological mechanisms underlying psychiatric disorders.

Requirements: The candidate should hav a background in behavioral neuroscience and/or molecular biology. Experience with stereotaxic surgery is desirable. For further information or to apply, contact Dr. Paul Kenny, pjkenny@scripps.edu. Please send a short letter outlining your suitability for the position, and a copy of your curriculum vitae that includes the names and full address of 3 professional references.

Location: Palm Beach County, FL

BIOCHEMISTRY

Within the department of Biochemistry, the following Postdoctoral positions are available:

No positions currently available

BIOMEDICAL RESEARCH

Within the department of Biomedical Research, the following Postdoctoral positions are available:

Principal Investigator: James Tam, Ph.D.
E-Mail: jamestam@scripps.edu

Duties & Responsibilities: Scripps Florida Biomedical Science is seeking a candidate for Post-Doctoral Fellow. This position will be part of a research group developing HIV therapeutics and vaccines. Responsibilities will include development of (I) peptide synthesis (II) ligation chemistry and (III) characterization of proteins. This position is available immediately.

Requirements: Must know solid phase peptide synthesis. Please send CV and list of at least 3 professional references to jamestam@scripps.edu.

Location: Palm Beach County, FL

INFORMATICS

Within the department of Informatics, the following Postdoctoral positions are available:

Principal Investigator: Nicholas Tsinoremas, Ph.D.
E-Mail: tsinorem@scripps.edu

Duties & Responsibilities: Scripps Florida is seeking a highly motivated Postdoctoral researcher interested in fungal genomics to work on the annotation and analysis of genome sequence data of Chrysosporium lucknowense C1. The genome sequencing project on this fungus has been completed and a full scale annotation project has begun to identify and describe the genes of this commercially important fungal species.

The Postdoctoral fellow will be responsible for the interpretation of the sequence data, mining and curation of resultant data, as well as preparing gene expression profiles that are incorporated into databases. He/she will prepare data for utilization by other scientists within defined timeframes and will be expected to present data at weekly and scientific meetings.

The successful candidate will be located in the Informatics Division at Scripps Florida (Jupiter, Florida) and will be expected to collaborate with scientists from Dyadic International, Inc.

Requirements: Qualified candidates should have a Ph.D. in Molecular Biology/ Microbial Genetics or Computational Biology. Familiarity with scripting languages is required. Preference will be given to candidates with extensive knowledge and experience in fungal biochemistry, physiology, and genetics. The position is initially for 2 years with the possibility of extension. Starting day is negotiable. Applicants should send a CV, cover letter and a list of at least 3 professional references to tsinorem@scripps.edu.

Location: Palm Beach County, FL

CELL BIOLOGY

Within the department of Cell Biology, the following Postdoctoral positions are available:

Principal Investigator: Lindsey A. Miles, Ph.D.
Maildrop:CVN 26
E-Mail: lmiles@scripps.edu

Duties & Responsibilities: A postdoctoral position is available to study regulation of the fibrinolytic system and its role in neurological function. The fibrinolytic system uses plasmin to degrade blood clots and also to generate protease activity for cell migration. Thrombotic diseases are the leading cause of death in the United States. The success candidate will study the function of cellular plasminigen receptors and the role of the plasminogen system in neurological functions.

Requirements: A Ph.D. in either biology, chemistry, biochemistry or neurobiology.

Location: La Jolla, CA

CHEMISTRY

Within the department of Chemistry, the following Postdoctoral positions are available:

No positions currently available

DRUG DISCOVERY

Within the department of Drug Discovery, the following Postdoctoral positions are available:

Principal Investigator: Dr. Peter Hodder
E-Mail: hodderp@scripps.edu

Duties & Responsibilities: Will be responsible for developing novel biochemical and cell-based functional high-throughput screening (HTS) assays for drug discovery. Perform molecular biology techniques, including subcloning and generation of expression vectors to create stable mammalian cell lines. Perform protein labeling, expression, purification. Perform optimization of biochemical and cell-based assays. Operate and troubleshoot automated liquid handling and analytical equipment. Utilize a variety of spreadsheet and data management software systems to generate, analyze and report data from research efforts.

