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Publications

 

2017

Nowak RB, Papoin J, Gokhin DS, Casu C, Rivella S, Lipton JM, Blanc L, Fowler VM. Tropomodulin 1 controls erythroblast enucleation via regulation of F-actin in the enucleosome. Blood. 2017 Aug 31;130(9):1144-1155.

Sui Z, Gokhin DS, Nowak RB, Guo X, An X, Fowler VM. Stabilization of F-actin by tropomyosin isoforms regulates the morphology and mechanical behavior of red blood cells. Mol Biol Cell. 2017 Sep 15;28(19):2531-2542.

Cheng C, Fowler VM, Gong X. EphA2 and ephrin-A5 are not a receptor-ligand pair in the ocular lens. Exp Eye Res. 2017 Sep;162:9-17.

Fowler VM, Dominguez R. Tropomodulins and leiomodins: actin pointed end caps and nucleators in muscles. Biophys J. 2017 May 9;112(9):1742-1760.

Gokhin DS, Fowler VM. Software-based measurement of thin filament lengths: an open-source GUI for Distributed Deconvolution analysis of fluorescence images. J Microsc. 2017 Jan; 265(1):11-20

Cheng C, Nowak RB, Fowler VM. The lens actin filament cytoskeleton: diverse structures for complex functions. Exp Eye Res. 2017 Mar;156:58-71.

 

2016

Cheng C, Nowak RB, Biswas SK, Lo WK, FitzGerald PG, Fowler VMTropomodulin 1 regulation of actin is required for the formation of large paddle protrusions between mature lens fiber cells. Invest Ophthalmol Vis Sci. 2016 Aug 1;57(10):4084-4099.

Cheng C, Gokhin DS, Nowak RB, Fowler VM. Sequential application of glass coverslips to assess the compressive stiffness of the mouse lens: strain and morphometric analyses. J Vis Exp. 2016 May 3;(111).

Gokhin DS, Fowler VM. Feisty filaments: actin dynamics in the red blood cell membrane skeleton. Curr Opin Hematol. 2016 May;23(3):206-214.

 

2015

Gokhin DS, Ochala J, Domenighetti AA, Fowler VM Tropomodulin 1 directly controls thin filament length in both wild-type and tropomodulin 4-deficient skeletal muscle. Development. 2015 Dec 15;142(24):.

Liang R, Campreciós G, Kou Y, McGrath K, Nowak R, Catherman S, Bigarella CL, Rimmelé P, Zhang X, Gnanapragasam MN, Bieker JJ, Papatsenko D, Ma’ayan A, Bresnick E, Fowler V, Palis J, Ghaffari S. A systems approach identifies essential FOXO3 functions at key steps of terminal erythropoiesis. PLoS Genet. 2015 Oct 9;11(10):e1005526.

Sui Z, Nowak RB, Sanada C, Halene S, Krause DS, Fowler VM. Regulation of actin polymerization by tropomodulin3 controls megakaryocyte actin organization and platelet biogenesis. Blood. 2015 Jul 23;126(4):520-30.

Fischer RS, Fowler VM. Thematic minireview series: the state of the cytoskeleton in 2015.  J Biol Chem. 2015 Jul 10;290(28):17133-6.

Cheng C, Nowak RB, Gao J, Sun X, Biswas SK, Lo WK, Mathias RT, Fowler VMLens ion homeostasis relies on the assembly and/or stability of large connexin 46 gap junction plaques on the broad sides of differentiating fiber cells. Am J Physiol Cell Physiol. 2015 May 15;308(10):C835-C847.

Gokhin DS, Nowak RB, Khoory JA, de la Piedra A, Ghiran IC, Fowler VM. Dynamic actin filaments control the mechanical behavior of the human red blood cell membrane. Mol Biol Cell. 2015 May 1;26(9):1699-710.

 

2014

Gokhin DS, Dubuc EA, Lian KQ, Peters LL, Fowler VM. Alterations in thin filament length during postnatal skeletal muscle development and aging in mice. Front Physiol. 2014 Sep 29;5:375.

