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Employment Opportunities
Applying For Postdoctoral Positions
You may apply for a postdoctoral position by sending your cover letter and curriculum vitae to the attention of the principal investigator as listed in each job vacancy, at the respective TSRI location (Florida or California). You may use the e-mail address listed for each investigator and electronically attach your curriculum vitae, or you may send your information to the principal investigator by mail as follows:
CALIFORNIA:
The Scripps Research Institute
10550 North Torrey Pines Road
La Jolla, CA 92037
FLORIDA:
Scripps Florida
Division of The Scripps Research Institute
130 Scripps Way
Jupiter, FL 33458
TSRI Faculty: Please help keep the information on this page current. See the Information Page on posting a postdoctoral position.
POSTDOCTORAL POSITIONS AVAILABLE AT TSRI
Select one of the following departments to view available positions:
- CANCER BIOLOGY
- CELL BIOLOGY
- CHEMICAL PHYSIOLOGY
- CHEMISTRY
- COMMITTEE ON THE NEUROBIOLOGY OF ADDICTIVE DISORDERS
- GENETICS
- IMMUNOLOGY & MICROBIAL SCIENCE
- INFECTOLOGY
- INFORMATICS
- METABOLISM & AGING
- MOLECULAR BIOLOGY
- MOLECULAR & EXPERIMENTAL MEDICINE
- MOLECULAR & INTEGRATIVE NEUROSCIENCES
- MOLECULAR THERAPEUTICS
- NEUROBIOLOGY
- THE SKAGGS INSTITUTE FOR CHEMICAL BIOLOGY
- TRANSLATIONAL RESEARCH INSTITUTE
CANCER BIOLOGY
Within the department of Cancer Biology, the following postdoctoral position is available:
Principal Investigator: Jun-Li Luo
E-Mail: jlluo@scripps.eduResearch Description: A postdoctoral position is available within the Department of Cancer Biology, Scripps Research Institute-Florida, to study signaling pathways in cancer biology. The newly established lab is focused on mechanistic and translational research in molecular signaling that connects epigenetic factors with genetic events during tumor genesis, progression and metastasis (Nature, 2007; 446(7136): 690-4. Cell, 2005; 121(7): 977-90. Cancer Cell, 2004; 6(3): 297-305.).
Requirements: The candidate should be Ph.D. or M.D. and Ph.D. with biomedical research experience. Candidate with stem cell research experience will be highly preferred. The starting time will be around August 1st, 2008. Interested applicants should submit a copy of CV, a brief statement of research skills, experiences, goals, and contact information (email address and phone number) of three references to: Dr. Jun-Li Luo, Assistant Professor in cancer biology, Email: jlluo@scripps.edu.
Location: Jupiter, FL
Principal Investigator: Tina Izard
E-Mail: izard@scripps.edu
URL: http://www.scripps.edu/florida/cancerbio/izard/Research Description: A position is available for post-doctoral fellow in Protein Crystallography. The lab is focused on unraveling the regulation of cell migration and morphogenesis, which relies on the cell's ability to form specific contacts with its neighbors or with the extracellular matrix (ECM) through dedicated adhesion receptors. Contacts with the ECM are directed by integrin receptors, which are unique in directing both outside-in and inside-out signaling pathways. Activation of integrin receptors triggers the rapid reorganization of the actin cytoskeleton and this relies on the function of talin and vinculin, which were previously thought to act as scaffolds that bridge integrin receptors to the actin cytoskeleton. Surprisingly, our structural, biochemical, and cell biological studies have revealed that these proteins function as direct signaling effectors that, by undergoing dramatic changes in their structures, transmit the outside-in signal. Successful candidates will work in a cutting-edge research environment that tackles this important new arena in cancer and cell biology. The laboratory has outstanding facilities for molecular biology; protein expression, purification, and biochemistry; and protein crystallography.
Requirements: We are seeking a PhD graduate to determine the crystal structures of several important cytoskeletal proteins. Candidates should have experience in crystal structure determination as well as an interest in the biology of cytoskeletal proteins. The position provides an outstanding training program in protein biochemistry and structure, and also in molecular and cellular biology, in a highly funded, dynamic, and team-oriented research program. Please send CV, a summary of research experience and interests, and names, addresses, e-mail and telephone numbers of 3 references to: izard@scripps.edu.