Requirements: Ph.D. in Biology, Chemistry, or Engineering Sciences. Background in and experience with enzyme kinetics, protein expression/purification, mammalian cell culture expression vectors and cloning. Proficiency with operation of common laboratory and analytical equipment. Candidates must have excellent communication skills and a desire to work in a fast-paced, multi-disciplinary collaborative team. Please cend CV and a list of at least 3 professional references to Dr. Peter Hodder, hodderp@scripps.edu.

Location: Palm Beach County, FL

GENOME TECHNOLOGY

Within the department of Genome Technology, the following Postdoctoral positions are available:

No positions currently available

IMMUNOLOGY

Within the department of Immunology, the following Postdoctoral positions are available:

Principal Investigator: Ralph Reisfeld
Maildrop: IMM-13
E-Mail: reisfeld@scripps.edu
URL: www.scripps.edu/imm/reisfeld/

Duties & Responsibilities: A postdoctoral training position is available for a highly motivated and creative individual to work on a research project. It will focus on breast cancer stem cells with an emphasis on the elucidation of novel molecular markers, biological characteristics of such cells and validation of their therapeutic relavance for breast cancer.

Requirements: The individual should be highly self-motivated, have a Ph.D. and/or M.D. degree with a background in molecular biology or immunology. Must be able to effectively work within a mult-disciplinary group and have good communication skills. Interested candidates should provide their curriculum vitae and a list of at least 3 professional references to reisfeld@scripps.edu.

Location: La Jolla, CA

Principal Investigator: Dwight H. Kono
Maildrop: IMM-3
E-Mail: dkono@scripps.edu

Duties & Responsibilities: The Kono lab is seeking qualified individuals to participate in studies related to the molecular genetics of systemic autoimmunity in spontaneous mouse models. The program includes: 1) Genome-wide studies to identify predisposing genes in these models. 2) Creation of cogenic and subcogenic strains of mice to assess the role of candidate genes in the pathogenesis of component phenotypes. 3) Development of gene knockouts on predisposed background to address the role of cytokines, cell cycle and other immunologically-relevant genes. 4) Assessment of T cell homeostasic disturbances.

Requirements: Preferred applicants need good background in immunology, molecular biology and genetics. Salary and benefits commensurate with experience. Please send CV and a list of at least 3 professional references to dkono@scripps.edu.

Location: La Jolla, CA

Principal Investigator: Gary M. Bokoch
Maildrop: IMM-14
E-Mail: Bokoch@scripps.edu
URL: www.scripps.edu/imm/bokoch

Duties & Responsibilities: Research Associate/Postdoctor positions available in our lab, which studies Rho GTPases, how they are regulated, and how they control various cell activities (see TSRI website for Bokoch lab). We are currently particularly interested in cell motility, cytokineses, formation of reactive oxygen species via NADPH oxidases (Nox's) leukocyte function and how anthrax toxins might modulate innate immune responses. We seek motivated researchers with an interest in training in these subject areas.

Requirements: Candidates with knowledge of cell cycle/cytokinesis, the cytoskeleton (actin/myosin/microtubule), microscopy, oxidants, and/or who are accomplished molecular biologists are encouraged to apply. Please send curriculum vitae and letters of reference to: bokoch@scripps.edu.

Location: La Jolla, CA

Principal Investigator: Ralph Reisfeld
Maildrop: IMM-13
E-Mail: reisfeld@scripps.edu
URL: www.scripps.edu/imm/reisfeld/

Duties & Responsibilities: A Postdoctoral training position is available for a highly motivated and creative individual to work on a research project. It will focus on co-expression of chemokines and cytokines by oral DNA-based vaccines targeting transcription factor Fos-related antigen 1 (Fra-1) and their ability in priming and boosting T cell-mediated immune responses to eradicate spontaneous pulmonary metastases of breast carcinoma and prevent their recurrence.