Yuen M, Sandaradura SA, Dowling JJ, Kostyukova AS, Moroz N, Quinlan KG, Lehtokari VL, Ravenscroft G, Todd EJ, Ceyhan-Birsoy O, Gokhin DS, Maluenda J, Lek M, Nolent F, Pappas CT, Novak SM, D’Amico A, Malfatti E, Thomas BP, Gabriel SB, Gupta N, Daly MJ, Ilkovski B, Houweling PJ, Davidson AE, Swanson LC, Brownstein CA, Gupta VA, Medne L, Shannon P, Martin N, Bick DP, Flisberg A, Holmberg E, Van den Bergh P, Lapunzina P, Waddell LB, Sloboda DD, Bertini E, Chitayat D, Telfer WR, Laquerrière A, Gregorio CC, Ottenheijm CA, Bönnemann CG, Pelin K, Beggs AH, Hayashi YK, Romero NB, Laing NG, Nishino I, Wallgren-Pettersson C, Melki J, Fowler VM, MacArthur DG, North KN, Clarke NF. Leiomodin-3 dysfunction results in thin filament disorganization and nemaline myopathy. J Clin Invest. 2014 Nov 3;124(11):4693-708.

Lewis RA, Yamashiro S, Gokhin DS, Fowler VM. Functional effects of mutations in the tropomyosin-binding sites of tropomodulin1 and tropomodulin3. Cytoskeleton. 2014 Jul;71(7):395-411.

Yamashiro S, Gokhin DS, Sui Z, Bergeron SE, Rubenstein PA, Fowler VM. Differential actin-regulatory activities of tropomodulin1 and tropomodulin3 with diverse tropomyosin and actin isoforms. J Biol Chem. 2014 Apr 25;289(17):11616-29.

McKeown CR, Nowak RB, Gokhin DS, Fowler VM. Tropomyosin is required for cardiac morphogenesis, myofibril assembly, and formation of adherens junctions in the developing mouse embryo. Dev Dyn. 2014 Jun;243(6):800-17.

Gokhin DS, Tierney MT, Sui Z, Sacco A, Fowler VM. Calpain-mediated proteolysis of tropomodulin isoforms leads to thin filament elongation in dystrophic skeletal muscle. Mol Biol Cell. 2014 Mar;25(6):852-65.

Sui Z, Nowak RB, Bacconi A, Kim NE, Liu H, Li J, Wickrema A, An XL, Fowler VM. Tropomodulin3-null mice are embryonic lethal with anemia due to impaired erythroid terminal differentiation in the fetal liver. Blood. 2014 Jan 30;123(5):758-67.

Ochala J, Gokhin DS, Iwamoto H, Fowler VM. Pointed-end capping by tropomodulin modulates actomyosin crossbridge formation in skeletal muscle fibers. FASEB J. 2014 Jan;28(1):408-15.

 

2013

Fowler VM. The human erythrocyte plasma membrane: a Rosetta stone for decoding membrane-cytoskeleton structure. Curr Top Membr. 2013;72C:39-88.

Gokhin DS, Fowler VM. A two-segment model for thin filament architecture in skeletal muscle. Nat Rev Mol Cell Biol. 2013 Feb;14(2):113-9.

 

2012

Gokhin DS, Nowak RB, Kim NE, Arnett EE, Chen AC, Sah RL, Clark JI, Fowler VM. Tmod1 and CP49 synergize to control the fiber cell geometry, transparency, and mechanical stiffness of the mouse lens. PLoS One. 2012;7(11):e48734.

Ochala J, Gokhin DS, Pénisson-Besnier I, Quijano-Roy S, Monnier N, Lunardi J, Romero NB, Fowler VM. Congenital myopathy-causing tropomyosin mutations induce thin filament dysfunction via distinct physiological mechanisms. Hum Mol Genet. 2012 Oct 15;21(20):4473-85.

Yamashiro S, Gokhin DS, Kimura S, Nowak RB, Fowler VM. Tropomodulins: pointed-end capping proteins that regulate actin filament architecture in diverse cell types. Cytoskeleton. 2012 Jun;69(6):337-70.

