In Reverse Chronological Order.
 
  • Hein, J.E., Krasnova, L.B., Iwasaki, M., Fokin V.V. Cu-Catalyzed Azide-Alkyne Cycloaddition: Preparation of tris((1-Benzyl-1H-1,2,3-triazolyl)mehtyl)amine. Org. Synth. 2011, 88, 238-246. PDF
  • Krasnova, L.B., Hein, J.E., Fokin, V.V. Synthesis of 7-Aza-5-deazapurine Analogues via Copper(I)-catalyzed Hydroamination of Alkynes and 1-Iodoalkynes. J. Org. Chem. 2010, 75, 8662-8665. doi:10.1021/jo1016376
  • Jiaranaikulwanitch, J., Boonyarat, C., Fokin, V. V., Vajragupta, O. Triazolyl tryptoline derivatives as β-secretase inhibitors. Bioorg. Med. Chem. Lett. 2010, 20, 6572-6576. doi:10.1016/j.bmcl.2010.09.043
  • Kwok, S. W., Fotsing, J. R., Fraser, R. J., Rodionov, V. O., Fokin, V. V. Transition-metal-free catalytic synthesis of 1,5-diaryl-1,2,3-triazoles. Org. Lett. 2010, 12, 4217-4219. doi:10.1021/ol101568d
  • Radic, Z., Kalisiak, J., Fokin, V. V., Sharpless, K. B., Taylor, P. Interaction kinetics of oximes with native, phosphylated and aged human acetylcholinesterase. Chem. Biol. Interact. 2010, 187, 163-166. doi:10.10216/j.cbi.2010.04.014
  • Raushel, J., Fokin, V. V. Efficient synthesis of 1-sulfonyl-1,2,3-triazoles. Org. Lett., 2010, 12, 4952-4955. doi:10.1021/ol102087r
  • Hein, J. E., Fokin, V. V. “Copper-Catalyzed Dipolar Cycloaddition and Beyond: New Reactivity of Copper(I) Acetylides. Chem. Soc. Rev. 2010, 39, 1302-1315. doi:10.1039/b904091a
  • Grimster, N. P; Zhang, L.; Fokin, V. V. Synthesis and Reactivity of Rhodium(II) Azavinyl Carbenes. J. Am. Chem. Soc., 2010,  132, 2510-2511. doi:10.1021/ja910187s
  • Chuprakov, S.; Kwok, S. W.; Zhang, L.; Lercher, L.; Fokin, V. V. Rhodium-Catalyzed Enantioselective Cyclopropanation of Olefins with N-Sulfonyl 1,2,3-Triazoles. J. Am. Chem. Soc. 2009, 131, 18034-18035. doi:10.1021/ja908075u
  • Valdez, C.A., Tripp, J.C., Miyamoto, Y., Kalisiak, J., Hruz, P., Andersen, Y.S., Brown, S.E., Kangas, K., Arzu, L.V., Davids, B.J., Gillin, F.D., Upcroft, J.A., Upcroft, P., Fokin, V.V., Smith, D.K., Sharpless, K.B., Eckmann, L.Synthesis and Electrochemistry of 2-Ethenyl and 2-Ethanyl Derivatives of 5-Nitroimidazole and Antimicrobial Activity against Giardia Lamblia. J. Med. Chem. 2009, 52, 4038-4053.
  • Hein, J.E.; Tripp, J.; Krasnova, L.; Sharpless, K.B.; Fokin, V.V. Copper(I)-Catalyzed Cycloaddition of Organic Azides and 1-Iodoalkynes. Angew Chem. 2009, 48 (43), 8018-8021.
  • Cravotto, G.; Fokin, V. V.; Garella, D.; Binello, A.; Boffa, L.; Barge, A. Ultrasound-Promoted Copper-Catalyzed Azide-Alkyne Cycloaddition. J. Comb. Chem. 2009, 12, 13-15.
  • Chanda, A.; Fokin V. V. Organic Synthesis "On Water" Chem Rev 2009, 109, 725-748.