CELL BIOLOGY
Within the department of Cell Biology, the following postdoctoral positions are available:
Principal Investigator: Velia Fowler
E-Mail: velia@scripps.edu
URL: http://actin-ends.scripps.edu/Research Description: Actin cytoskeleton regulation of cell shape and tissue patterning during development; how perturbations in the actin cytoskeleton compromise tissue function. Projects center on molecular, cellular and functional studies of transgenic and knockout mice missing the actin filament capping protein, tropomodulin, and its binding partner, tropomyosin. Model systems include hexagonal packing geometry of epithelial and fiber cells in the eye lens, biogenesis of the membrane skeleton in red blood cells, and myofibril assembly and contraction in striated muscle. Approaches utilize histological analysis and in vivo imaging of fluorescent-tagged cells and proteins in mouse tissues, together with high-resolution visualization of cell shapes and actin cytoskeleton architecture using 3D reconstruction and quantitative image analysis software. Complementary studies in cultured cells using shRNA knockdowns are used to test molecular and cellular hypotheses of actin cytoskeleton regulation. Molecular mechanisms are also investigated using actin polymerization and protein-protein interaction assays, subcellular fractionation and western blotting, proteomics, and RNA-expression profiling. Functional and physiological consequences are tested using approaches specific for each cell and tissue system.
Requirements: Experience required in at least three of the following areas: molecular biology, cell culture, transfection, protein biochemistry, immunofluorescence and confocal microscopy, live cell microscopy, image analysis, histology, targeting vector technology, mouse genetics and embryonic development, primary cell isolation and culture from mouse tissues. Experience in cytoskeletal research desirable. Applicant will be expected to apply for a postdoctoral fellowship.
Ph.D. required in a biology-related discipline such as molecular/cell biology, developmental biology, biochemistry or genetics.
Please send your CV and a list of at least three professional references to velia@scripps.edu.
Location: La Jolla, CA
Principal Investigator: Ron Milligan
Maildrop: CB-227
E-Mail: carthur@scripps.edu
URL: http://www.scripps.edu/cb/milligan/Research Description: A postdoctoral position is available in the lab of Dr. Ron Milligan, Center for Integrative Molecular Biosciences at TSRI. The successful candidate will join a young energetic team involved in structural studies of membrane proteins and molecular motors using a host of electron microscopy techniques (cryo-EM, electron tomography, 2-D, helical, and single-particle reconstruction techniques). More information about our lab can be found on our web pages at http://www.scripps.edu/cb/milligan/.
Requirements: The applicant will have a Ph.D. and should be experienced in protein expression and purification. Experience in electron microscopy or other structure techniques (x-ray, NMR) is desirable but not required. Please send your CV, a statement of research interests, and a list of at least three professional references to carthur@scripps.edu.
CHEMICAL PHYSIOLOGY
Within the department of Chemical Physiology, the following postdoctoral positions are available:
Principal Investigator: Keri Mowen
Maildrop: IMM-11
E-Mail: kmowen@scripps.edu
URL: http://www.scripps.edu/chemphys/mowen/Research Description: A postdoctoral position is available for an enthusiastic, motivated, and independent individual in the area of molecular immunology. Our lab interests are in determining the role of peptidylarginine deiminases (PADs) and protein arginine methyltransferases (PRMTs) in T helper cell and mast cell function. Projects include examining novel substrates of PADs and PRMTs in T helper cells and mast cells and determining pathways that regulate PAD and PRMT function in these cell types, especially in the context of autoimmune models like inflammatory arthritis (see Molecular Cell 2004 15:559).
Requirements: Ph.D. in molecular biology, immunology, biochemistry, or cell biology is required. Good communication and organizational skills are a must. Interested candidates should submit their CV and a list of at least 3 professional references to kmowen@scripps.edu.