Nowak RB, Fowler VM. Tropomodulin 1 constrains fiber cell geometry during elongation and maturation in the lens cortex. J Histochem Cytochem. 2012 Jun;60(6):414-27.

Damani S, Bacconi A, Libiger O, Chourasia AH, Serry R, Gollapudi R, Goldberg R, Rapeport K, Haaser S, Topol S, Knowlton S, Bethel K, Kuhn P, Wood M, Carragher B, Schork NJ, Jiang J, Rao C, Connelly M, Fowler VM, Topol EJ. Characterization of circulating endothelial cells in acute myocardial infarction. Sci Transl Med. 2012 Mar 21;4(126):126ra33.

Gokhin DS, Kim NE, Lewis SA, Hoenecke HR, D’Lima DD, Fowler VM. Thin-filament length correlates with fiber type in human skeletal muscle. Am J Physiol Cell Physiol. 2012 Feb;302(3):C555-65.

 

2011

Gokhin DS, Fowler VM. The sarcoplasmic reticulum: actin and tropomodulin hit the links. Bioarchitecture. 2011 Jul;1(4):175-179.

Gokhin DS, Fowler VM. Tropomodulin capping of actin filaments in striated muscle development and physiology. J Biomed Biotechnol. 2011;2011:103069.

Bao N, Kodippili GC, Giger KM, Fowler VM, Low PS, Lu C. Single-cell electrical lysis of erythrocytes detects deficiencies in the cytoskeletal protein network. Lab Chip. 2011 Sep 21;11(18):3053-6.

Gokhin DS, Fowler VM. Cytoplasmic gamma-actin and tropomodulin isoforms link to the sarcoplasmic reticulum in skeletal muscle fibers. J Cell Biol. 2011 Jul 11;194(1):105-20.

Nicolaou KC, Jiang X, Lindsay-Scott PJ, Corbu A, Yamashiro S, Bacconi A, Fowler VM. Total synthesis and biological evaluation of monorhizopodin and 16-epi-monorhizopodin. Angew Chem Int Ed Engl. 2011 Feb 1;50(5):1139-44.

Fath T, Fischer RS, Dehmelt L, Halpain S, Fowler VM. Tropomodulins are negative regulators of neurite outgrowth. Eur J Cell Biol. 2011 Apr;90(4):291-300.

Leonard M, Zhang L, Zhai N, Cader A, Chan Y, Nowak RB, Fowler VM, Menko AS. Modulation of N-cadherin junctions and their role as epicenters of differentiation-specific actin regulation in the developing lens. Dev Biol. 2011 Jan 15;349(2):363-77.

 

2010

Yamashiro S, Speicher KD, Speicher DW, Fowler VM. Mammalian tropomodulins nucleate actin polymerization via their actin monomer binding and filament pointed end-capping activities. J Biol Chem. 2010 Oct 22;285(43):33265-80.

Moyer JD, Nowak RB, Kim NE, Larkin SK, Peters LL, Hartwig J, Kuypers FA, Fowler VM. Tropomodulin 1-null mice have a mild spherocytic elliptocytosis with appearance of tropomodulin 3 in red blood cells and disruption of the membrane skeleton. Blood. 2010 Oct 7;116(14):2590-9.

Gokhin DS, Lewis RA, McKeown CR, Nowak RB, Kim NE, Littlefield RS, Lieber RL, Fowler VM. Tropomodulin isoforms regulate thin filament pointed-end capping and skeletal muscle physiology. J Cell Biol. 2010 Apr 5;189(1):95-109.

 

2009

Nowak RB, Fischer RS, Zoltoski RK, Kuszak JR, Fowler VM. Tropomodulin1 is required for membrane skeleton organization and hexagonal geometry of fiber cells in the mouse lens. J Cell Biol. 2009 Sep 21;186(6):915-282.

Castillo A, Nowak R, Littlefield KP, Fowler VM, Littlefield RS. A nebulin ruler does not dictate thin filament lengths. Biophys J. 2009 Mar 4;96(5):1856-65.