  • Minond, D.; Saldanha, S. A.; Subramaniam, P.; Spaargaren, M.; Spicer, T.; Fotsing, J. R.; Weide, T.; Fokin, V. V.; Sharpless, K. B.; Galleni, M.; Bebrone, C.; Lassaux, P.; Hodder, P.  Inhibitors of VIM-2 by screening pharmacologically active and click-chemistry compound libraries.    Bioorganic & Medicinal Chemistry 2009, 17, 5027-5037.
  • Kalisiak, J.; Trauger, S. A.; Kalisiak, E.; Morita, H.; Fokin, V. V.; Adams, M. W. W.; Sharpless, K. B.; Siuzdak, G. Identification of a New Endogenous Metabolite and the Characterization of Its Protein Interactions through an Immobilization Approach J. Am. Chem. Soc. 2009, 131, 378-386.
  • Agnew, H.D., Rohde, R.D., Millward, S.W., Nag, A., Yeo, W.-S., Hein, J.E., Pitram, S.M., Tariq, A.A., Burns, V.M., Krom, R.J., Fokin, V.V., Sharpless, K.B., Heath, J.R.Iterative in Situ Click Chemistry Creates Antibody-Like Protein-Capture Agents. Angew. Chem., Int. Ed. 2009, 48, 4944-4948.
  • Kalisiak, J.; Sharpless, K. B.; Fokin, V. V. Efficient Synthesis of 2-Substituted-1,2,3-Triazoles Org. Lett. 2008, 10, in press.
  • Boren, B. C.; Narayan, S.; Rasmussen, L. K.; Zhang, L.; Zhao, H.; Lin, Z.; Jia, G.; Fokin, V. V. Ruthenium-Catalyzed Azide-Alkyne Cycloaddition: Scope and Mechanism J. Am. Chem. Soc. 2008, 130, 8923-8930.
  • Raushel, J.; Pitram, S. M.; Fokin, V. V. Efficient Synthesis of Sulfonyl Azides from Sulfonamides Org. Lett. 2008, 10, 3385-3388.
  • Yoo, E. J.; Ahlquist, M.; Bae, I.; Sharpless, K. B.; Fokin, V. V.; Chang, S. Mechanistic Studies on the Cu-Catalyzed Three-Component Reactions of Sulfonyl Azides, 1-Alkynes and Amines, Alcohols, or Water: Dichotomy Via a Common Pathway J. Org. Chem. 2008, 73, 5520-5528.
  • Grecian, S.; Fokin, V. V. Ruthenium-Catalyzed Cycloaddition of Nitrile Oxides and Alkynes: Practical Synthesis of Isoxazoles Angew. Chem. Int. Ed. 2008, 47, 8285-8287.
  • Horneff, T.; Chuprakov, S.; Chernyak, N.; Gevorgyan, V.; Fokin, V. V. Rhodium-Catalyzed Transannulation of 1,2,3-Triazoles with Nitriles J. Am. Chem. Soc. 2008, 130, 14972-14974.
  • Yoo, E. J.; Ahlquist, M.; Kim, S. H.; Bae, I.; Fokin, V. V.; Sharpless, K. B.; Chang, S. Copper-Catalyzed Synthesis of N-Sulfonyl-1,2,3-Triazoles: Controlling Selectivity Angew. Chem. Int. Ed. 2007, 46, 1730-1733.
  • Wu, P.; Fokin, V. V. Catalytic Azide-Alkyne Cycloaddition: Reactivity and Applications Aldrichimica Acta 2007, 40, 7-17.
  • Rasmussen, L. K.; Boren, B. C.; Fokin, V. V. Ruthenium-Catalyzed Cycloaddition of Aryl Azides and Alkynes Org. Lett. 2007, 9, 5337-5339.
  • Fokin, V. V. Click Imaging of Biochemical Processes in Living Systems ACS Chemical Biology 2007, 2, 775-778.
  • Chan, T. R.; Fokin, V. V. Polymer-Supported Copper(I) Catalysts for the Experimentally Simplified Azide - Alkyne Cycloaddition QSAR & Combinatorial Science 2007, 26, 1274-1279.
