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Florida Faculty and Professional Staff
Kendall Nettles
Associate Professor
Department of Cancer Biology
TSRI - 2005
Education
B.A. 1990 Colgate University (Psychology)
Ph.D. 2003 University of Chicago (Cancer Biology)
1998-2003 Graduate Research Assistant for Geoffrey L. Greene, The Ben May Institute for Cancer Research, The University of Chicago
2003-2005 Post-Doctoral Fellow with Geoffrey L. Greene, The Ben May Institute for Cancer Research, the University of Chicago
Post-Doctoral Fellow with Andrzej Joachimiak, The Midwest Center for Structural Genomics, Argonne National Laboratories
Awards & Activities
Best Thesis, 2003. The Committee on Cancer Biology, The University of Chicago
Elaine Erhman Award for Research in Cancer Biology, 2002. Awarded yearly to a senior graduate Student at the University of Chicago
Research Focus
Selected References
Nettles KW, Bruning JB, Gil G, Nowak J, Sharma SK, Hahm JB, Kulp K, Hochberg RB, Zhou H, Katzenellenbogen JA, Katzenellenbogen BS, Kim Y, Joachmiak A, Greene GL. NFkappaB selectivity of estrogen receptor ligands revealed by comparative crystallographic analyses. Nat Chem Biol. 2008 4(4):241-7.
Nettles KW, Gil G, Nowak J, Metivier R, Sharma VB, Greene GL. CBP is a dosage dependent regulator of NFkB suppression by the estrogen receptor.Molecular Endocrinology, 2008, 22(2): 263-7
Bruning JB, Chalmers, MJ, Prasad S, Busby SA, Kamenecka TM, He Y, Nettles KW, Griffin PR. Partial Agonists Activate PPARα Using a Helix 12 Independent Mechanism. Structure, 2007 15(10):1258-7
Zhou HB, Nettles KW, Bruning JB, Kim Y, Joachimiak A, Sharma S, Carlson KE, Stossi F, Katzenellenbogen BS, Greene GL, Katzenellenbogen JA. Elemental isomerism: a boron-nitrogen surrogate for a carbon-carbon double bond increases the chemical diversity of estrogen receptor ligands. Chem Biol. 2007 Jun;14(6):659-69.
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