Requirements: The individual should be highly self-motivated, have a Ph.D. and/or M.D. degree with a background in molecular biology or immunology. Must be able to effectivelly work within a multi-disciplinary group and have good communication skills. Interested candidates should provide their curriculum vitae, research interests and a list of at least 3 professional references to: reisfeld@scripps.edu.

Location: La Jolla, CA

Principal Investigator: Jiing-Dwan Lee
Maildrop: IMM-12
E-Mail: jdlee@scripps.edu

Duties & Responsibilities: Several postdoctoral positions are available at The Scripps Research Institute. Our lab studies the 4th Mammalian MAP kinase, BMK1/ERK5, signaling pathway and the tumor suppressor/protein chaperone, Tid1/Hsp40, how they are regulated, how they control diverse cellular responses and how they participate in cancer progression in animals (see Nature 1998;395:713, JCI 2004; 113:1138, Cancer Research 2005; 65:7699 and Nature Medicine 2006; 12:128). We seek motivated researchers with an interest in training in these subject areas.

Requirements: Applicants should have a Ph.D. or M.D. degree in a related area and general expertise in molecular biology, cellular biology and protein biochemistry. Experience in use of small animal models is preferred but not required. Please email curriculum vitae and a list of at least 3 professional references to Dr. Jiing-Dwan Lee at jdlee@scripps.edu.

Location: La Jolla, CA

Principal Investigator: Cheng Liu, M.D., Ph.D.
Maildrop: SP-233
E-Mail: chengliu@scripps.edu

Duties & Responsibilities: Postdoctoral positions are available investigating pathobiology and therapeutic interventions of cancer and atherothrombosis. Experiences with basic methodology in molecular biology, immunology, vascular biology and mouse models are preferred. Requirements: M.D. or/and Ph.D. in biomedical sciences.

Requirements: Postdoctoral degree and related experience.

Location: La Jolla, CA

Principal Investigator: Ulla G. Knaus, Ph.D.
Maildrop: IMM 28
E-Mail: uknaus@scripps.edu
URL: www.scripps.edu/imm/knaus/

Duties & Responsibilities: A postdoctoral position is available to investigage the response of the lung epithelium to Gram-positive and Gram-negative bacteria. The studies will focus on elucidation of GTPase-regulated signaling pathways resulting in changes in airway remodeling and pro-inflammatory processes.

Requirements: Applicants should have a recent Ph.D. or M.D. degree in a related area and general expertise in molecular biology, cellular biology and protein biochemistry. We are looking for motivated postdoctoral fellows with expertise in animal models, excellent cell culture skills and experience in microscopy. Good communication skills and a team personality are desired. Please e-mail CV and the names of three references to Dr. Ulla Knaus.

Location: La Jolla, CA

Principal Investigator: Erica Ollmann Saphire
Maildrop: IMM-212
E-Mail: erica@scripps.edu

Duties & Responsibilities: A postdoctoral position is available immediately using x-ray crystallography to understand the pathogenesis and immune evasion strategies of Ebola virus and other emerging/reemerging infectious diseases. Projects in the laboratory include viral envelope glycoproteins and components of the viral nucleocapsid. Strong collaborations with virologists, immunologists, and P4 facilities are in place for application of structural data to biological questions.

Requirements: The candidate should have a strong background in x-ray crystallography, molecular biology, and protein biochemistry and most importantly, enthusiasm for structural research. Please send c.v., names and contact information for three references to Assistant Professor Erica Ollmann Saphire: erica@scripps. edu; fax (858) 784-8360; or TSRI, mail code IMM-2.

Location: La Jolla, CA

Principal Investigator: Luc Teyton, M.D., Ph.D.
Maildrop: IMM-23
E-Mail: lteyton@scripps.edu

Duties & Responsibilities: Molecular Immunology of type 1 diabetes. Through usage of recombinant proteins the candidate will address some fundemental aspects of T cell selection and pathogenicity in the NOD mouse. Knowledge of protein purification, DNA technologies, single cell PCR and RNA display are a must.

