Burris, Thomas
research focuses on chemical biology of nuclear receptors, protein molecules that mediate hormone activity inside the cell that are potential drug targets for a number of diseases including prostate, breast and colon cancers, as well as type 2 diabetes, atherosclerosis, metabolic syndrome and autoimmunity.
Feng, Yangbo
focuses on the lead identification and optimization of drug candidates.
Kishi, Shuji
aims to develop a high-throughput processing system for gene identification and phenotype characterization particularly associated with age-related disorders in humans, using zebarfish as an amenable vertebrate model system.
Petrie, Howard
focuses on the production of specialized blood cells called T lymphocytes, which are central mediators of the immune response. Understanding this is central in developing treatments for immunodeficiencies resulting from environmental exposure (such as HIV/AIDS) or aging.
Weissmann, Charles
elucidates the structure of prions, the mechanism of their replication and the processes by which they enter cells and are released from them.