Location: La Jolla, CA
Principal Investigator: Martha Fedor
Maildrop: MB-35
E-Mail: mfedor@scripps.edu
URL: http://www.scripps.edu/chemphys/fedor/Research Description: An NIH-funded postdoctoral research position is available immediately in the research group of Martha J. Fedor, to investigate intracellular RNA recognition and mechanisms of RNA secondary structure assembly. This position offers opportunities for postdoctoral training in the application of quantitative methods for analysis of RNA structure and function in vivo.
Requirements: Candidates with experience in yeast molecular biology are particularly encouraged to apply. Please send your CV and a list of at least 3 professional references to mfedor@scripps.edu.
Location: La Jolla, CA
Principal Investigator: Martha Fedor
Maildrop: MB-35
E-Mail: mfedor@scripps.edu
URL:http://www.scripps.edu/chemphys/fedor/Research Description: An NIH-funded postdoctoral research position is open immediately in the research group of Martha J. Fedor to investigate mechanisms of RNA catalysis. This position offers the opportunity for postdoctoral training in mechanistic enzymology and biophysical studies of RNA enzymes.
Requirements: Candidates with experience in fluorescence assays and/or RNA biochemistry are particularly encouraged to apply. Interested candidates should submit their CV and a list of at least 3 professional references to mfedor@scripps.edu.
Location: La Jolla, CA
Principal Investigator: Hugh Rosen
Maildrop: ICND-118
E-Mail: sbrown@scripps.edu
URL: http://www.scripps.edu/chemphys/rosen/Research Description: We are seeking post-doctoral candidates to participate in The Scripps Comprehensive Center for Chemical Probe Optimization. The Screening Center is part of the NIH Roadmap initiative funded Molecular Libraries Probe Production Centers Network (MLPCN) , the goal of which is to identify and optimize bioactive small molecules that provide researchers the tools to broaden their investigations. The candidate will work closely with investigators interested in accessing the MLPN. Duties will include optimization and implementation of assays for a wide variety of molecular targets including enzymes, receptors and functional cell-based assays using a wide variety of technologies such as fluorescence, FP, TRF and reporter gene assays. The successful candidate will have access to state of the art detection and liquid handling technologies and will use these in the discovery of novel chemical probes.
Requirements: We are seeking candidates with a Ph.D. and at least 2 years of related experience in high throughput assay development. Successful candidates will have a background in biochemistry or related fields. Must be able to effectively work within a multi-disciplinary group and have excellent communication and meticulous record-keeping skills. Please send CV and a list of at least three professional references to sbrown@scripps.edu.
CHEMISTRY
Within the department of Chemistry, the following postdoctoral position is available:
COMMITTEE ON THE NEUROBIOLOGY OF ADDICTIVE DISORDERS (CNAD)
Within CNAD, the following postdoctoral positions are available:
Principal Investigator: Barbara Mason
Maildrop: TPC-5
E-Mail: mason@scripps.eduResearch Description: We are seeking a post-doctoral researcheer to conduct human laboratory studies and clinical trials in alcoholism and addictions. This position will also be involved in grant development and manuscript preparation.
Requirements: Must have completed a PhD, MD, or equivalent degree in a relevant discipline. Clinical trials experience is preferred; excellent writing and statistical skills; computer skills including proficiency in MS Word, Excel, and PowerPoint, and in medical literature searches. Please send CV and a list of at least three professional references to mason@scripps.edu.
GENETICS
Within the department of Genetics, the following postdoctoral positions are available:
Principal Investigator: Nathalie Franc
Maildrop: SP-273
E-Mail: nfranc@scripps.edu
URL: http://www.scripps.edu/genetics/Franc%20Lab/Homepage.htmlResearch Description: A postdoctoral position is available to study the molecular mechanisms of phagocytosis of apoptotic cells and bacteria using the fruitfly Drosophila melanogaster as a model organism. Please visit our website for more information.
Requirements: Ph.D. in any field of biology. The candidate should have strong conceptual and experimental background in Genetics, and/or Molecular and Cell Biology; experience with Drosophila Genetics is preferred but not absolutely essential. He/she should be independent, proactive, hard working and should enjoy working in a team; candidates will have at least one first-author publication in a good journal, and should have the potential and commitment to become self-funded in the short-term. Interested applicants should submit a CV, brief summary of research accomplishments and interests, and have three confidential professional references sent to nfranc@scripps.edu.