Requirements: Motivation and dedication. A Ph.D. is required.

Location: La Jolla, CA

INFECTOLOGY

Within the department of Infectology, the following Postdoctoral position is available:

No positions currently available

MEDICINAL CHEMISTRY

Within the department of Medicinal Chemistry, the following Postdoctoral positions are available:

Principal Investigator: William R. Roush
E-Mail: roush@scripps.edu

Duties & Responsibilities: Postdoctoral position open for multi-step organic synthesis work; modern synthetic techniques and use of intrumentation such as HPLC-MS, HPLC, NMR and chromatography. Heterocyclic and medicinal chemistry and /or structure based drug design.

Requirements: Experience in multi-step organic synthesis. Good laboratory skills and proficiency in modern synthetic techniques and instrumentation such as HPLC-MS, PHLC, NMR and chromatography. Experience in heterocyclic and medicinal chemistry and/or structure based drug design desirable. Excellent communication and interpersonal skills. Please send Curriculum Vitae and a list of 3 professional references to roush@scripps.edu . For more information, please see Roush's website at www.scripps.edu/florida/biochem/roush .

Location: Palm Beach County, FL

MOLECULAR BIOLOGY

Within the department of Molecular Biology, the following Postdoctoral positions are available:

Principal Investigator: Scott Lesley
Maildrop: CB-167E
E-Mail: slesley@scripps.edu

Duties & Responsibilities: We are seeking candidates with a Ph.D. and 0-2 years' experience to participate in The Joint Center for Structural Genomics (JCSG) located at The Scripps Research Institute. The JCSG (http://www.jcsg.org) is a multi-center consortium and is one of four large-scale structural genomics centers funded by the Protein Structure Initiative which will produce between 100-150 structures of novel proteins per year. This group employs state of the art technology for protein expression and crystallization. Postdoctoral positions are avaliable to develop parallel approaches for characterizing active sites through studying small molecule interactions and for functional studies of key targets. This characterization will lead to functional assignment of genes and pathway mapping. Postdoctoral postions will have access to a wide range of resources and technology to apply to structure/function based research.

Requirements: We are seeking candidates with a Ph.D. and 0-2 years' experience. Successful candidates will have a background in biochemistry or related fields. Must be able to effectivlely work within a multi-disciplinary group and have good communication skills. Interested candidates should provide their CV and research interests along with a list of at least 3 professional references to Scott Lesley at slesley@scripps.edu.

Location: La Jolla, CA

Principal Investigator: Geoffrey Chang
Maildrop: CB-105
E-Mail: gchang@scripps.edu

Duties & Responsibilities: Postdoc position open. Will work with a lab subgroup in cloning and bacterial expression of eukaryotic membrane proteins. Specific duties include: buffer preparation, PCR amplification of genes from DNA clones, plasmid cloning, bacterial culture, protein expression screening with SDS-PAGE and western blots.

Requirements: Ph.D. with 1-3 years experience in molecular biology and protein biochemistry techniques. Good organizational skills. Experience in protein crystallization and x-ray crystallography a plus. Please send CV and list of at least 3 professional references to gchang@scripps.edu.

Location: La Jolla, CA

Principal Investigator: Qinghai Zhang
Maildrop: CB-256
E-Mail: qinghai@scripps.edu

Duties & Responsibilities: Postdoctoral position is open in the field of bioorganic chemistry, for design and synthesis of cell membrane simulation reagents. The candidates are mainly focused on chemical synthesis, and investigate the interaction of the synthesized molecules with membrane proteins for biophysics and structure biology research. The project involves multidisciplinary collaboration.

Requirements: The Individual should be highly self motivated, have a Ph.D. with a background in organic synthesis and an interest in cross-discipline approaches to challenging scientific problems. Please send your CV, a research summary and list of 3 references to Dr. Qinghai Zhang at qinghai@scripps.edu.

