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Publications

Han C, Song Y, Xiao H, Wang D, Franc NC, Jan LY and Jan Y-N. 2014. Epidermal Cell Are the Primary Phagocytes in the Fragmentation and Clearance of Degenerating Dendrites in Drosophila. Neuron (2014), [Abstract]
E. Van Goethem, E.A. Silva, H. Xiao, N.C. Franc. The Drosophila TRPP Cation Channel, PKD2 and Dmel/Ced-12 Act in Genetically Distinct Pathways during Apoptotic Cell Clearance. PLoS ONE. 7(2): e31488, (2012).
M.A. Gronski, J.M. Kinchen, I.J. Juncadella, N.C. Franc and K.S.Ravichandran. An essential role for calcium flux in phagocytes for apoptotic cell engulfment and the anti-inflammatory response. Cell Death Differ. 16(10):1323-31, (2009).
L. Cuttell*, A. Vaughan*, E. Silva, C.J. Escaron, M. Lavine, E. van Goethem, J.P. Eid, M. Quirin and N.C. Franc. Undertaker, a Drosophila Junctophilin links Draper-mediated Phagocytosis and Calcium Homeostasis. Cell 135(3):524-34, (2008). * These authors contributed equally to this work.
E.A. Silva, J. Burden and N.C. Franc. In vivo and in vitro methods for studying apoptotic cell engulfment in Drosophila. Methods Enzymol 446:39-59, (2008).
E. Silva*, H.W. Au-Yeung*, E. Van Goethem, J. Burden and N.C. Franc. Requirement for a Drosophila E3-ubiquitin ligase in phagocytosis of apoptotic cells. Immunity 27(4):585-96, (2007). *These authors contributed equally to this work.
Comments in: Immunity, 27(4):541-4, (2007). [Medline Abstract]
Featured in: Trends Cell Biol., 18(3):95-7, (2008). [Medline Abstract]
N.C. Franc. Phagocytosis of apoptotic cells in mammals, Caenorhabditis elegans and Drosophila melanogaster: molecular mechanisms and physiological consequences. Front Biosci1;7:d1298-313, (2002).
K. White, S. Lisi, P. Kurada, N. Franc and P. Bangs. Methods for studying apoptosis and phagocytosis of apoptotic cells in Drosophila tissues and cell lines. Methods Cell Biol. 66:321-38, (2001).
P. Bangs, N. Franc and White, K. Molecular mechanisms of cell death and phagocytosis in Drosophila. Cell Death Differ. 7(11):1027-34, (2000).
N.C. Franc and K. White. Innate recognition systems in insect immunity and development: new approaches in Drosophila. Microbes Infect. 2(3):243-50, (2000).
N.C. Franc, P. Heitzler, R.A. Ezekowitz and K. White. Requirement for croquemort in phagocytosis of apoptotic cells in Drosophila. Science 18;284(5422):1991-4, (1999).
N.C. Franc, K. White and R.A. Ezekowitz. Phagocytosis and development: back to the future. Curr Opin Immunol. 11(1):47-52, (1999).
N.C. Franc, J.L. Dimarcq, M. Lagueux, J. Hoffmann and R.A. Ezekowitz. Croquemort, a novel Drosophila hemocyte/macrophage receptor that recognizes apoptotic cells. Immunity 4(5):431-43, (1996).