IMMUNOLOGY & MICROBIAL SCIENCE
Within the department of Immunology & Microbial Science, the following postdoctoral positions are available:
Principal Investigator: Cheng Liu
Maildrop: SP-233
E-Mail: chengliu@scripps.eduResearch Description: Postdoctoral positions are available investigating pathobiology and therapeutic interventions of cancer and atherothrombosis. Experiences with basic methodology in molecular biology, immunology, vascular biology and mouse models are preferred. Requirements: M.D. or/and Ph.D. in biomedical sciences.
Requirements: Postdoctoral degree and related experience.
Location: La Jolla, CA
Principal Investigator: Roberto Baccala
Maildrop: IMM-3
E-Mail: rbaccala@scripps.eduResearch Description: A postdoctoral position is available immediately in the Department of Immunology and Microbial Science for a highly motivated individual with strong background in immunology and molecular biology. Our laboratory focuses on genetic and mechanistic aspects of autoimmune diseases and cancer. The successful candidate will use animal models and molecular, biochemical, cellular and immunological approaches to study the pathogenesis of systemic autoimmunity, as in lupus, and demyelinating diseases of the central nervous system, as in multiple sclerosis and neuromyelitis optica.
Requirements: The candidate should have a PhD in immunology, molecular biology, or cellular biology; experience with mouse models; excellent organizational, record-keeping, as well as oral and written communication skills; and strong dedication and commitment to teamwork. Please send CV, a summary of research experience and interests, and name, address, email and telephone number of 3 professional references to rbaccala@scripps.edu.
Location: La Jolla, CA
Principal Investigator: Luc Teyton
Research Description: A postdoctoral position is available to study Molecular Immunology of type 1 diabetes. Through usage of recombinant proteins the candidate will address some fundemental aspects of T cell selection and pathogenicity in the NOD mouse. Knowledge of protein purification, DNA technologies, single cell PCR and RNA display are a must.
Maildrop: IMM-23
E-Mail: lteyton@scripps.eduRequirements: Motivation and dedication. A Ph.D. is required. Please send CV and at least three professional references to lteyton@scripps.edu.
Location: La Jolla, CA
Principal Investigator: Philippe Gallay
Maildrop: IMM-9
E-Mail: gallay@scripps.edu
URL: http://www.scripps.edu/research/faculty.php?rec_id=5582Research Description: A postdoctoral position is available to investigate the mechanisms that control the incorporation of viral glycoproteins (gp120/41) into the human immunodeficiency virus (HIV). The goal is to generate and identify compounds that block glycoproteins incorporation into HIV rendering the virus noninfectious.
Requirements: Candidates should have a PhD and laboratory experience in HIV as well as in molecular biology (cloning). Candidates should also have perfect English knowledge and computer skills. Please send CV and three professional references to gallay@scripps.edu.
Location: La Jolla, CA
INFECTOLOGY
Within the department of Infectology, the following postdoctoral position is available:
INFORMATICS
Within the department of Informatics, the following postdoctoral position is available:
MEDICINAL CHEMISTRY
Within the department of Medicinal Chemistry, the following postdoctoral position is available:
METABOLISM & AGING
Within the department of Metabolism & Aging, the following postdoctoral position is available:
MOLECULAR BIOLOGY
Within the department of Molecular Biology, the following postdoctoral positions are available:
Principal Investigator: Qinghai Zhang
Maildrop: CB-256
E-Mail: qinghai@scripps.eduResearch Description: Postdoctoral position is open in the field of organic synthesis and bioorganic chemistry. Experience on solution or solid phase peptide synthesis is desired but not necessary.
Requirements: The Individual should be highly self motivated, have a Ph.D. with a strong background in organic synthesis. Please send your CV, a research summary and list of 3 references to Dr. Qinghai Zhang at qinghai@scripps.edu.