Location: La Jolla, CA

Principal Investigator: Scott Lesley
Maildrop: CB 167E
E-Mail: slesley@scripps.edu

Duties & Responsibilities: We are seeking post-doctoral candidates to participate in The Joint Center for Structural Genomics (JCSG) located at The Scripps Research Institute. The JCSG (http://www.jcsg.org) is a multi-center consortium and is one of four large-scale structural genomics centers funded by the Protein Structure Initiative which will produce between 100-150 structures of novel proteins per year. This group employs state of the art technology for protein expression and crystallization. Postdoctoral positions are available to develop parallel approaches for characterizing active sites through studying small molecule interactions and for functional studies of key targets. This characterization will lead to functional assignment of genes and pathway mapping. Postdoctoral positions will have access to a wide range of resources and technology to apply to structure/function based research.

Requirements: We are seeking candidates with a Ph.D. and 0-2 years of experience. Successful candidates will have a background in biochemistry or related fields. Must be able to effectively work within a multi-disciplinary group and have good communication skills. Interested candidates should provide their resume and research interests to Scott Lesley (slesley@scripps.edu).

Location: La Jolla, CA

Principal Investigator: Raymond Stevens
Maildrop: SR-101
E-Mail: stevens@scripps.edu
URL: http://stevens.scripps.edu/position.html

Duties & Responsibilities: Structural Neurobiology Postdoctoral Research Associate position available in the area of soluble protein structural biology and protein based therapeutic development. Access to novel expression/stabilization technologies, high throughput nanovolume crystallization, automated imaging, and automated beamline synchrotron facilities should greatly accedlerate structure based protein therapeutics.

Requirements: Applicants should send CV along with a list of at least three professional references to stevens@scripps.edu.

Location: La Jolla, CA

MOLECULAR & EXPERIMENTAL MEDICINE

Within the department of Molecular & Experimental Medicine, the following Postdoctoral positions are available:

Principal Investigator: Xiaohua Wu
Maildrop: MEM 255
E-Mail: xiaohwu@scripps.edu
URL: http://www.scripps.edu/mem/onc/wu

Duties & Responsibilities: A postdoctoral position is available for a highly motivated and creative individual who is interested in studying cell cycle checkpoint and DNA repair in mammalian cells. For further information, please visit http://www.scripps.edu/mem/onc/wu.

Requirements: A Ph.D. or M.D. degree with strong molecular biology is required. Please send curriculum vitae, a list of at least 3 professional references to xiaohwu@scripps.edu.

Location: La Jolla, CA

Principal Investigator: Thomas J. Kunicki
Maildrop: MEM-150
E-Mail: tomk@scripps.edu
URL: http://www.scripps.edu/mem/eht/kunicki

Duties & Responsibilities: Perform biochemical and molecular biology experiments to study structure and function of platelet proteins and glycoproteins. Characterize modifier gene loci that modulate the severity of bleeding and the efficiency of hemostasis in the mouse.

Requirements: Ph.D. required. Techniques of DNA and RNA isolation of characterization and cloning; experience in mouse husbandry and hemostasis assays. Please send CV and a list of at least 3 professional references to Dr. Thomas Kunicki at tomk@scripps.edu.

Location: La Jolla, CA

Principal Investigator: Dong-Er Zhang
Maildrop: MEM-L51
E-Mail: dzhang@scripps.edu

Duties & Responsibilities: We are looking for creative and highly motivated postdoctoral fellows (Ph.D. and/or M.D.) to study the function of protein modification by a ubiquitin like modifier ISG15 in signal transduction, stress response, and cancer development (related publications: JBC, 277:9976-9981; G&D, 17:455-460; G&D, 16:2207-2212) or the role of normal transcription factor AML1 in cell differentiation and abnormal fusion protein AML1-ETO in leukemogenesis (related publications: PNAS, 98:10398-10403; MCB, 21:5577-5590).

