|
|
 |
Florida Faculty and Professional Staff
Junli Luo
Assistant Professor
Department of Cancer Biology
TSRI - 2008
Education
Clinical Medical Science - Hunan Medical University, China
Basic Biomedical Science - German Cancer Research Center, Germany; University of California, San Diego, USA
Research Focus
The research in Luo’s lab focuses on mechanistic and translational research in molecular signaling that connects epigenetic factors with genetic events during tumor genesis, progression and metastasis. Specifically, Luo’s lab is working on how epigenetic signaling regulates cancer initial cells self-renewal and trans-differentiation.
Selected References
Wang, G. G., Song, J., Wang, Z., Dormann, H. L., Casadio, F., Li, H., Luo, J-L., Patel, D. J., and Allis, C. D. 2009. Haematopoietic malignancies initiated by dysregulation of a chromatin-binding PHD finger. Nature, May 19.
Kim, S., Takahashi, H., Lin, W-W., Descargues, P., Grivennikov, S., Kim Y., Luo, J-L., Karin M. 2009. Carcinoma Produced Factors Activate Myeloid Cells via TLR2 to Stimulate Metastasis.Nature, 457:102-6.
Matsuzawa, A., Tseng, P-H., Vallabhapurapu, S., Luo, J-L., Zhang, W., Wang, H., Vignali, D. A. A., Gallagher, E., Karin, M. (2008) Essential cytoplasmic translocation of a cytokine receptor-assembled signaling complex.Science, 321:663-8.
Luo, J-L., Tan, W., Ricono, J. M., Korchynskyi, O., Zhang, M., Gonias, S. L., Cheresh D. A., and Karin, M. (2007) Nuclear cytokine-activated IKKalpha controls prostate cancer metastasis by repressing Maspin. Nature, 446: 690-4.
|
|
|
|