Location: La Jolla, CA
Principal Investigator: Geoffrey Chang
Maildrop: CB-105
E-Mail: gchang@scripps.edu
URL: http://www.scripps.edu/mb/chang/Research Description: A postdoctoral position is available to work with a lab subgroup in cloning and expression of eukaryotic membrane proteins. Specific duties include: buffer preparation, PCR amplification of genes from DNA clones, plasmid cloning, bacterial culture, protein expression screening with SDS-PAGE and western blots.
Requirements: Ph.D. with 1-3 years experience in molecular biology and protein biochemistry techniques. Good organizational skills. Experience in protein crystallization and x-ray crystallography a plus. Please send CV and list of at least 3 professional references to gchang@scripps.edu.
Location: La Jolla, CA
Principal Investigator: Raymond Stevens
Maildrop: CB-207
E-Mail: stevens@scripps.edu
URL: http://stevens.scripps.edu/Research Description: Membrane Protein Postdoctoral Research Associate position in the area of membrane biochemistry and membrane protein crystallography. Access to novel expression/stabilization technologies, high throughput nanovolume crystallization, automated imaging, and automated beamline synchrotron facilities should greatly accelerate discovery of membrane protein crystallization and structure determination.
Requirements: Applicants must have successful experience with membrane proteins from a purification to crystallization or crystallization to structure background. Please send your CV and a list of at least three professional references to stevens@scripps.edu.
Location: La Jolla, CA
Principal Investigator: Takanori Otomo
Maildrop: CB-207
E-Mail: totomo@scripps.edu
URL: http://www.scripps.edu/mb/otomoResearch Description: A postdoctoral position is open in the laboratory of Takanori Otomo for a highly motivated, enthusiastic and independent candidate in the area of structural biology and biochemistry. The broad interest of the group is structural and functional basis of proteins involved in cell biology. We are currently focusing on mechanisms in autophagy, which is closely related to cellular trafficking, cytoskeleton, and organelle biogenesis.
Requirements: Candidates who have training in structural biology (X-ray crystallography and/or other methods) and/or biochemistry are desired. Please send your CV, a brief summary of research accomplishments and interests, and three professional references to totomo@scripps.edu.
MOLECULAR & EXPERIMENTAL MEDICINE
Within the department of Molecular & Experimental Medicine, the following postdoctoral positions are available:
Principal Investigator: Laura Crisa
Maildrop: MEM-L55
E-Mail: crisa@scripps.eduResearch Description: A postdoctoral position is available to join a research program aiming to characterize the development of bone marrow derived endothelial progenitors in vitro and in vivo in models of retinal neovascularization.
Requirements: Ph.D. in Molecular or Cellular Biology. Must have background in molecular and cellular biology tech-niques. Previous experience in immunology & microsurgery techniques is preferred. Please send CV and a list of at least 3 professional references to crisa@scripps.edu.
Location: La Jolla, CA
Principal Investigator: Nicholas Schork
Maildrop: SGM-300
E-Mail: nschork@scripps.eduResearch Description: The Scripps Translational Sciences Institute in La Jolla is seeking qualified individuals for a two-year post-doctoral fellowship investigating the design and implementation of analysis methods for high-dimensional neurogenomics studies.
Requirements: Qualified individuals must have a Ph.D. in neurosciences, biostatistics, statistics, genetics, or a related field. Responsibilities will involve conducting and participating in research that considers the integration of human imaging, brain gene expression, behavioral characterizations, and related phenotype data with genetic variation data. The fellow will work with a team of clinical and basic scientists on projects investigating a number of neuropsychiatric and neurodevelopmental disorders and phenotypes. The initial appointment will be for one year with the possibility of extension for an additional year based on a review and progress. Pay scale will be commensurate with experience and standard NIH guidelines. Please send your CV and a list of at least three professional references to nschork@scripps.edu.
Location: La Jolla, CA
Principal Investigator: Laura Crisa
Maildrop: MEM-L55
E-Mail: crisa@scripps.eduResearch Description: A postdoctoral position is available to perform microsurgery techniques on mice (i.e. pancreatic islet transplants); histological assessment of transplants; derive endothelial cell lines from bone marrow progenitors and study their immunological characteristics; determine genetic profile of tissue-derived vs. bone marrow derived endothelia isolated from transplants; defining proangiogenic myeloid and non-myeloid inflammatory cells supporting transplant engraftment.
