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Informatics Core - Genomics & Biostatistics

The Genomics and Biostatistics focus area centers primarily around Next-Generation Sequencing (NGS) and RNA Microarrays.  Additionally, statistical data analysis on primary data and downstream functional analyses are available.

NGS and microarray data analysis services include:

  • RNA-Seq and microRNA-Seq data analysis
  • ChIP-Seq data analysis
  • Custom Bioinformatics workflows for NGS applications (RNA-Seq, ChIP-Seq, microRNA-Seq)
  • Gene expression analysis of in house and published microarray datasets (Affymetrix, Illumina, ...)
  • Quality control, alignment/mapping
  • de novo genome/transcriptome assembly (in the absence of a reference genome)
  • Integratation and application of published and popular algorithms and tools
  • Multiple genome browser support for visualization of NGS results
  • Develop and integrate data analysis and visualization tools, including leveraging of R and other programming languages
  • Establishing and maintaining customized genomic databases
  • Statistical support and consultation including providing advice on various aspects of statistical design and analysis
  • Support grant applications with experimental design recommendations and power/sample analysis

Downstream Analysis Services include:

  • Pathway and gene ontology analysis
  • Classification/Clustering analysis
  • Gene annotation
  • Data visualization
  • Promoter analysis
  • Preparation of figures for Publications

Personnel:

  • Adrian Reich, Bioinformatics Analyst
  • Gogce Crynen, Bioinformatics Analyst