Requirements: Successful applicants should be well trained in at least one of the following areas: protein biochemistry, molecular biology, cell biology, hematology, and transgenic/knockout mice analysis. Please submit your letter of interest and C.V. to Dr. Dong-Er Zhang, The Scripps Research Institute, MEM-L51, 10550 North Torrey Pines Road, La Jolla, CA 92037, email: dzhang@scripps.edu.

Location: La Jolla, CA

MOLECULAR & INTEGRATIVE NEUROSCIENCES DEPARTMENT (MIND)

Within MIND, the following Postdoctoral positions are available:

Principal Investigator: Tamas Bartfai
Maildrop: SR-307
E-Mail: tbartfai@scripps.edu
URL: http://www.scripps.edu/research/dorriscenter/bartfai.html

Duties & Responsibilities: Helen Dorris Fellowship: A Postdoctoral position at the Harold L. Dorris Neurological Research Institute is available at The Scripps Research Institute, La Jolla.

Molecular Neurobiologist start date after October 1, 2006.

This fellowship is generously donated by Ms. Helen Dorris, a local philanthropist, and covers NIH level salary and benefits for 2 years. The previous fellows have gone on to promising academic careers.

The successful candidate will work within a research group on the receptor-ligand interactions and on intracellular signaling of the neuropeptide galanin (involved in Major Dpression, Schizophrenia, cognition and seizure control) or of the proinflammatory cytokine Interleukin 1. We study both transcription dependent and transcription independent signaling mechanisms, and routinely use DNA chipping to examine transcriptional changes and subsequently follow up expression of gene products in various functional, physiological and behavioral tests. The work will employ biochemical, molecular biological (mutagensis, polymorphisms, and transgenics) and cell biological techniques, and acute and chronic methods of neuropharmacology and immunopharmacology, and will be supported by ongoing work in the laboratory by electrophysiologists, morphologists, and behvaioral scientists.

The unique opportunity arises from the close collaboration within the same lab of all of these disciplines required for a deep understanding of any neurobiological problem. Our seminars and progress reports typically feature a collaboration between two or more disciplines.

Requirements: Please send CV and a list of at least 3 professional references to Marcia McRae (mjmcrae@scripps.edu) and Tamas Bartfai (tbartfai@scripps.edu).

Location: La Jolla, CA

Principal Investigator: Pietro Sanna, M.D.
Maildrop: CVN12
E-Mail: psanna@scripps.edu

Duties & Responsibilities: Post-doctoral positions are available immediately for motivated individuals to join dynamic multidisciplinary research team at The Scripps Research Institute to study the neurobiological bases of neural activity- and drug of abuse-induced synaptic plasticity with an emphasis on gene expression profiling. Research projects will involve cellular and molecular biology, electrophysiology, anatomy and behavior. These NIH funded positions offer a competitive salary and benefits package.

Requirements: Applicants should have a Ph.D., MD or equivalent degree. Successful candidates will be creative, highly motivated, able to work semi-independently, and have a strong background in either protein chemistry, molecular biology, pharmacology, or neurochemistry. We will provide training in complementary methodologies. Interested applicants should submit a CV, brief summary of research accomplishments and interests, as well as names of three references.

Location: La Jolla, CA

NEUROBIOLOGY/NEUROMEDICINE

Within the department of Neurobiology/Neuromedicine, the following Postdoctoral position is available:

Principal Investigator: Kathy Crossin
Maildrop: SBR-14
E-Mail: kcrossin@scripps.edu

Duties & Responsibilities: A postdoctoral position is available to examine the influence of mitochondrial activity in neuronal development. Approaches will include biochemical, proteomic, functional, and physiological analyses.

Requirements: Expertise in cell biology and either biochemistry or molecular biology is essential. Ph.D. or M.D. in a relevant scientific discipline. Please send CV and at least 3 professional references to kcrossin@scripps.edu.

Location: La Jolla, CA

THE SKAGGS INSTITUTE FOR CHEMICAL BIOLOGY

Within The Skaggs Institute for Chemical Biology, the following Postdoctoral positions are available:

No positions currently available

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