 

2008

McKeown CR, Nowak RB, Moyer J, Sussman MA, Fowler VM. Tropomodulin1 is required in the heart but not the yolk sac for mouse embryonic development. Circ Res. 2008 Nov 21;103(11):1241-8. 4.

Littlefield RS, Fowler VM. Thin filament length regulation in striated muscle sarcomeres: pointed-end dynamics go beyond a nebulin ruler. Semin Cell Dev Biol. 2008 Dec;19(6):511-9.

Ilkovski B, Mokbel N, Lewis RA, Walker K, Nowak KJ, Domazetovska A, Laing NG, Fowler VM, North KN, Cooper ST. Disease severity and thin filament regulation in M9R TPM3 nemaline myopathy. J Neuropathol Exp Neurol. 2008 Sep;67(9):867-77.

 

2007

Weber KL, Fischer RS, Fowler VM. Tmod3 regulates polarized epithelial cell morphology. J Cell Sci. 2007 Oct 15;120(Pt 20):3625-32.

 

2006

Fischer RS, Yarmola EG, Weber KL, Speicher KD, Speicher DW, Bubb MR, Fowler VM. Tropomodulin 3 binds to actin monomers. J Biol Chem. 2006 Nov 24;281(47):36454-65.

Kalfa TA, Pushkaran S, Mohandas N, Hartwig JH, Fowler VM, Johnson JF, Joiner CH, Williams DA, Zheng Y. Rac GTPases regulate the morphology and deformability of the erythrocyte cytoskeleton. Blood. 2006 Dec 1;108(12):3637-45

Fowler VM, McKeown CR, Fischer RS. Nebulin: does it measure up as a ruler? Curr Biol. 2006 Jan 10;16(1):R18-20.

 

2005

Schmid M, Nanda I, Hoehn H, Schartl M, Haaf T, Buerstedde JM, Arakawa H, Caldwell RB, Weigend S, Burt DW, Smith J, Griffin DK, Masabanda JS, Groenen MA, Crooijmans RP, Vignal A, Fillon V, Morisson M, Pitel F, Vignoles M, Garrigues A, Gellin J, Rodionov AV, Galkina SA, Lukina NA, Ben-Ari G, Blum S, Hillel J, Twito T, Lavi U, David L, Feldman MW, Delany ME, Conley CA, Fowler VM, Hedges SB, Godbout R, Katyal S, Smith C, Hudson Q, Sinclair A, Mizuno S. Second report on chicken genes and chromosomes 2005. Cytogenet Genome Res. 2005;109(4):415-79.

Gupton SL, Anderson KL, Kole TP, Fischer RS, Ponti A, Hitchcock-DeGregori SE, Danuser G, Fowler VM, Wirtz D, Hanein D, Waterman-Storer CM. Cell migration without a lamellipodium: translation of actin dynamics into cell movement mediated by tropomyosin. J Cell Biol. 2005 Feb 14;168(4):619-31.

 

2004

Ehler E, Fowler VM, Perriard JC. Myofibrillogenesis in the developing chicken heart: role of actin isoforms and of the pointed end actin capping protein tropomodulin during thin filament assembly. Dev Dyn. 2004 Apr;229(4):745-55.

 

2003

Fritz-Six KL, Cox PR, Fischer RS, Xu B, Gregorio CC, Zoghbi HY, Fowler VM. Aberrant myofibril assembly in tropomodulin1 null mice leads to aborted heart development and embryonic lethality. J Cell Biol. 2003 Dec 8;163(5):1033-44.

Fischer RS, Fowler VM. Tropomodulins: life at the slow end. Trends Cell Biol. 2003 Nov;13(11):593-601.

Mudry RE, Perry CN, Richards M, Fowler VM, Gregorio CC. The interaction of tropomodulin with tropomyosin stabilizes thin filaments in cardiac myocytes. J Cell Biol. 2003 Sep 15;162(6):1057-68.

Taraschi TF, O’Donnell M, Martinez S, Schneider T, Trelka D, Fowler VM, Tilley L, Moriyama Y. Generation of an erythrocyte vesicle transport system by Plasmodium falciparum malaria parasites. Blood. 2003 Nov 1;102(9):3420-6.

