Scripps Florida

Faculty

Publications

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Research & Faculty

Department of Metabolism & Aging

Representative Publications

  1. Cowley MA, Smith RG, Diano S, Tschop M, Pronchik N, Grove KL, Strasburger CJ, Bidlingmaier M, Esterman M, Heiman ML, Garcia-Segura LM, Nillni EA, Mendez P, Low MJ, Sotonyi P, Friedman J, Liu H, Pinto S, Colmers W, Cone RD, Horvath TL (2003) Distribution and mechanism of action of ghrelin in the CNS demonstrates novel hypothalamic circuit regulating energy homeostasis. Neuron 37:550-553.
  2. Smith RG, Betancourt L, Sun Y (2005) Molecular endocrinology and physiology of the aging central nervous system. Endocrine Reviews 26:203-250.
  3. Smith RG (2005) Development of growth hormone secretagogues. Endocrine Reviews 26(3):346-360.
  4. Jiang H, Betancourt L, Smith RG (2006) Ghrelin amplifies dopamine signaling by crosstalk involving Formation of GHS-R/D1R Heterodimers. Molecular Endocrinology 20:1772-1785.
  5. Sun Y, Asnicar M, Saha PK, Chan L, Smith RG (2006) Ablation of ghrelin gene improves the diabetic but not obese phenotype of ob/ob mice. Cell Metabolism 3:379-386.
  6. Strowski MZ, Cashen DE, Birzin ET, Yang L, Singh V, Jacks TM, Nowak K, Rohrer SP, Patchett AA, Smith RG, and Schaeffer JM (2006) Antidiabetic activity of a highly potent and selective non-peptide somastostatin receptor subtype-2 agonist. Endocrinology 147:4664-4673.
  7. Wang G-L, Shi X, Salisbury E, Sun Y, Albrecht JH, Smith RG and Timchenko NA (2006) Cyclin D3 maintains growth inhibitory activity of C/EBP by stabiliziang C/EBP-cdk2 and C/EBP-Brm complexes. Molecular and Cellular Biology 26: 2570-2582.
  8. Wang G-L, Shi X, Salisbury E, Sun Y, Albrecht JH, Smith RG and Timchenko NA (2007) Growth Hormone Corrects Proliferation and Transcription of Phosphoenolpyruvate Carboxykinase in Livers of Old Mice via Elimination of CCAAT/Enhancer-binding Protein-Brm Complex (2007) J. Biol. Chem. 282 1468 - 1478
  9. Dixit VD, Yang H, Sun Y, Weeraratna AT, Youm Y-H, Smith RG and Taub DD (2007) Ghrelin promotes thymopoiesis during aging. Journal of Clinical Investigation 117:2778-2790.
  10. Kapás L, Sun Y, Smith RG, Krueger JM (2007) Spontaneous sleep and homeostatic sleep regulation in ghrelin knockout mice. Am J Physiol Regul Integr Comp Physiol. 293:R510-7.
  11. Sun Y, Butte NF, Hicks LM and Smith RG (2008) Characterization of adult ghrelin and ghrelin receptor knockout mice under positive and negative energy balance. Endocrinology 149:843-850.
  12. Garcia JM, Cata JP, Dougherty PM and Smith RG (2008) Ghrelin prevents cisplatin-induced mechanical hyperalgesia and cachexia. Endocrinology 149:455-460.