Requirements: Ph.D. required. Basic cell biology and molecular biology techniques. Some knowledge in immunology is preferred. Please send CV and a list of at least 3 professional references to crisa@scripps.edu.
MOLECULAR & INTEGRATIVE NEUROSCIENCES DEPARTMENT (MIND)
Within MIND, the following postdoctoral positions are available:
Principal Investigator: Pietro Sanna
Maildrop: SP-2300
E-Mail: psanna@scripps.eduResearch Description: A post-doctoral position is available immediately for a motivated individual to join a dynamic multidisciplinary research team at The Scripps Research Institute to study the neurobiological bases of drug addiction with emphasis on genomic of drug and alcohol abuse. Research projects will involve gene expression assay by DNA microarrays and other molecular biological techniques. This NIH-funded position offers a competitive pay and benefits package.
Requirements:Applicants will have a Ph.D., MD or equivalent degree and have a strong background in behavioral pharmacology, or metabolism. Interested applicants should submit a CV, brief summary of research accomplishments and interests and three professional references to psanna@scripps.edu.
Location: La Jolla, CA
Principal Investigator: Claes Wahlestedt
E-Mail: clawah@scripps.eduResearch Description: Scripps Florida is seeking highly motivated individuals with proven research track records for post-doctoral fellowship positions. This is a great opportunity for individuals interested in leading-edge careers within academia as well as biotechnology or pharmaceutical companies. Projects are pursued in vitro as well as in vivo and will mostly concern functional characterization of disease gene candidates in Alzheimer’s disease or in schizophrenia. Our laboratory also has a strong interest in noncoding RNA. Fellows will work in a multidisciplinary, highly interactive environment with molecular biologists, pharmacologists, chemists, engineers and bioinformaticians.
Requirements:Successful applicants will have a Ph.D. (and/or MD) in pharmacology, molecular biology, cell biology, neurobiology and/or biochemistry, and 0-5 years postdoctoral experience. In addition, candidates should possess excellent communication skills, and work effectively both on teams and as an independent investigator. Applicants are requested to email their CV to Prof. C. Wahlestedt at clawah@scripps.edu.
Location: Jupiter, FL
Principal Investigator: Pietro Sanna
Maildrop: SP-2300
E-Mail: psanna@scripps.edu
Research Description: A post-doctoral position is available immediately for a motivated individual to join a dynamic multidisciplinary research team at The Scripps Research Institute to study gene regulation in neurobiology with DNA microarrays and next generation sequencing with a focus on drug and alcohol abuse. This NIH-funded position offers a competitive pay and benefits package.
Requirements:Applicants will have a Ph.D., MD or equivalent degree and have a strong background in genomics, molecular biology, behavioral pharmacology, or neurochemistry. Interested applicants should submit a CV, brief summary of research accomplishments and interests and three professional references to psanna@scripps.edu.
MOLECULAR THERAPEUTICS
Within the department of Molecular Therapeutics, the following postdoctoral positions are available:
Principal Investigator: Roy Periana
E-Mail: rperiana@scripps.eduResearch Description: These postdoctoral research positions will involve the investigation of hydrocarbon oxidation chemistry and small molecule activation.
Requirements: Candidates should be experts in organometallic or inorganic synthesis and characterization. The Scripps Energy Laboratories is oriented toward problem solving with close association to industrial partners. Candidates must be motivated to work in a fast-paced, industrial-like environment. Appointments are for one year with renewal of more years with satisfactory performance. Postdoctoral financial support is dependent on experience and expertise. Candidates should send a CV and letters of recommendations to Sel_pdoc@scripps.edu.
Location: Jupiter, FL
Principal Investigator: Paul Kenny
E-Mail: pjkenny@scripps.eduResearch Description: This position will involve investigation of the mechanisms underlying psychiatric disorders.
