Ayad, Nagi G.
studies the cell biological basis of cell cycle exit and differentiation of neuronal precursors as it relates to cancer and nerve regeneration.
Bois, Philippe
works to determine the mechanisms that define and control recombinogenic regions in complex mammalian genomes.
Burris, Thomas
research focuses on chemical biology of nuclear receptors, protein molecules that mediate hormone activity inside the cell that are potential drug targets for a number of diseases including prostate, breast and colon cancers, as well as type 2 diabetes, atherosclerosis, metabolic syndrome and autoimmunity.
Conkright, Michael
studies the molecular events that govern the conversion of the cyclic AMP signaling cascade into transcriptional activation of target gene using cell-based high-throughput technologies.
Izard, Tina
studies the structural dynamics of signaling mediators of adhesion junctions.
Kodadek, Thomas
focuses his research in the area of chemical biology, deciphering the roles of the proteasome in transcription and understanding the mechanism of action of the hormone orexin.
Luo, Junli
focuses on mechanistic and translational research in molecular signaling that connects epigenetic factors with genetic events during tumor genesis, progression and metastasis
Miller, Courtney
is working to develop novel therapeutics for the treatment of memory disorders by targeting the epigenetic and synaptic contributors.
Paegel, Brian
studies the controlled synthesis and engineering of phospholipid vesicles and emulsions, microfluidic circuit design, and directed evolution of membrane-associated transporters, pores, and receptors.
Petrie, Howard
focuses on the production of specialized blood cells called T lymphocytes, which are central mediators of the immune response. Understanding this is central in developing treatments for immunodeficiencies resulting from environmental exposure (such as HIV/AIDS) or aging.
Tellinghuisen, Timothy
focuses on understanding the assembly, composition, and activities of the RNA replication machinery of the hepatitis c virus
Weissmann, Charles
elucidates the structure of prions, the mechanism of their replication and the processes by which they enter cells and are released from them.