Fowler VM, Greenfield NJ, Moyer J. Tropomodulin contains two actin filament pointed end-capping domains. J Biol Chem. 2003 Oct 10;278(41):40000-9.

Fischer RS, Quinlan RA, Fowler VM. Tropomodulin binds to filensin intermediate filaments. FEBS Lett. 2003 Jul 17;547(1-3):228-32.

Cox PR, Fowler V, Xu B, Sweatt JD, Paylor R, Zoghbi HY. Mice lacking tropomodulin-2 show enhanced long-term potentiation, hyperactivity, and deficits in learning and memory. Mol Cell Neurosci. 2003 May;23(1):1-12.

Fischer RS, Fritz-Six KL, Fowler VM. Pointed-end capping by tropomodulin3 negatively regulates endothelial cell motility. J Cell Biol. 2003 Apr 28;161(2):371-80.

 

2002

Wagner LM, Fowler VM, Takemoto DJ. The interaction and phosphorylation of tropomodulin by protein kinase Calpha in N/N 1003A lens epithelial cells. Mol Vis. 2002 Oct 22;8:394-406.

Littlefield R, Fowler VM. A minor actin catastrophe. Nat Cell Biol. 2002 Sep;4(9):E209-11.

Greenfield NJ, Fowler VM. Tropomyosin requires an intact N-terminal coiled coil to interact with tropomodulin. Biophys J. 2002 May;82(5):2580-91.

Littlefield R, Fowler VM. Measurement of thin filament lengths by distributed deconvolution analysis of fluorescence images. Biophys J. 2002 May;82(5):2548-64.

 

2001

Mardahl-Dumesnil M, Fowler VM. Thin filaments elongate from their pointed ends during myofibril assembly in Drosophila indirect flight muscle. J Cell Biol. 2001 Dec 10;155(6):1043-53.

Littlefield R, Almenar-Queralt A, Fowler VM. Actin dynamics at pointed ends regulates thin filament length in striated muscle. Nat Cell Biol. 2001 Jun;3(6):544-51.

Conley CA, Fritz-Six KL, Almenar-Queralt A, Fowler VM. Leiomodins: larger members of the tropomodulin (Tmod) gene family. Genomics. 2001 Apr 15;73(2):127-39.

Lee A, Morrow JS, Fowler VM. Caspase remodeling of the spectrin membrane skeleton during lens development and aging. J Biol Chem. 2001 Jun 8;276(23):20735-42.

McElhinny AS, Kolmerer B, Fowler VM, Labeit S, Gregorio CC. The N-terminal end of nebulin interacts with tropomodulin at the pointed ends of the thin filaments. J Biol Chem. 2001 Jan 5;276(1):583-92.

 

2000

Woo MK, Lee A, Fischer RS, Moyer J, Fowler VM. The lens membrane skeleton contains structures preferentially enriched in spectrin-actin or tropomodulin-actin complexes. Cell Motil Cytoskeleton. 2000 Aug;46(4):257-68.

Fowler V. Models for actin filament organization in the erythrocyte membrane skeleton. Blood. 2000 Jul 15;96(2):780-2.

Nanda I, Zend-Ajusch E, Shan Z, Grützner F, Schartl M, Burt DW, Koehler M, Fowler VM, Goodwin G, Schneider WJ, Mizuno S, Dechant G, Haaf T, Schmid M. Conserved synteny between the chicken Z sex chromosome and human chromosome 9 includes the male regulatory gene DMRT1: a comparative (re)view on avian sex determination. Cytogenet Cell Genet. 2000;89(1-2):67-78.

Lee A, Fischer RS, Fowler VM. Stabilization and remodeling of the membrane skeleton during lens fiber cell differentiation and maturation. Dev Dyn. 2000 Mar;217(3):257-70.

Fischer RS, Lee A, Fowler VM. Tropomodulin and tropomyosin mediate lens cell actin cytoskeleton reorganization in vitro. Invest Ophthalmol Vis Sci. 2000 Jan;41(1):166-74.

