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Macromolecular X-Ray Crystallography Core Facility

Major Equipment

Minstrel III, an automatic plate handling and imaging system
RoboIncubators, which can store crystallization plates in a temperature and humidity controlled environment
Leica stereomicroscope and a high powered stereoscope for manual crystal photography, crystal screening, and crystal manipulation
Gryphon Crystallization Robot, which can set up nano liter drops in minutes

Gryphon

Rigaku MicroMax-007 HFM X-ray generator with a VariMax HR optics and an X-Stream 2000 crystal cryo-freezing system
Mar345dtb image plate detector for recording X-ray diffraction patterns

mar345dtb

Proteros Free Mounting System (FMS) for handling and manipulating room temperature grown crystals for diffraction optimization

FMS head

microscope

crystal

Crystal transformation by precise control of humidity change using FMS. Dramatic improvement of diffraction patterns (20 A to 2.7 A Bragg spacings) were seen during the crystal dehydration from Rh96% to Rh75%.

Dedicated computers for data collection and processing

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