  • Finn, M. G.; Kolb, H. C.; Fokin, V. V.; Sharpless, K. B. Concept and Applications of Click Chemistry. From the Standpoint of Advocates Kagaku to Kogyo (Tokyo, Japan) 2007, 60, 976-980.
  • Rodionov, V. O.; Presolski, S. I.; Diaz, D. D.; Fokin, V. V.; Finn, M. G. Ligand-Accelerated Cu-Catalyzed Azide-Alkyne Cycloaddition: A Mechanistic Report J. Am. Chem. Soc. 2007, 129, 12705-12712.
  • Liu, Y.; Diaz, D. D.; Accurso, A. A.; Sharpless, K. B.; Fokin, V. V.; Finn, M. G. Click Chemistry in Materials Synthesis. III. Metal-Adhesive Polymers from Cu(I)-Catalyzed Azide-Alkyne Cycloaddition J. Polym. Sci., Part A: Polym. Chem. 2007, 45, 5182-5189.
  • Ahlquist, M.; Fokin, V. V. Enhanced Reactivity of Dinuclear Copper(I) Acetylides in Dipolar Cycloadditions Organometallics 2007, 26, 4389-4391.
  • Vestberg, R.; Malkoch, M.; Kade, M.; Wu, P.; Fokin, V. V.; Sharpless, K. B.; Drockenmuller, E.; Hawker, C. J. Role of Architecture and Molecular Weight in the Formation of Tailor-Made Ultrathin Multilayers Using Dendritic Macromolecules and Click Chemistry J. Polym. Sci., Part A: Polym. Chem. 2007, 45, 2835-2846.
  • Hawker, C. J.; Fokin, V. V.; Finn, M. G.; Sharpless, K. B. Bringing Efficiency to Materials Synthesis: The Philosophy of Click Chemistry Aust. J. Chem. 2007, 60, 381-383.
  • Whiting, M.; Muldoon, J.; Lin, Y.-C.; Silverman, S. M.; Lindstrom, W.; Olson, A. J.; Kolb, H. C.; Finn, M. G.; Sharpless, K. B.; Elder, J. H.; Fokin, V. V. Inhibitors of HIV-1 Protease by Using in Situ Click Chemistry Angew. Chem. Int. Ed. 2006, 45, 1435-1439.
  • Whiting, M.; Tripp, J. C.; Lin, Y.-C.; Lindstrom, W.; Olson, A. J.; Elder, J. H.; Sharpless, K. B.; Fokin, V. V. Rapid Discovery and Structure-Activity Profiling of Novel Inhibitors of Human Immunodeficiency Virus Type 1 Protease Enabled by the Copper(I)-Catalyzed Synthesis of 1,2,3-Triazoles and Their Further Functionalization J. Med. Chem. 2006, 49, 7697-7710.
  • Vestberg, R.; Malkoch, M.; Kade, M.; Wu, P.; Fokin, V. V.; Sharpless, K. B.; Hawker, C. J. Layer-by-Layer Deposition of Dendrimers Using Click-Chemistry PMSE Preprints 2006, 94, 256-257.
  • Whiting, M.; Fokin, V. V. Copper-Catalyzed Reaction Cascade: Direct Conversion of Alkynes into N-Sulfonylazetidin-2-Imines Angew. Chem. Int. Ed. 2006, 45, 3157-3161.
  • Cassidy, M. P.; Raushel, J.; Fokin, V. V. Practical Synthesis of Amides from in Situ Generated Copper(I) Acetylides and Sulfonyl Azides Angew. Chem. Int. Ed. 2006, 45, 3154-3157.
  • Wu, P.; Hilgraf, R.; Fokin, V. V. Osmium-Catalyzed Olefin Dihydroxylation and Aminohydroxylation in the Second Catalytic Cycle Adv. Synth. Cat. 2006, 348, 1079-1085.
  • Zhang, L.; Chen, X.; Xue, P.; Sun, H. H. Y.; Williams, I. D.; Sharpless, K. B.; Fokin, V. V.; Jia, G. Ruthenium-Catalyzed Cycloaddition of Alkynes and Organic Azides J. Am. Chem. Soc. 2005, 127, 15998-15999.
