News & Updates

May 2017: Have a look at this month's Biophysical Society's newsletter , which discusses Velia and Roberto Dominguez's new comprehensive review on
Tropomodulins and Leiomodins

May 2017: Velia and Cathy will be at the Annual ARVO meeting . Cathy will be presenting "F-actin stabilizing proteins, tropomodulin 1 and γ-tropomyosin, play diverse roles in maintaining lens cell morphology, biomechanical integrity and transparency" on Tuesday. On Wednesday, Velia will be giving a talk entitled, "Actin–rich membrane domains non-coordinately regulate lens fiber cell morphogenesis, transparency and mechanics".

March 2017: Congratulations to Cathy! Her eye lens fiber image was chosen as the featured photo on ISER's Eyes on the World Newsletter!

January 2017: Check out Dave's recent publication in the Journal of Microscopy on how to measure thin filament lengths using DDecon. DDecon can be downloaded here !

Welcome to the laboratory of Prof. Velia M. Fowler: the Laboratory for Cellular Architecture!


We’re located in the Department of Cell and Molecular Biology at The Scripps Research Institute, situated on the beautiful Torrey Pines mesa in La Jolla, CA (see map).  The Fowler laboratory studies cellular architecture: how cells spatially organize themselves and their interior compartments to achieve intricate geometries, mechanical strength, and physiological function.  The principal driver of cellular architecture is the cytoskeleton, a collection of specialized and dynamic “building blocks” and “struts” that act as a cell’s structural scaffolding.  Our investigations into the cytoskeleton focus on structural elements known as actin filaments, with a particular emphasis on the functions of the tropomodulin and tropomyosin families of proteins that interact with and regulate actin filaments.  Feel free to use this website as a resource to learn about the exciting science in our laboratory.