News & Updates

September 2017: Alyson will be presenting her work on the regulation of red blood cell shape at this year's TSRI Graduate Student Symposium in Lake Arrowhead. Good luck Alyson!

August 2017: Our summer interns, Alyssa and Dorothy, will be showcasing their hard work that they put in this summer. Check out their poster entitled "Effects of Non-Muscle Myosin IIA Mutations on Eye Lens Structure and Function" at the Hazen Courtyard. Great job!

August 2017: Kasturi was selected for a Judith Graham Pool Post-doctoral Fellowship from the National Hemophilia Foundation! Congratulations Kasturi!

July 2017: Roberta's paper "Tropomodulin1 Controls Erythroblast Enucleation via Regulation of F-Actin in the Enucleosome" was just published in Blood. Congrats Roberta!

July 2017: Check out our new paper "Stabilization of F-actin by tropomyosin isoforms regulates the morphology and mechanical behavior of red blood cells" in MBoC.

July 2017: Roberta and Alyson are presenting their work at this year's Red Blood Cells - Gordon Research Conference. Have a great time in Newport, RI!

Welcome to the laboratory of Prof. Velia M. Fowler: the Laboratory for Cellular Architecture!

 

We’re located in the Department of Molecular Medicine at The Scripps Research Institute, situated on the beautiful Torrey Pines mesa in La Jolla, CA (see map).  The Fowler laboratory studies cellular architecture: how cells spatially organize themselves and their interior compartments to achieve intricate geometries, mechanical strength, and physiological function.  The principal driver of cellular architecture is the cytoskeleton, a collection of specialized and dynamic “building blocks” and “struts” that act as a cell’s structural scaffolding.  Our investigations into the cytoskeleton focus on structural elements known as actin filaments, with a particular emphasis on the functions of the tropomodulin and tropomyosin families of proteins that interact with and regulate actin filaments.  Feel free to use this website as a resource to learn about the exciting science in our laboratory.

 

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