  • Himo, F.; Lovell, T.; Hilgraf, R.; Rostovtsev Vsevolod, V.; Noodleman, L.; Sharpless, K. B.; Fokin Valery, V. Copper(I)-Catalyzed Synthesis of Azoles. DFT Study Predicts Unprecedented Reactivity and Intermediates J. Am. Chem. Soc. 2005, 127, 210-216.
  • Malkoch, M.; Schleicher, K.; Drockenmuller, E.; Hawker, C. J.; Russell, T. P.; Wu, P.; Fokin, V. V. Structurally Diverse Dendritic Libraries: A Highly Efficient Functionalization Approach Using Click Chemistry Macromolecules 2005, 38, 3663-3678.
  • Rodionov, V. O.; Fokin, V. V.; Finn, M. G. Mechanism of the Ligand-Free Cui-Catalyzed Azide-Alkyne Cycloaddition Reaction Angew. Chem. Int. Ed. 2005, 44, 2210-2215.
  • Narayan, S.; Muldoon, J.; Finn, M. G.; Fokin, V. V.; Kolb, H. C.; Sharpless, K. B. "On Water": Unique Reactivity of Organic Compounds in Aqueous Suspension Angew. Chem. Int. Ed. 2005, 44, 3275-3279.
  • Meng, J.-c.; Fokin, V. V.; Finn, M. G. Kinetic Resolution by Copper-Catalyzed Azide-Alkyne Cycloaddition Tetrahedron Lett. 2005, 46, 4543-4546.
  • Hansen, T. V.; Wu, P.; Fokin, V. V. One-Pot Copper(I)-Catalyzed Synthesis of 3,5-Disubstituted Isoxazoles J. Org. Chem. 2005, 70, 7761-7764.
  • Feldman, A. K.; Colasson, B.; Sharpless, K. B.; Fokin, V. V. The Allylic Azide Rearrangement: Achieving Selectivity J. Am. Chem. Soc. 2005, 127, 13444-13445.
  • Loren, J. C.; Krasinski, A.; Fokin, V. V.; Sharpless, K. B. NH-1,2,3-Triazoles from Azidomethyl Pivalate and Carbamates: Base-Labile N-Protecting Groups Synlett 2005, 2847-2850.
  • Wu, P.; Malkoch, M.; Hunt, J. N.; Vestberg, R.; Kaltgrad, E.; Finn, M. G.; Fokin, V. V.; Sharpless, K. B.; Hawker, C. J. Multivalent, Bifunctional Dendrimers Prepared by Click Chemistry Chem. Comm. 2005, 5775-5777.
  • Krasinski, A.; Fokin, V. V.; Sharpless, K. B. Direct Synthesis of 1,5-Disubstituted-4-Magnesio-1,2,3-Triazoles, Revisited Org. Lett. 2004, 6, 1237-1240.
  • Punna, S.; Diaz, D. D.; Li, C.; Sharpless, K. B.; Fokin, V. V.; Finn, M. G. Click Chemistry in Polymer Synthesis Polym. Prepr. (Am. Chem. Soc., Div. Polym. Chem.) 2004, 45, 778-779.
  • Lewis, W. G.; Magallon, F. G.; Fokin, V. V.; Finn, M. G. Discovery and Characterization of Catalysts for Azide-Alkyne Cycloaddition by Fluorescence Quenching J. Am. Chem. Soc. 2004, 126, 9152-9153.
  • Chan, T. R.; Hilgraf, R.; Sharpless, K. B.; Fokin, V. V. Polytriazoles as Copper(I)-Stabilizing Ligands in Catalysis Org. Lett. 2004, 6, 2853-2855.
  • Wu, P.; Feldman, A. K.; Nugent, A. K.; Hawker, C. J.; Scheel, A.; Voit, B.; Pyun, J.; Frechet, J. M. J.; Sharpless, K. B.; Fokin, V. V. Efficiency and Fidelity in a Click-Chemistry Route to Triazole Dendrimers by the Copper(I)-Catalyzed Ligation of Azides and Alkynes Angew. Chem. Int. Ed. 2004, 43, 3928-3932.