Requirements: The candidate should have a strong background in molecular biology and be enthusiastic about learning in vivo behavioral tests. In particular, candidates with expertise in mouse genetics are strongly encouraged to apply. For further information and to apply, please send: (1) a short letter of intent outlining your research experience and (2) a copy of your current CV that includes the names and addresses of three references to Dr. Paul Kenny, pjkenny@scripps.edu
NEUROBIOLOGY
Within the department of Neurobiology, the following postdoctoral positions are available:
Principal Investigator: Kathryn Crossin
Maildrop: SBR-14
E-Mail: kcrossin@scripps.eduResearch Description: A postdoctoral position is available to study the influence of redox state and mitochondria on signaling and differentiation in neural stem cells.
Requirements: Ph.D. in relevant biological field. Knowledge of cell biology and neural cell culture, molecular biology, and microscopic imaging are all helpful. Data analysis and statistics.Interested applicants should submit a CV, brief summary of research accomplishments and interests and three professional references to kcrossin@scripps.edu
THE SKAGGS INSTITUTE FOR CHEMICAL BIOLOGY
Within The Skaggs Institute for Chemical Biology, the following postdoctoral position is available:
TRANSLATIONAL RESEARCH INSTITUTE
Within the Translational Research Institute (TRI), the following postdoctoral positions are available:
Principal Investigator: Peter Hodder
E-mail: hodderpATscrippsDOTedu
TRI Division : Lead IDResearch Description: Will be responsible for developing and implementing novel biochemical and cell-based functional high-throughput screening (HTS) assays for drug discovery. Depending on the candidates expertise, perform enzymology, cell biology, or molecular biology techniques necessary to develop and implement HTS assays. This includes subcloning and generation of expression vectors to create stable mammalian cell lines, mammalian/bacterial protein expression and purification, mammalian/bacterial culture, determination of enzymatic parameters. Perform optimization of biochemical and cell-based assays. Operate and troubleshoot automated liquid handling and analytical equipment. Utilize a variety of spreadsheet and data management software systems to generate, analyze and report data from research efforts.
Requirements: Ph.D. in Biology, Chemistry, Microbiology, or Engineering Sciences. Background in and experience with enzyme kinetics, protein expression, protein purification (especially Äkta FPLC), and/or mammalian/bacterial culture, cloning and expression. Proficiency with operation of common equipment/instrumentation found in an enzymology, (e.g. stop-flow instrumentation) cell biology (e.g. tissue culture/transfection technology), molecular biology (e.g. gel electrophoresis/ western blots), microbiology and/or an analytical (e.g. LC-MS) laboratory. Candidates must have excellent communication skills and a desire to work in a fast-paced, multi-disciplinary collaborative team in a production-oriented setting similar to that found in the pharmaceutical industry. Specific HTS background not required. Please send CV and a list of at least 3 professional references to Dr. Peter Hodder, hodderpATscrippsDOTedu.
Location: Jupiter, FL
Principal Investigator: Derek Duckett
E-mail: ducketdr@scripps.edu
TRI Division : Discovery BiologyResearch Description: A position is available at The Scripps Research Institute, Scripps Florida for a highly motivated and creative postdoctoral research fellow. Working within The Translational Research Institute at Scripps Florida the candidate will focus on the basic biology of primary central nervous system cancers and aspects of neurodegeneration.
Requirements: Candidates should have obtained or are near completion of a doctoral degree in the life sciences. Prior experience in molecular and cell biology, confocal microscopy and in vivo tumor models would be an advantage. Please send CV, research summary and a list of references to ducketdr@scripps.edu.
Location: Jupiter, FL
Principal Investigator: Alex Pachori
E-mail: apachori@scripps.edu
TRI Division : Discovery BiologyResearch Description: We are seeking experienced candidates for postdoctoral fellowship in the epartment of drug discovery, division of pharmacology. The qualified candidate will support ongoing research projects on the development of novel anti-hypertensive agents. In addition, this person will undertake basic research projects to understand signaling pathways/mechanisms in the pathogenesis of hypertension/cardiovascular diseases
Requirements: Qualified candidates will have a Ph.D. in pharmacology/physiology, animal handling experience, drug dosing, basic molecular biology skills, cloning, development of knockout/transgenic mice and investigating signal ransduction pathways. Compensation will be commensurate with experience. Please send CV and a list of at least 3 professional references to apachori@scripps.edu.
Location: Jupiter, FL
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