 

1999

Weber A, Pennise CR, Fowler VM. Tropomodulin increases the critical concentration of barbed end-capped actin filaments by converting ADP.P(i)-actin to ADP-actin at all pointed filament ends. J Biol Chem. 1999 Dec 3;274(49):34637-45.

Conley CA, Fowler VM. Localization of the human 64kD autoantigen D1 to myofibrils in a subset of extraocular muscle fibers. Curr Eye Res. 1999 Oct;19(4):313-22.

Almenar-Queralt A, Lee A, Conley CA, Ribas de Pouplana L, Fowler VM. Identification of a novel tropomodulin isoform, skeletal tropomodulin, that caps actin filament pointed ends in fast skeletal muscle. J Biol Chem. 1999 Oct 1;274(40):28466-75.

Almenar-Queralt A, Gregorio CC, Fowler VM. Tropomodulin assembles early in myofibrillogenesis in chick skeletal muscle: evidence that thin filaments rearrange to form striated myofibrils. J Cell Sci. 1999 Apr;112 ( Pt 8):1111-23.

 

1998

Littlefield R, Fowler VM. Defining actin filament length in striated muscle: rulers and caps or dynamic stability? Annu Rev Cell Dev Biol. 1998;14:487-525.

 

1997

Kuhlman PA, Fowler VM. Purification and characterization of an alpha 1 beta 2 isoform of CapZ from human erythrocytes: cytosolic location and inability to bind to Mg2+ ghosts suggest that erythrocyte actin filaments are capped by adducin. Biochemistry. 1997 Nov 4;36(44):13461-72.

Fowler VM. Capping actin filament growth: tropomodulin in muscle and nonmuscle cells. Soc Gen Physiol Ser. 1997;52:79-89.

Porter GA, Scher MG, Resneck WG, Porter NC, Fowler VM, Bloch RJ. Two populations of beta-spectrin in rat skeletal muscle. Cell Motil Cytoskeleton. 1997;37(1):7-19. 41.

 

1996

Kuhlman PA, Hughes CA, Bennett V, Fowler VM. A new function for adducin: calcium/calmodulin-regulated capping of the barbed ends of actin filaments. J Biol Chem. 1996 Apr 5;271(14):7986-91.

Fowler VM, Vale R. Cytoskeleton. Curr Opin Cell Biol. 1996 Feb;8(1):1-3.

Fowler VM. Regulation of actin filament length in erythrocytes and striated muscle. Curr Opin Cell Biol. 1996 Feb;8(1):86-96.

 

1995

Gregorio CC, Weber A, Bondad M, Pennise CR, Fowler VM. Requirement of pointed-end capping by tropomodulin to maintain actin filament length in embryonic chick cardiac myocytes. Nature. 1995 Sep 7;377(6544):83-6.

Gregorio CC, Fowler VM. Mechanisms of thin filament assembly in embryonic chick cardiac myocytes: tropomodulin requires tropomyosin for assembly. J Cell Biol. 1995 May;129(3):683-95.

White RA, Dowler LL, Woo M, Adkison LR, Pal S, Gershon D, Fowler VM. The tropomodulin (Tmod) gene maps to chromosome 4, closely linked to Mup1. Mamm Genome. 1995 May;6(5):332-3.

 

1994

Weber A, Pennise CR, Babcock GG, Fowler VM. Tropomodulin caps the pointed ends of actin filaments. J Cell Biol. 1994 Dec;127(6 Pt 1):1627-35.

Babcock GG, Fowler VM. Isoform-specific interaction of tropomodulin with skeletal muscle and erythrocyte tropomyosins. J Biol Chem. 1994 Nov 4;269(44):27510-8.

Fowler VM. Thyroid-associated ophthalmopathy. Clin Immunol Immunopathol. 1994 Oct;73(1):152.

Ursitti JA, Fowler VM. Immunolocalization of tropomodulin, tropomyosin and actin in spread human erythrocyte skeletons. J Cell Sci. 1994 Jun;107 (Pt 6):1633-9.

Woo MK, Fowler VM. Identification and characterization of tropomodulin and tropomyosin in the adult rat lens. J Cell Sci. 1994 May;107 ( Pt 5):1359-67.