  • Diaz, D. D.; Punna, S.; Holzer, P.; McPherson, A. K.; Sharpless, K. B.; Fokin, V. V.; Finn, M. G. Click Chemistry in Materials Synthesis. 1. Adhesive Polymers from Copper-Catalyzed Azide-Alkyne Cycloaddition J. Polym. Sci., Part A: Polym. Chem. 2004, 42, 4392-4403.
  • Feldman, A. K.; Colasson, B.; Fokin, V. V. One-Pot Synthesis of 1,4-Disubstituted 1,2,3-Triazoles from in Situ Generated Azides Org. Lett. 2004, 6, 3897-3899.
  • Appukkuttan, P.; Dehaen, W.; Fokin, V. V.; Van der Eycken, E. A Microwave-Assisted Click Chemistry Synthesis of 1,4-Disubstituted 1,2,3-Triazoles Via a Copper(I)-Catalyzed Three-Component Reaction Org. Lett. 2004, 6, 4223-4225.
  • Shen, Z.; Go, E. P.; Gamez, A.; Apon, J. V.; Fokin, V.; Greig, M.; Ventura, M.; Crowell, J. E.; Blixt, O.; Paulson, J. C.; Stevens, R. C.; Finn, M. G.; Siuzdak, G. A Mass Spectrometry Plate Reader: Monitoring Enzyme Activity and Inhibition with a Desorption/Ionization on Silicon (Dios) Platform ChemBioChem 2004, 5, 921-927.
  • Brik, A.; Muldoon, J.; Lin, Y.-c.; Elder, J. H.; Goodsell, D. S.; Olson, A. J.; Fokin, V. V.; Sharpless, K. B.; Wong, C.-h. Rapid Diversity-Oriented Synthesis in Microtiter Plates for in Situ Screening of Hiv Protease Inhibitors ChemBioChem 2003, 4, 1246-1248.
  • Wang, Q.; Chan, T. R.; Hilgraf, R.; Fokin, V. V.; Sharpless, K. B.; Finn, M. G. Bioconjugation by Copper(I)-Catalyzed Azide-Alkyne [3 + 2] Cycloaddition J. Am. Chem. Soc. 2003, 125, 3192-3193.
  • Kitayama, T.; Yokoi, T.; Kawai, Y.; Hill, R. K.; Morita, M.; Okamoto, T.; Yamamoto, Y.; Fokin, V. V.; Sharpless, K. B.; Sawada, S. The Chemistry of Zerumbone. Part 5: Structural Transformation of the Dimethylamine Derivatives Tetrahedron 2003, 59, 4857-4866.
  • Lee, L. V.; Mitchell, M. L.; Huang, S.-J.; Fokin, V. V.; Sharpless, K. B.; Wong, C.-H. A Potent and Highly Selective Inhibitor of Human a-1,3-Fucosyltransferase Via Click Chemistry J. Am. Chem. Soc. 2003, 125, 9588-9589.
  • Andersson, M. A.; Epple, R.; Fokin, V. V.; Sharpless, K. B. A New Approach to Osmium-Catalyzed Asymmetric Dihydroxylation and Aminohydroxylation of Olefins Angew. Chem. Int. Ed. 2002, 41, 472-475.
  • Dupau, P.; Epple, R.; Thomas, A. A.; Fokin, V. V.; Sharpless, K. B. Osmium-Catalyzed Dihydroxylation of Olefins in Acidic Media: Old Process, New Tricks Adv. Synth. Cat. 2002, 344, 421-433.
  • Rostovtsev, V. V.; Green, L. G.; Fokin, V. V.; Sharpless, K. B. A Stepwise Huisgen Cycloaddition Process: Copper(I)-Catalyzed Regioselective "Ligation" Of Azides and Terminal Alkynes Angew. Chem. Int. Ed. 2002, 41, 2596-2599.