Gregorio CC, Repasky EA, Fowler VM, Black JD. Dynamic properties of ankyrin in T lymphocytes: colocalization with spectrin and protein kinase C beta. J Cell Biol. 1994 Apr;125(2):345-58.

 

1993

Fowler VM, Sussmann MA, Miller PG, Flucher BE, Daniels MP. Tropomodulin is associated with the free (pointed) ends of the thin filaments in rat skeletal muscle. J Cell Biol. 1993 Jan;120(2):411-20.

 

1992

Fowler VM, Adam EJ. Spectrin redistributes to the cytosol and is phosphorylated during mitosis in cultured cells. J Cell Biol. 1992 Dec;119(6):1559-72.

Sussman MA, Fowler VM. Tropomodulin binding to tropomyosins: isoform-specific differences in affinity and stoichiometry. Eur J Biochem. 1992 Apr 1;205(1):355-62.

Sung LA, Fowler VM, Lambert K, Sussman MA, Karr D, Chien S. Molecular cloning and characterization of human fetal liver tropomodulin. A tropomyosin-binding protein. J Biol Chem. 1992 Feb 5;267(4):2616-21.

 

1990

Fowler VM. Tropomodulin: a cytoskeletal protein that binds to the end of erythrocyte tropomyosin and inhibits tropomyosin binding to actin. J Cell Biol. 1990 Aug;111(2):471-81.

Sussman MA, Battenberg E, Bloom FE, Fowler VM. Identification of two nerve growth factor-induced polypeptides in PC12 cells. J Mol Neurosci. 1990;2(3):163-74.

 

1987

Fowler VM. Identification and purification of a novel Mr 43,000 tropomyosin-binding protein from human erythrocyte membranes. J Biol Chem. 1987 Sep 15;262(26):12792-800.

 

1986

Fowler VM. Cytoskeleton: new views of the red cell network. Nature. 1986 Aug 28-Sep 3;322(6082):777-8.

Fowler VM. An actomyosin contractile mechanism for erythrocyte shape transformations. J Cell Biochem. 1986;31(1):1-9.

 

1985

Fowler VM, Davis JQ, Bennett V. Human erythrocyte myosin: identification and purification. J Cell Biol. 1985 Jan;100(1):47-55.

 

1984

Fowler VM, Bennett V. Erythrocyte membrane tropomyosin: purification and properties. J Biol Chem. 1984 May 10;259(9):5978-89.

Fowler VM, Bennett V. Tropomyosin: a new component of the erythrocyte membrane skeleton. Prog Clin Biol Res. 1984;159:57-71.

 

1982

Fowler VM, Pollard HB. Chromaffin granule membrane-F-actin interactions are calcium sensitive. Nature. 1982 Jan 28;295(5847):336-9.

Fowler VM, Pollard HB. In vitro reconstitution of chromaffin granule-cytoskeleton interactions: ionic factors influencing the association of F-actin with purified chromaffin granule membranes. J Cell Biochem. 1982;18(3):295-311.

Pollard HB, Creutz CE, Fowler V, Scott J, Pazoles CJ. Calcium-dependent regulation of chromaffin granule movement, membrane contact, and fusion during exocytosis. Cold Spring Harb Symp Quant Biol. 1982;46 Pt 2:819-34.

 

1981

Luna EJ, Fowler VM, Swanson J, Branton D, Taylor DL. A membrane cytoskeleton from Dictyostelium discoideum. I. Identification and partial characterization of an actin-binding activity. J Cell Biol. 1981 Feb;88(2):396-409.

Fowler VM, Luna EJ, Hargreaves WR, Taylor DL, Branton D. Spectrin promotes the association of F-actin with the cytoplasmic surface of the human erythrocyte membrane. J Cell Biol. 1981 Feb;88(2):388-95.

 

1980

Fowler V, Taylor DL. Spectrin plus band 4.1 cross-link actin: regulation by micromolar calcium. J Cell Biol. 1980 May;85(2):361-76.

 

1977

Fowler V, Branton D. Lateral mobility of human erythrocyte integral membrane proteins. Nature. 1977 Jul 7;268(5615):23-6.